磺胺

Objective: To develop a GC method for determination of acetone in sulfadimidine.

目的：建立磺胺二甲嘧啶合成中所用有机溶剂丙酮残留量的测定方法。

The PCP model rats were randomly divided into sulfanilamide treatment group and positive control group,the normal rats were randomly divided into normal control group and negative control group.

2实验分组：正常对照组，阴性对照组，阳性对照组(建立Pc模型未给磺胺药的大鼠)和实验组(建立Pc模型并用磺胺药治疗的大鼠)。

Results showed that sulfapyridine, tricyclazole, sulfadiazine and imazalil at low concentration（0.01mg·L-1） have the highest relative lethality rate to swelling of insemination membrane, two cells, swimming blastula and prism stage, respectively, which were 3.70%, 6.19%, 5.84% and 6.07%, respectively.

实验浓度下，磺胺吡啶、三环唑、磺胺嘧啶和抑霉唑分别对受精膜举起期、2细胞期、上浮囊胚期和棱柱幼体期相对致死率最高，分别达到3.70%、6.19%、5.84%和6.07%。

The proposed method has been applied to the determination of SD and SM2 in commercial compound sulfonamide tablets and powders with satisfactory results.

应用于市售复方磺胺嘧啶片和小儿安散中磺胺药物的含量测定，取得满意结果。

objective: to explore the curative effects of the sulfadiazinmu argenteum combined with acyclovir on treatment herpes zoster.methods:118 cases patient randomly were divided into treatment group and control group.in treatment group the sulfadiazinmu argenteum be spread the surface of herpes and acyclovir be intravenous dripped;in control group the compound calamine lotion be external used and acyclovir be intravenous dripped.

目的：探讨应用磺胺嘧啶银和阿昔洛韦治疗带状疱疹的疗效。方法：118例病人随机分为实验组和对照组，实验组应用磺胺嘧啶银外涂创面，静滴阿昔洛韦进行治疗；对照组外用复方炉甘石洗剂、静滴阿昔洛韦治疗。

As a kind of artificial molecular recognition materials ,the applications of imprinted polymers including in Chromatogram analysis and separate,SolidPhaseExtraction, emulational transducer and so on which were summarized in detail . Analytic technique of iatric ort was introduced briefly.

对药物残留分析技术也作了扼要的介绍，指出了利用分子印迹技术合成磺胺类药印迹聚合物来分离和测定磺胺类药物，对食品工业和制药工业的质量控制有十分重要的意义。

It was found that photochemical deposition of Hg occurred at the layer of TiO2 covering the surface of titanium electrode under UV irradiation, the adsorption of sulfadiazine on the photochemically deposited Hg was stronger than that on the electrochemically deposited Hg, and a method for the determination of sulfadiazine was proposed by the adsorptive stripping voltammetry based on photo-chemical deposition of Hg on Ti electrode.

该研究发现采用紫外光照射钛电极表面氧化钛层能够光催化还原Hg(上标致2+)生成Hg微粒，在Ti基电极上光化学沉积Hg比电化学沉积Hg对磺胺嘧啶具有更强的吸附作用，基于光化学沉积Hg/Ti电极建立了一种吸附溶出伏安法测定磺胺嘧啶的方法。

Pharmacology function】Huang An the AN oxygen Mi Ding be in the Huang An medicine to suppress the germ a very strong kind of the function to synthesize anti-virus medicine, because of it with for germ to synthesize folic acid demand of to ammonia Ji the benzene be sour to have likeness on the structure, exchange with PABA to contend for two hydrogen folic acids to synthesize Mao, bar the germ synthesize two hydrogen folic acids to synthesize Mao, bar the germ synthesize two hydrogen folic acids, end influence nucleic acid protein of synthesize, repress thus germ of growth breed, to variety E-and E+very strongly repress a function.

磺胺间甲氧嘧啶是磺胺类药物中抑菌作用极强的一种合成抗菌药物，因其与细菌合成叶酸时所需要的对氨基苯酸在结构上具有相似性，与PABA兑争二氢叶酸合成酶，阻碍细菌合成二氢叶酸合成酶，阻碍细菌合成二氢叶酸，最终影响核酸蛋白质的合成，从而抑制细菌的生长繁殖，对多种E-及E+有很强的抑制作用。

Methods thirty cases inflicted with 3%～50% tbsa deep partial thickness burn wound, after fresh wound was debrided, the treating area was handled with heparin and sulfadiazine silver cream, while the control area was treated with sulfadiazine silver cream, until the wound healing.

伤后24h入院的烧伤患者30例， 3%～50%烧伤面积，以深ⅱ度为主，清创后实验区先用肝素钠湿敷，再用磺胺嘧啶银乳膏包扎，对照区应用磺胺嘧啶银乳膏包扎，每日1次，3天后改为半暴露。

Other major figures: Gerhard Domagk (who found that the red dye Prontosil cured strep infections, which led to the development of the sulfa drugs); Alexander Fleming (who stumbled onto the inhibition of Staph bacteria by a mold, Penicillium); Howard Florey and Ernst Chain (who purified penicillin for clinical use); Rene Dubos (who found an antibiotic in an organism in the soil); and Selman Waksman (who searched systematically among soil organisms for antibiotics and there discovered the second clinically important antibiotic, streptomycin).

其他的重要人物：Gerhard Domagk（发现红色染料偶氮磺胺可以治愈链球菌属感染，发展成为磺胺类药物）；Alexander Fleming（偶然发现霉菌，青霉菌，可以抑制葡萄球菌属细菌）；Howard Florey 和 Ernst Chain（纯化了青霉素将其应用到临床）；Rene Dubos（在土壤里一种生物体力发现了一种抗生素）；还有Selman Waksman（系统研究土壤有机体和抗生素，发现了临床第二重要的抗生素，链霉素

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。