磷酸化酶

The effects of FPL andits three ingredients on growth of ovary,on micro-and ultra-structure andAlkaline phosphatase activity of endometrium,on structure andkeratinization rate of exfoliated cells in vaginal epithelium in mice,onmicrocirculation in rat and on uterine kinesis in rabbit were respectivelyobserved by the techniques of light and electron microscopes,histochemistry,microcirculation and organ cinetography.The results have confirmed themechanism of FPL for the sterility caused by ovary standstill and persistentcorpus luteum to be as follows:(1) a weak estrogen-like role which canprompt development of ovary,proliferation and secretion of endometrium andvaginal epithelium and cornification of exfoliated cells in vaginal epithelium;(2)enhancing AKP's activity of endometrium;(3)improving microcirculation;(4) exciting uterus.

分别采用光学显微镜和电子显微镜技术、组织化学技术、微循环技术和器官运动描记等现代医学实验技术，观察了促孕液对小白鼠的卵巢发育、子宫内膜的显微和超微结构和碱性磷酸酶活性、阴道上皮结构和脱落细胞的角化率、对大白鼠的微循环和对家兔的子宫运动的影响，结果证实了促孕液治疗卵巢静止、持久黄体的机理：(1)微弱的雌激素样作用，能刺激卵泡发育，促进子宫内膜和阴道上皮增生、分泌和阴道上皮脱落细胞角化；(2)提高子宫内膜碱性磷酸酶的活性；(3)改善微循环；(4)促进子宫运动。

Results showed that enzyme activities were significantly different, urease activity: park＞school＞residence＞industry＞road; phosphatase activity: park＞industry＞school＞residence＞road; invertase activity: residence＞park＞industry＞road＞school; But the dynamic patterns of SOC mineralization from different functional areas were similarly, the rate of SOC mineralization decreased quickly at the beginning, and then decreased slowly during the middle incubation time, and keep relatively constant during the later incubation time, and fitted to logarithmic equation with incubation time.

结果表明：不同功能区土壤酶活性差异显著，脲酶：公园＞学校＞居民区＞工厂＞道路；磷酸酶：公园＞工厂＞校园＞居民区＞道路；转化酶：居民区＞公园＞工厂＞道路＞学校；但不同功能区土壤有机碳矿化过程动态表现出相同规律，在培养前期有机碳矿化速率迅速下降，培养中期缓慢下降，培养后期保持相对稳定的趋势，有机碳矿化与培养时间符合对数关系；整个培养期内，土壤有机碳矿化速率及累计矿化量公园＞工厂＞道路＞学校＞居民区。

In addition, SW480 and HCT116 cells were treated with deoxycholic acid for 15, 30, 45, 60, 90 and 120 minutes. It was found that the deoxycholic acid treated cells showed an elevation of ATP activity by 12.35 %, 20.08 %, 29.69 %, 33.56 %, 45.85 %, 54.32 %, respectively. While the HCT116 treated cells, showed an elevation of ATP activity by 3.69 %, 5.59 %, 8.52 %, 12.26 %, 16.52 %, 19.71%, respectively.From the experiments conducted using the cell lines described above, it was further confirmed that genes CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1), AKR1D1 (aldo-keto reductase family 1, member D1), ALDH1A1 (aldehyde dehydrogenase 1 family, member A1), BAAT (bile acid Coenzyme A: amino acid N-acyltransferase), ABCA1 (ATP-binding cassette, sub-family A, member 1), APOC3 (apolipoprotein C-III), LIPA, LIPE (lipase, hormone-sensitive), PTGER2 (prostaglandin E receptor 2) and PTGS2 (prostaglandin-endoperoxide synthase 2) were up-regulated.

