磷酰氯

A reaction pathway for ammonolysis of O,O-dimethylphosphorochloridothioate without catalyst was proposed,based on the reaction mechanism of acyl halide ammonolysis ,and the pseudo-homogeneous reaction kinetics were founded.

模型表明：在反应前期，O，O-二甲基硫代磷酰氯浓度对速率影响很小，反应速率呈拟一级反应特征；但在反应后期，反应速率呈明显的二级反应特征。

In the reaction of NAE18 with nitrogen mustard aryl phosphorochloridate, 4-dimethylaminopyridine played critical catalytic action.

在合成工作中发现：在NAE18与氮芥芳基磷酰氯的反应过程中， 4-二甲氨基吡啶起着关键性的催化作用。

When m types of trimethylsilyl derivatives of amino acids were mediated by o- phenylene phosphorochloridate,〓/m-1 types of heterogeneous polypeptides could be obtained.

当m种三甲基硅基保护的-α-氨基酸与O，O-亚苯基磷酰氯反应时，能得到一系列不同组合、非均一的〓种2～n聚多肽。

Products: 3 - benzoyl-ethyl acrylate (97% min), acyl phosphorus acid methyl ester (98% min), P acyl three ethyl acetate (98% min), a phosphorus acid acyl The ethyl esters (98% min), 3 - bromine -1,3,4,5 - tetrahydrocannabinol -2 H-1-benzo-Aza Zhuo -2, 1 - naphthalene-tetrahydrocannabinol (98% min), 3,5 - dimethyl benzoyl chloride (99% min), 3,5 - dichloro benzoyl chloride (97% min), the ethyl benzoyl chloride (99% min), a TCA Ester (99.5% min), o-benzoyl methyl benzene (99% min), 4 - phenyl benzophenone (99% min): glacial acetic acid (99% min), methanol (99% min), liquid chlorine (99.5% min), caustic soda (30% min), isopropyl alcohol (99% min), anthranilic acid (99% min), dichloroethane (99% min ), Chunben (99% min), toluene 99% min

3-苯甲酰基丙烯酸乙酯（97%min）、磷酰基乙酸三甲酯（98%min）、磷酰基乙酸三乙酯（98%min）、磷酰基乙酸甲酯二乙酯（98%min）、3-溴-1，3，4，5-四氢-2H-1-苯并氮杂卓-2酮、1-四氢萘酮（98%min）、3，5-二甲基苯甲酰氯（99%min）、3，5-二氯苯甲酰氯（97%min）、对乙基苯甲酰氯（99%min）、氯乙酸甲酯（99.5%min）、邻苯甲酰基苯甲酸甲酯（99%min）、4-苯基二苯甲酮

Similarly, 5TPS-AVB〓 or 5-TPS-IVB〓 reacted with carbamino chloride or phosphoryl chloride in IM/DMAP system to produce six new 4"-carbamates or 4"-phosphorylates in good yields.

LA-47与氨基甲酰氯和磷酰氯反应，得到3个对应的5-4-TPS-AVB〓氨基甲酸酯或膦酸酯衍生物，产率良好。

The experiments showed that polypeptides were formed by self-assembly of N, O- bis amino acids with the assistance of o-phenylene phosphoro- chloridate. Three steps were involved in the self organization reactions, i.

侧链无官能团的N，O-二-α-氨基酸在O，O-亚苯基磷酰氯辅助下能自组装得到系列2～n聚寡肽，其自组装成肽过程大致分为三步：氨基酸的活化、肽链的延长和链反应终止。

Dialkyl phosphochloridates were used to synthesize N-phosphoamino acids in mixed aqueous media in one-step, which was applicable to a broad of amino acids, such as basic, acidic or neutral amino acids.

三、发现了用磷酰氯的方法可以在水体系中一步合成磷酰化氨基酸，适用于酸、碱和中性各类氨基酸。

In order to check the corresponding compound at 31P NMR –45.4 ppm, stable pentacoordinate spirobicyclic 2-phenoxy-1,3-phenylene-dioxo-1,3,2-iminoacetoxyphosphoranes were synthesized through a new and efficient method whereby phosphorus pentachloride was displaced stepwise by catechol, N,O-bisamino acid and phenol, or catechol, phenol and N,O-bisamino acid, their 31P NMR chemical shifts are at about 31P NMR –45.0 ppm, the results showed that the compound 4 at 31P NMR –45.4 ppm was pentacoordinate phosphorane containing amino acid residue.

采用磷谱跟踪来研究上述成肽反应机理。例如在氮气保护下，0.1mmol O，O-亚苯基磷酰氯（1）和0.15mmol N，O-二苯丙氨酸（2）苯溶液加入0.6ml核磁管中，混合均匀，反应过程用磷谱检测。反应1分钟后，起始原料1(δp=19ppm)很快转变成N-磷酰苯丙氨酸的三甲基硅基酯（3）(δp=19.8ppm)，在8分钟内，3完全转变成苯丙氨酸磷烷4(δp =-45.4ppm)，同时出现环磷三酯（6）(δp=3.5ppm)。随着反应的进行，对应于化合物4的峰逐渐变小，而6逐渐变大。

Diethylthiophosphoryl chloride was synthesized by reacting phosphorus thiochloride with anhydrous alcohol in the presence of NaOH, and then a novel phosphorus-nitrogen- and sulfur-containing flame retardant, 1, 4-di(O,O-diethyl thiophosphoryl imine) benzene, was synthesized via the reaction of diethylthiophosphoryl chloride with p-phenylenediamine.

以三氯硫磷与无水乙醇在NaOH存在下合成了二乙基硫代磷酰氯，然后再与对苯二胺反应合成了新型的含磷、氮、硫的膨胀型阻燃剂：1，4-二（O，O-二乙基硫代磷酰亚胺基）苯。

With the aid of 〓P NMR examination for the process and ESI-MS/MS analysis of the derivatized products from the reaction intermediate, it is found that the corresponding phosphoryl chloride is generated after mixing the hydrogen phosphonate derivative with chlorodiisopropylamine, and they react with amino acid, amino acid methyl ester, dipeptide methyl ester or N-methyl imidazole carboxyl alkyl diamine respectively to form the desired products.

利用〓P NMR对反应过程监测以及对反应中间体衍生化后产物的ESI-MS／MS检测分析发现，氢亚磷酸二酯与氯代二异丙胺反应首先生成了磷酰氯中间产物，它继续与氨基酸、氨基酸甲酯、二肽甲酯、1-甲基咪唑-2-酰基烷基二胺等反应生成了目标产物。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。