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We used phospholipid, Epikuron 200, and cholesterol as material to prepare liposome formulation, and discuss the effect of liposome formulation which contain phospholipid and cholesterol or the mix of ionic surfactants such as stearylamine, dicetyl phosphate and nonionic surfactant such as Tween 80. For the three group that physical properties of drug entrapment efficiency, particle size and stability of formulation on day 0, 14, 21 and 30 were respectively compared, and further, we were sieve out optimization of formulation.

我们利用Epikuron 200之磷脂质,以及胆固醇作为制备微脂粒处方之材料,并探讨处方不加或分别加入表面修饰剂stearylaminem与dicetyl phosphate以及非离子界面活性剂Tween 80对处方之影响,且比较此三组微脂粒的物理性质,包含包埋率、粒径大小以及处方在第0、14、21、30天之安定性的变化,进一步筛选出理想之处方。

The development of Chinese herbal medicine is one of main methods for peasants to increase income in the eastern mountain area of Liaoning.The main medicinal plants in Liaoning Province are schisandra,asarum,dioscorea, panax,gentiana,aconitum,fritillaria,lilium,astragalus,saposhnikovia,atractylodes,polygonatum, clematis,dictamnus,etc.The soils of nearly 20 species of the medicinal plant were studied in this paper.The differences among different medicinal plants were analyzed.The species and quantity of fungi,bacteria and antinomycete in soil of medicinal plants were clear.With the pathogen of main diseases of medicinal plants as target,the strains in the control of pathogen were screened from soil of medicinal plants.

在本研究中,首次以辽宁省主栽药用植物:五味子、细辛、穿山龙、移山参、龙胆、黄花乌头、平贝母、百合、黄芪、防风、苍术、玉竹、威灵鲜和白鲜皮等近20种药用植物土壤为研究对象,应用平板稀释法和磷脂脂肪酸测定法对土壤微生物多样性进行研究,通过研究明确了影响土壤微生物多样性的因素;土壤微生物与药用植物关系;以药用植物土壤微生物为供试菌株,药用植物近年来主要病害为靶标菌,进行生防菌株筛选。

Hematoxylin alcoholl extracts with different concentration were co-cultured with lung cancer A549 cells in order to observe effects on cell proliferation by using MTT method, study the effects on cytotoxicity and apoptosis of lung cancer A549 cells using optical microscope, phosphatidylserine ecstrophy analysis and cell period analysis.

将苏木醇提物按不同浓度分别同人肺癌A549细胞共同培养,MTT法检测对细胞增殖作用的影响,光学显微镜、细胞膜磷脂酰丝氨酸外翻分析、细胞周期分析观察不同浓度苏木醇提物对人肺癌A549细胞的细胞毒和调亡作用。

Thus, GPC6 seems to have a previously unsuspected role in endochondral ossification and skeletal growth, and its functional abrogation results in a short-limb phenotype.

因此,磷脂酰肌醇蛋白聚糖 6在软骨内骨化和骨骼肌发育中发挥着以前未曾发现的重要作用,并且其是短肢体表型不能发挥正常功能的主要因素。

The results showed that PLA2, and lipid peroxide may be the causes of the changes of proton translocation in endotoxic shock rats.

可能膜脂质过氧化和磷脂酶A2的水解是引起内毒素休克肝线粒体质子转运功能改变的重要因素。

Mammary gland epithetical cells were taken to analyze the phospholipids ingredients. SDS-Polyacrylamide gel electrophoresis was used for analyzing the membrane protein ingredients. ATPase activities which have important function in mammary protein were also tested.

同时提取乳腺上皮细胞膜,检测了乳腺上皮细胞膜磷脂组分的相对百分含量,并对膜蛋白进行了SDS-PAGE电泳,蛋白质凝胶成像系统对电泳条带进行定性定量分析,对膜蛋白中具有重要功能的ATP酶的活性进行了测定。

OBJECTIVE To investigate the effects of extracorporeal circulation on anticardiolipin antibody before and after operation and its clinical significance.

目的探讨体外循环对抗心磷脂抗体(anticardiolipin antibody ACL-Ab)的影响及其意义。

Result: Glutin could make the absorption of jatrorrhizine, coptisine, berberine and total alkaloids increased by 30%. Tween 80 and arabic gum did not affect the absorption of berberine, but inhibit that of other alkaloids. There had no influence of lecithin on the absorption of alkaloids.

结果:明胶使药根碱、黄连碱、小檗碱和总生物碱的吸收均提高约30%;聚山梨醇酯和阿拉伯树胶对小檗碱的吸收无影响,而抑制其他3种生物碱和总碱的吸收;卵磷脂几乎不影响各生物碱的吸收。

The mean conˉcentrationsof the total bile acid in the gallbladders were respectively77.53±11.93,51.81±8.12and53.27±7.04in group DM,CH and DMCH,but it was79.28±18.28in group N.Combined bile acids(both glycocholic acid and taurocholic acid)were apparently lessened and the ratio of cholic acid and chenodeoxycholic acid was rised in group DM,CH and DMCH,the concentrationsof cholesterol were respectively5.31±0.81,5.69±2.20and5.12±1.47,but0.86±0.20,in the group N;those of phospholipd were respectively0.35±0.16,0.52±0.18and1.38±0.34,but0.59±0.28,group N.

胆囊胆汁成分分析中,DM组、CH组和DMCH组总胆汁酸分别为77.53±11.93、51.81±8.12和53.27±7.04,N组为79.28±18.28;与N组比较结合胆汁酸减少,其中甘氨胆汁酸盐与牛磺胆汁酸盐均减少;鹅去氧胆酸减少,胆酸/鹅去氧胆酸比值升高;胆汁胆固醇分别为5.31±0.81、5.69.20和5.12±1.47,N组为0.86±0.20;磷脂分别为0.35±0.16、0.52±0.18和1.38±0.34。

Stones were seen in the gallbladder of12/12cases in either group DM and CH,and11/12in the group DMCH.The mean conˉcentrationsof the total bile acid in the gallbladders were respectively77.53±11.93,51.81±8.12and53.27±7.04in group DM,CH and DMCH,but it was79.28±18.28in group N.Combined bile acids(both glycocholic acid and taurocholic acid)were apparently lessened and the ratio of cholic acid and chenodeoxycholic acid was rised in group DM,CH and DMCH,the concentrationsof cholesterol were respectively5.31±0.81,5.69±2.20and5.12±1.47,but0.86±0.20,in the group N;those of phospholipd were respectively0.35±0.16,0.52±0.18and1.38±0.34,but0.59±0.28,group N.

胆囊胆汁成分分析中,DM组、CH组和DMCH组总胆汁酸分别为77.53±11.93、51.81±8.12和53.27±7.04,N组为79.28±18.28;与N组比较结合胆汁酸减少,其中甘氨胆汁酸盐与牛磺胆汁酸盐均减少;鹅去氧胆酸减少,胆酸/鹅去氧胆酸比值升高;胆汁胆固醇分别为5.31±0.81、5.69.20和5.12±1.47,N组为0.86±0.20;磷脂分别为0.35±0.16、0.52±0.18和1.38±0.34。

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