磷酰胺

In the study,the different doses of Yin Te Kang were feeded to the animals firstly.Then they were ig Cy-clophosphamide,which can cause the damage of myelic nucleus.

先用不同剂量的茵特康给实验动物灌胃，再给动物腹腔注射环磷酰胺，致骨髓细胞核/染色体损伤。

Methods Four patients with chronic myeloblastic leukemia and 4 with acute myeloid leukemia received allo-BMT with graft from 1 - 3 HLA-mismatched related donors.

方法4例慢性粒细胞白血病和4例急性髓性白血病患者接受人类白细胞抗原1-3个位点不相合骨髓移植，用阿糖胞苷、环磷酰胺和全身照射或马利兰进行预处理。

Osthole could increase the level of serum testosterone and enhance expression of peritubular myoid cefls AR in the reproduction system disturbance mice.

蛇床子素可升高环磷酰胺致生殖系统损伤小鼠血清睾酮含量的降低；增强睾丸肌样细胞AR的表达。

The sexual organ coefficents were calculated. Results: The high dose of osthole significantly increased the level of serum testosterone in the reproduction system disturbance mice and increased significantly the AR positive cells percentage of peritubular myoid cells. The low and high doses of osthole significantly increased the coefficients of seminal vesicle.

结果：蛇床子素高剂量可显著升高环磷酰胺致生殖系统损伤雄性小鼠血清中睾酮的含量(P.05)，免疫组化结果显示，高剂量可增加睾丸肌样细胞AR阳性细胞表达百分率，高、低剂量可增加精液囊的脏器系数。

We observed that cyclophosphamide-immunosuppressed adult mice were Susceptible to acute infection leading to death.4-8 week old C57 mice or outbred Kunming strain mice inoculated in-tracerebrally with HFRS virus A-16 strain and immunosuppressed with four 50mg/kg CY doses at days -1,+1,+ 2,+ 4 (day O:virai infection), developed a lethal disease94% m...

在第-l、+1，+2、+4天注射环磷酰胺50mg/kg体重(第0天感染病毒)，可使小鼠由隐性感染变为急性致死性感染，病死率为94％。在病死动物的脑，肺、肝、脾和肾等器官中，检查翻HFRS病毒抗原。这些器官显示微血管系统和实质组织的病变。这种成龄鼠模型可用于本病的研究。

Methods One injection was performed intra peritoneally with GAD purified from pig brain, together with Freund incom plete adjuvents, into female NOD mice at the age of 4 weeks as treated gro up (n=32), other 19 mice were injected FIA 100 μl alone as control group.

用猪脑GAD和不完全弗氏佐剂混合后给4周龄雌性NOD小鼠腹腔注射(32例)，同时单独注射等量FIA作为对照组。8周龄时腹腔注射环磷酰胺以加速糖尿病。

MethodsThe transplanted tumor model of the mouse S180 sarcoma was established.Fifty mice were randomly divided into five groups,the control group,the CTX group,the Gecko group.They were treated respectively with oral administration of saline,and intraperitoneal injection of CTX 100 mg/kg only one time,oral administration of Gecko in doses of 13.5,9,4.5 g/kg,one time a day.After 14 days,the anti-tumor activity was evaluated by tumor tissue weighing. The impact on immune organ was detected by accounting thymus index, spleen index and the number of peritoneal macrophage which phagocytose chicken red blood cells.The protein express of vascular endothelin growth factor and basic fibroblast growth factor were detected by SABC immunohistochemistry.

方法建立移植瘤小鼠S180肉瘤模型，将50只雌鼠随机分为对照组、环磷酰胺组、壁虎高组、中组、低组共5组，分别给于生理盐水灌胃1次/d，CTX（100 mg/kg）腹腔注射1次，壁虎高、中、低组（13.5，9，4.5 g/kg），每天灌胃1次。14 d后，称取荷瘤小鼠瘤重、胸腺重、脾脏重，计算抑瘤率、胸腺指数、脾脏指数，观察腹腔巨噬细胞吞噬鸡血红细胞实验指标；用SABC免疫组化法检测血管内皮生长因子、碱性成纤维细胞生长因子的蛋白表达，TUNEL方法检测细胞凋亡率。

Ifosfamide ; Cancer chemotherapy ; Lung cancer ; Non一Hodgkin's lym- phoma

异环磷酰胺；肿瘤化疗；肺癌；非霍奇金淋巴瘤

Feasibility of tricocyst test with Tetrahymena pyriformis were evaluated by serial chemicals (Cu2+, Cr2O2-4,Cd2+,MMC, CP, Colchicine). There is no significant difference between control and treated groups with negative chemical (Cu2+).

应用致突变阴性、阳性对照(Cu2+， Cr2O2-4， Cd2+，丝裂霉素MMC，环磷酰胺CP，秋水仙素Colchicine)评价四膜虫刺泡发射实验方法的可行性，并应用该方法检测稀土金属离子La3+，Ce3+， Sm3+， Y3+， Gd3+对四膜虫刺泡发射的影响效应。

The polysaccharide of Gloipeltis furcata could bate puny core ratio and sperm abnormalityratio arose by CP and the polysaccharide had the visible function in restrainability of the mutation.

海萝多糖对由环磷酰胺诱发的微核率和精子畸形率也有着显著的抑制作用，具有很好的抗突变作用。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。