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磺胺嘧啶

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Objective: To know the sulfonamides residue level of the animality food, inquiry into the source of its pollution, evaluate the safety of its meal, a high performance liquid chromatography method was developed for determination the sulfonamides residues of sulfadiazine, sulfamonomethoxinne, sulfamonomethoxine and sulfaquinxalin in pork.

目的:为了解动物性食品中兽药残留水平,探讨其污染来源,评价其膳食安全性,因此建立猪肌肉组织中磺胺嘧啶、磺胺甲恶唑、磺胺对甲氧嘧啶、磺胺喹恶啉残留量的高效液相色谱测定方法。

The products include two series: Sulfa drugs Industrial Sulfanilamide, Crystel Sulfanilamide, Sulfaguanidine, Sulfadimidine(Sodium, Sulfadiazine, Sulfathiazole Sodium, Sulfaquinoxaline Sodium, Sulfameter Dimethyl Sulfate, Nitromethane, Hydroxylamine Hcl.

本公司专业生产化工、医药中间体,产品主要包括磺胺(工业磺胺、结晶磺胺、磺胺脒、磺胺二甲嘧啶、磺胺嘧啶、磺胺噻唑钠、磺胺喹噁啉钠、磺胺五甲氧嘧啶)及硫酸二甲酯(硫酸二甲酯、硝基甲烷、烟酸羟胺)两大系列。

Object: A specific and sensitive liquid chromatography tandem mass spectrometry method was developed for the multiresidue determination of sulfisomidine, sulfapyridine, sulfamerazine, sulfamethoxazole, sulfisoxazole, sulfadiazine, sulfamethizole, sulfachlorpyridazine, sulfamethoxypyridazine, sulfadimethoxine, sulfamonomethoxine, sulfathiazole, sulfadoxine, sulfaquinoxaline, sulfanilamide, sulfaguanidine, sulfamoxole, sulfameter, sulfadimidine, sulfacetamide, sulfaphenazole, sulfanitran, sulfabenzamide and a potentiator, trimethoprim, in meat.

目的:建立猪肉中磺胺及其增效剂多残留检测的液相色谱-串联质谱法,包括磺胺二甲异嘧啶、磺胺吡啶、磺胺甲基嘧啶、磺胺甲基异噁唑、磺胺二甲异噁唑、磺胺嘧啶、磺胺甲噻二唑、磺胺氯哒嗪、磺胺甲氧哒嗪、磺胺间二甲氧嘧啶、磺胺-6-甲氧嘧啶、磺胺噻唑、磺胺邻二甲氧嘧啶、磺胺喹噁啉、磺胺、磺胺脒、磺胺噁唑、磺胺甲氧嘧啶、磺胺二甲嘧啶、磺胺醋酰、磺胺苯吡唑、磺胺硝苯、磺胺苯酰和甲氧苄氨嘧啶。

E. sulfadiazine, sulfamerazine and sulfadimidine (SM2), by capillary zone electrophoresis with conductivity detection was developed.

采用毛细管电泳-电导法建立了磺胺嘧啶、磺胺甲嘧啶、磺胺二甲嘧啶3种结构相近磺胺药物的分离检测方法。

The analysis method on six sulfonamides in milk, namely sulfamerazine, sulfamethazine, sulfamethoxazole, sulfamonomethoxine, sulfadimethoxine and sulfadiazine was studied.

研究了牛奶中磺胺嘧啶、磺胺甲基嘧啶、磺胺二甲基嘧啶、磺胺甲噁唑、磺胺间甲氧嘧啶、磺胺二甲氧嘧啶六种磺胺类抗生素的多残留高效液相色谱分析方法。

Samples of animal manure were collected in Jiangsu Province in 2005 to 2006, the residues of sulfagidine, sulfanilamide, sulfadiazine, sulfamerazine(SM1), sulfadimidin(SM2), sulfamonomethoxine, sulfachloropyridazine, sulfamethoxazole were determined by HPLC with fluorimetric detector after pre-column derivatization.

2005—2006年采集了江苏省各市不同种类的集约化畜禽养殖场共178个畜禽粪便样品,用柱前衍生法高效液相色谱荧光检测器,检测了样品中8种磺胺类药物(磺胺胍、磺胺、磺胺嘧啶、磺胺甲嘧啶、磺胺二甲嘧啶、磺胺间甲氧嘧啶、磺胺氯哒嗪、磺胺甲恶唑)残留情况。

A method for the determination of 12 sulfonamides (sulfanilamide, sulfamonomethoxine, sulfacetamide, sulfamethoxazole, sulfadiazine, sulfisoxazole, sulfathiazole, sulfadimethoxine, sulfamerazine, sulfaquinoxaline, sulfamethazine, sulfanitran) in cosmetics was developed by ultra performance liquid chromatography with photodiode array detector. The chromatographic column used was Acquity UPLCTM BEHC C18 (50 mm×2.1 mm, 1.7 μm) and the mobile phase was acetonitrile-0.1% formic acid aqueous solution.

建立了采用超高效液相色谱-二极管阵列检测器测定化妆品中12种常见的磺胺抗生素(磺胺,磺胺间甲氧嘧啶,磺胺醋酰,磺胺甲基异唑,磺胺嘧啶,磺胺二甲异唑,磺胺噻唑,磺胺二甲氧嘧啶,磺胺甲基嘧啶,磺胺喹啉,磺胺二甲嘧啶,磺胺硝苯)的方法。

Toxic effects of twelve pesticides(abamectin, endosulfan, diflubenzuron, danitol, tricyclazole, fluroxypyr, imazalil, tebuconazole, sulfapyridine, sulfamethoxazole, sulfamethazine and sulfadiazine)at low concentration(0.01mg·L-1) on the development of sea urchinembryos were investigated in this work, and the correlation between n-octanol/water partition coefficientand relative lethality rate was investigated.

为了研究低浓度下农药对海胆胚胎的毒性影响,以及正辛醇/水分配系数与致死率的关系,实验研究了12种常见农药(阿维菌素、硫丹、除虫脲、甲氰菊酯、三环唑、使它隆、抑霉唑、戊唑醇、磺胺吡啶、磺胺甲噁唑、磺胺二甲嘧啶和磺胺嘧啶)在低浓度(0.01mg.L-1)下对光棘球海胆胚胎发育的急性毒性影响。

A UPLC method was established for the ten sulfonamides including sulfadiazine,sulfathiazole,sulfadimidine(SM2),sulfamethoxypyridazine,sulfachlorpyridazine,sulfamonomethoxine, sulfamethoxazole, sulfachloropyrazine (Esb3),sulfadimethoxine and sulfaquinoxaline in pig muscle and milk.

建立了猪肉和牛奶中磺胺嘧啶、磺胺噻唑、磺胺二甲嘧啶(SM2)、磺胺甲氧嗪、磺胺氯哒嗪、磺胺间甲氧嘧啶、磺胺甲基异噁唑、磺胺氯吡嗪(Esb3)、磺胺地索辛和磺胺喹噁啉共10种磺胺类药物残留检测的超高效液相色谱法。

Among the common sulpha drugs are sulphamerazine, sulphadiazine, and succinylsulfathiazole.

常见的磺胺药物有磺胺甲嘧啶,磺胺嘧啶和琥磺噻唑。

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