此外，为了证实其脂肪代谢产物胆酸对细胞癌化的影响，亦使用SW480和HCT116细胞株，经由脱氧胆酸在15分钟、30分钟、45分钟、60分钟、90分钟和120分钟处理后，其细胞增生比率分别有12.35%，20.08%，29.69%，33.56%，45.85%和54.32%(p.05)以及3.69%，5.59%，8.52%，12.26%，16.52%和19.71%(p.05)上升情形，并从这些细胞株进一步证实CYP7A1(细胞色素P450-7A1)、AKR1D1(醇醛酮还原酶-1-D1)、ALDH1A1(醛脱氢酶-1-A1)、BAAT(胆酸辅酶A：氨基酸N-醯基转移酶)、ABCA1(三磷酸腺苷结合盒转运体A1)、APOC3、LIPA、LIPE(脂肪酶/激素敏感脂肪酶)、PTGER2(前列腺素E受体2)和PTGS2(前列腺素内过氧化物合成酶2)等基因表现皆有呈现向上调控的情形。

By TUNEL and ultrastructural observation,the results showed that cadmium toxication caused apoptosis in testes,and adding selenium may decrease the effect. 5.Cadmium can affect the activites of several enzymes in biomembrane, Such as SDH,ALP,Mg2+-ATPase,G-6-P,Ca2+-ATPase and lead to metabolical disorder in tissues.

通过酶组化检测，证明镉能影响公鸡睾丸组织中酶活性，即琥珀酸脱氢酶、碱性磷酸酶、Mg~(2+)激活的三磷酸腺苷酶Mg~(2+-ATPase、葡萄糖-6磷酸酶(G-6-Pase)、Ca~(2-)激活的三磷酸腺苷酶Ca~(2--ATPase活性下降，酸性磷酸酶活性升高，导致睾丸组织损伤。

In this research, the complete ipt gene was cloned from Agrobacterium pTiAch 58 Hind Ⅲ fragment and its promoter was re-constructed so that following three chimaeric genes were created:(1) ipt promoter plus ipt coding region and terminator ,(2) RuBP SSU 301 promoter from petunia plus ipt coding region and terminator ,(3) pea seed-specific vicilin promoter plus ipt coding region and terminator .

将ipt基因克隆后对其启动子进行了改造，分别构建了如下三种基因：（1）ipt启动子+ipt编码区和3′区，（2）磷酸核酮糖羧化酶小亚基启动子SSU 301+ipt编码区和3′区，（3）豌豆种子特异性启动子vicilin+ipt编码区和3′区。

These results suppose that niacin prorates reverse cholesterol transport by increasing ABCG5 and CYP7α expression which is stimulated by LXRα.

烟酸可能通过上调体内肝X受体α，从而刺激三磷酸腺苷结合盒转运体G5、胆固醇7α羟化酶表达来发挥促进小鼠体内胆固醇逆转运作用。

Objective To investigate in Chinese population the relationship between GTP cyclohydrolase 1 gene mutation and phenotypes of dopa-responsive dystonia.

目的 分析国人多巴敏感性肌张力障碍患者三磷酸鸟苷环羟化酶1（GCH-1）基因突变与表现型的关系。

The electron transfer chain system locates in the inner membrane of mitochondria and is made up of four large trans-membrane protein complexs, ubiquinone and cytochrome c, which is coupled with Complex V, forming the mitochondrial oxidation-phosphorylation system, producing most of the energy.

呼吸链的功能是进行生物氧化，并与称之为复合物 V 的 ATP 酶偶联，共同完成氧化磷酸化制造生物能量分子 ATP 的功能。

The activities of three oxidases were significantly lower in model group than the sham operation group. Whereas the change in preischemia group was not apparently detec-ted.

结果 缺血模型组动物的呼吸控制率、磷氧比及氧化磷酸化效率均较假手术组有不同程度的降低，3种氧化酶的活性亦较假手术组明显降低。

Moreover, Fyn kinase directly phosphorylated LKB1 on tyrosine 261 and 365 residues, and mutations of these sites resulted in LKB1 export into the cytoplasm and increased AMPK phosphorylation.

这是&能量主开关&磷酸化腺苷酸活化蛋白激酶在它们脂肪和肌肉组织中含量较少的结果。这些发现显示，这种酶有可能帮助开发一种减肥新药。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新