磷酸

Second, the solthe solthe sol-gel solution did not contain alcohol, instead, poly methyl methacrylate, aniline and phosphate salt(calcium phosphate dibasic, manganese phosphate or zinc phosphate) were added.

第二部分是在未加入酒精的状况下，将有机高分子聚甲基丙烯酸甲酯(poly methyl methacrylate， PMMA)加入含有磷酸盐(磷酸氢钙、磷酸锰或磷酸锌)的溶胶中，并利用苯胺的催化，得到奈米级的有机-无机复合皮膜。

Overview Glycogen degradation and glycogen synthesis are controlled both by allosteric regulation and by hormonal control.

变构控制和共价修饰磷酸化酶存在有磷酸化的活性 a 型河渠磷酸化的正常情况下无活性的 b 型。

Glycogen degradation and glycogen synthesis are controlled both by allosteric regulation and by hormonal control.

糖原分解及合成的主要酶是磷酸化酶及糖原合成酶，它们的活性是受磷酸化和去磷酸化的共价修饰调节及变构效应的调节。

Histamine deficiency markedly potentiated the acquisition of learning in cued and contextual fear conditioning in the HDCKO mice,but had no effect on cued and contextual fear extinction.However,histamine deficiency potentiated the inhibitory role of morphine withdrawal in cued fear extinction.Consistent with the behavioral results,morphine withdrawal decreased ERK phosphorylation in the amygdala and mPFC but not in the hippocampus of WT and HDCKO mice,and ERK might not be phosphorylad in the amygdale and mPFC of HDCKO mice after the 4th training of cued fear extinction.

但HDCKO小鼠增强了吗啡戒断对线索恐惧记忆消除的抑制作用，与行为学实验结果相一致是，，吗啡戒断能明显降低WT和HDCKO小鼠在线索恐惧记忆消除第4次训练后杏仁核和mPFC脑区的ERK磷酸化水平，但对海马脑区的ERK磷酸化没有作用；HDCKO小鼠在线索恐惧记忆消除训练的第4次训练后杏仁核、mPFC脑区的ERK蛋白没有明显磷酸化激活。

PCF significantly abolished activation of JNKs and p38 kinase activation while enhanced ERKs activation.

PCF还能提高磷酸化ERK的活性但降低磷酸化JNK及磷酸化P38的活性。

Thymocytes were also pretreated with or without ERKs, JNKs and p38 kinase inhibitors prior to UVB irradiation and DNA fragmentation was assessed by agarose gel electrophoresis. The activation of ERKs, JNKs, p38 kinase were investigated by western-blot.

透射电镜观察细胞超微结构的改变；琼脂糖凝胶电泳观察各组不加入或分别加入ERK抑制剂、JNK抑制剂和P38抑制剂后的DNA ladder；western-blot检测磷酸化ERK、磷酸化JNK、和磷酸化P38的活性。

On the other hand, fertilizer of CaHPCu is cheap and the high degree of purity (the content of P_2O_5 is 27 -30%)can improve phosphorus in soil, reduce production cost and promotes agricultural effectiveness. The content P in CaHPO_4 slow release in calcareous soil. Besides, the addition of HA activates phosphorus in CaHPO_4 and in soil, increases organics in soil, which promotes crops quality and yield.

一方面由于磷酸氢钙的纯度高，与过磷酸钙相比重金属等杂质含量较少，能有效减少对土壤及水体的污染；另一方面磷酸氢钙价格低廉，P_2O_5，含量可以达到27～30%，在石灰性土壤中本身就是一种缓效磷；腐植酸的添加，活化了磷酸氢钙中的枸溶磷，同时可能改善了土壤团粒结构，为作物优质、高产奠定了良好的基础。

RESULTS: Alkaline phosphatase activity: Alkaline phosphatase staining of cells was apparent; gray-black particles or massive precipitations were observed in cytoplasm after positive reaction; regions expressing alkaline phosphatase activity were brown-black.

结果：①碱性磷酸酶活性：经诱导后细胞碱性磷酸酶染色明显，胞质中刚性反应呈现灰黑色颗粒或块状沉淀，碱性磷酸酶活性部位呈棕黑色。

Protein phosphatases are crucial for cell living. Protein phosphatase 2A (PP2A) is an important member of serine/theronine protein phosphatase family, which is involved in almost all biological processes in eukaryotic cell. The 3D structure of PP2A core enzyme and holoenzyme was solved in 2006. These results are significant instructions for us to further understand PP2A structure, interactions between PP2A subunits, and also interactions between PP2A and its binding proteins.

蛋白磷酸酶在细胞的生命活动中起着十分重要的作用，蛋白磷酸酶2A(protein phosphatase 2A， PP2A)作为蛋白磷酸酶家族中十分重要的一员，它几乎与所有真核细胞的生命活动都有密不可分的关系。2006年，PP2A核心酶和全酶晶体结构的陆续破解对于深入了解PP2A自身的结构和亚基之间的相互作用，以及其与结合蛋白作用的机制都有重大的影响。

1、Cur inhibits K562 cells growth and induces cell apoptosis may be correlated with the down-regulation of p210~、inhibition of protein tyrosine phosphorylation and the signaling molecules such as p-Erk1/2、c-myc which are relevant with cell growth and apoptosis; 2、Cur synergizes STI571 to inhibit K562 cell growth and induce cell apoptosis may be correlated with the down-regulation of p210~、inhibition of protein tyrosine phosphorylation and the signaling molecules such as Hsp90、PKC which are relevant with cell growth and apoptosis; 3、Cur reverses the resistance of K562/G01 cells to STI571, and synergizes STI571 to inhibit K562/G01 cell growth and induce cell apoptosis; 4、Cur inhibits human originated CML CD34~+ cell growth、induces cell apoptosis, and enhances STI571 to down-regulate the expression of p210~, finally inhibit cell growth and induce cell apoptosis.

从以上实验结果我们得出如下结论： 1、Cur抑制K562细胞增殖、诱导细胞凋亡的作用可能与其下调p210~、蛋白酪氨酸磷酸化水平以及抑制下游p-Erk1/2、c-myc等信号分子有关； 2、Cur协同STI571抑制K562细胞增殖、诱导细胞凋亡的作用可能与其下调p210~、蛋白酪氨酸磷酸化水平以及抑制Hsp90和下游PKC等信号分子有关； 3、Cur可逆转K562/G01细胞对STI571的耐药性，并与STI571协同抑制K562/G01细胞增殖和诱导凋亡，其抑制K562/G01细胞增殖、诱导细胞凋亡的作用可能与其下调p210~、蛋白酪氨酸磷酸化水平以及抑制下游Procaspase-3和NF-κB等信号分子有关； 4、Cur可抑制来源于CML患者骨髓的CD34~+细胞的增殖并诱导其凋亡，还可协同STI571下调CML CD34~+细胞p210~表达，进而协同抑制细胞增殖、诱导细胞凋亡。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。