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The flower extract of Sesamum indicum L. could significantly improve the immune function in immune-suppressed mice.

脂麻花醇提取物能明显改善环磷酰胺所致免疫功能低下模型小鼠的免疫功能。

Study on the inhibition effect mechanism of Sorbaria sorbifolia chloroform extract in S_180 mice.

珍珠梅氯仿提取物对S_(180)荷瘤小鼠抑瘤作用机制的研究取60只小鼠复制S_(180)荷瘤模型,随机分成5组:珍珠梅氯仿提取物大、中、小剂量组,对照组,环磷酰胺组。

Objective: To perform a preliminary study on the dysfunction of spermatogonial stem cells induced by cyclophosphamide.

目的:初步探讨环磷酰胺对精原干细胞分化功能的干扰作用。

Tang X, Gao J, Wang Y, et al. Effective protection of Terminalia catappa L.leaves from damage-induced by carbon tetrachloride in liver mitochondria[J].

本实验观察到环磷酰胺低、中剂量组的小鼠肝脏线粒体中VDAC的转录水平较对照组有所下降,而高剂量组则略高于正常对照组。

RESULT:Jinkui Shenqi Pill has good antagonizing effect for DNA damage caused by cyclophosphamide.

结果:金匮肾气丸对由环磷酰胺所致DNA损伤具有良好的拮抗作用。

ABSTRACT:Objective To investigate the influence of Angelica sinenisis injection on bone marrow histology and ultrastructure in mice damnified by cyclophosphamide.

目的 探讨当归注射液对环磷酰胺损伤小鼠骨髓细胞组织形态及超微结构的保护作用。

In 16 month- aged mice, TP (50, 200mg/kg, ig) also showed potentiating effect on PFC response.

TP(200,400mg/kg,ig)可促进正常小鼠的PFC反应,并可对抗环磷酰胺(10mg/kg ip)和冷水(14±1℃)游泳应激所致的PFC反应降低;TP(50.200mg/kg)可使16月龄老年小鼠低下的PFC反应恢复至正常3月龄年轻小鼠水平。

Methods Enzyme biochemical techniques is used to study the effect of berbamine and batiolˉun in the process of inceasing leukocyte and also to study the effect of LDH metabolizability.

采用酶细胞化学方法,对两种药物在治疗由免疫抑制剂环磷酰胺所致的白细胞减少症时,对乳酸脱氢酶活性的影响进行了比较观察。

The mutagenicity of seed powder and seed oil of transgenic CryIA cotton to mammals and fish was evaluated in this study. The raw cotton seed powder or seed oil was mixed into mice and fish's diet. Cyclophosphamide and NaF were used as positive controls respectively. Regular cotton seed powder and seed oil were used as negative controls. The micronucleus frequency in mice bone marrow polychromatic erythrocytes and in eripheral erythrocytes of Zebrafish were assayed in this study. The sperm malformation rate in mice was also investigated.

摘 要:分别以环磷酰胺和氟化钠作为阳性诱变剂,以普通棉的棉籽粉及棉籽油作为对照物,同时设阴性对照组,以成年封闭群昆明种雄性小鼠和斑马鱼为实验材料,将棉籽粉或棉籽油掺入饲料中饲喂小鼠或斑马鱼,检测小鼠骨髓嗜多染红细胞(Polychromatic erythrocytes, PCE)微核率(Micronucleus frequency, MN‰)和精子畸变率,以及斑马鱼外周血红细胞微核率。

The mutagenicity of seed powder and seed oil of transgenic CryIA cotton to mammals and fish was evaluated in this study. The raw cotton seed powder or seed oil was mixed into mice and fish's diet. Cyclophosphamide and NaF were used as positive controls respectively. Regular cotton seed powder and seed oil were used as negative controls. The micronucleus frequency in mice bone marrow polychromatic erythrocytes and in eripheral erythrocytes of Zebrafishwere assayed in this study. The sperm malformation rate in mice was also investigated.

分别以环磷酰胺和氟化钠作为阳性诱变剂,以普通棉的棉籽粉及棉籽油作为对照物,同时设阴性对照组,以成年封闭群昆明种雄性小鼠和斑马鱼为实验材料,将棉籽粉或棉籽油掺入饲料中饲喂小鼠或斑马鱼,检测小鼠骨髓嗜多染红细胞(Polychromatic erythrocytes, PCE)微核率(Micronucleus frequency,MN‰)和精子畸变率,以及斑马鱼外周血红细胞微核率。

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