磷胺

The results indicated that the pesticide could be distributed through the body and cumulated in peripheral compartment relatively,but it could be eliminated rapidly.With parameters such as t1/2α valued 3.40min,t1/2β 59.03min and Cl 0.018ml·min-1,Its metabolism followed two-compartment open model after administration of 10 mg/kg.It was primary distributed to blood-riched organs and fat tissues and ready to be biotransformed.The metabolic product were detected in choler,which had stronger polarity with retention time 4.25min;and no parent compound was found in both urine and faeces.Key words: Toxicokinetics;Fenamithion;Organophosphorus pesticide

结果显示：螨胺磷在体内全身分布，并有周室富集，消除较快，在10mg/kg静脉注射呈二室模型，t1/2α为3.40min，t1／2β为59.03min，全身清除率Cl0.018ml·min-1；螨胺磷主要分布于血流量大的器官及脂肪组织；螨胺磷在体内不稳定，能被肝脏代谢转化成极性更高的化合物后经由胆汁排出，该成分可在同样的色谱条件下被分离，峰保留时间4.25min；粪尿中均未检出原药。

A sequential extraction technique to fractionate P and the method proposed by Bremner to separate N in different fractions were used.

本试验利用Sui 和 Thompson (1999)序列萃取法，以不同强弱的萃取剂来划分土壤中的磷，将土壤磷划分为水萃取磷、碳酸氢钠萃取有机磷及无机磷、氢氧化钠萃取有机磷及无机磷、盐酸萃取磷及残余磷；利用 Bremner (1965)的土壤有机态氮划分法将土壤有机态氮划分为水解性全氮、水解性铵态氮、胺基醣态氮、胺基酸态氮及不可辨认的水解性氮。

Our company supply raw materials and related intermediates as follows: Second dibutyryl cAMP calcium, voriconazole, terbinafine, vecuronium amines, cAMP, thiamphenicol, a chlorophenol hydrochloride esters, card network sodium phosphate tilmicosin, foscarnet, lornoxicam, Tilmicosin, Cephalosporium aspirin acid, ceftiofur hydrochloride, ceftiofur sodium, Ozagrel, ondansetron hydrochloride ketones, hydroxyurea, ticarcillin sodium, telmisartan, esmolol hydrochloride, hydrochloric acid Daguan Nikkomycin, adefovir dipivoxil, buflomedil hydrochloride, granisetron hydrochloride, warfarin sodium,-methyl gabexate acid, nicergoline, pantoprazole sodium,·, tegafur, cefepime hydrochloride, vecuronium bromide, hydrochloric acid meclofenoxate, sertraline hydrochloride, Cefonicid amine salt, aztreonam, ticarcillin, cefdinir, cefodizime sodium, sodium ferulate, colloidal pectin secretion, 2,3 - cyclopentene and pyridine, Piperacillin acid, cefetamet US-acid, hydrochloride Cefmenoxime ,3-TZ, 2 - deoxy-D-glucose, two-amidine urea benzene, sodium Cefonicid, Cefonicid intermediates, ester Cefamandole sodium, Cefalotin acid, intermediates cefpirome, cefepime sulphate, cefepime intermediate nucleus of cefepime, cefpirome nucleus, Cefamandole sodium, ceftriaxone new active ester, oxaliplatin, cyclophosphamide vary gland amines, polyene match him.

我公司供应的原料药及相关中间体为：二丁酰环磷腺苷钙、伏立康唑、盐酸特比萘芬、维库溴胺、环磷腺苷、甲砜霉素、盐酸甲氯酚酯、卡络磺钠、磷酸替米考星、膦甲酸钠、氯诺昔康、替米考星、头孢匹胺酸、头孢噻呋盐酸盐、头孢噻呋钠、奥扎格雷、盐酸恩丹西酮、羟基脲、替卡西林钠、替米沙坦、盐酸艾司洛尔、盐酸大观霉素、阿德福韦酯、盐酸丁咯地尔、盐酸格拉司琼、华法林钠、甲磺酸加贝酯、尼麦角林、泮托拉唑钠、普拉洛芬、替加氟、盐酸头孢吡肟、维库溴铵、盐酸甲氯芬酯、盐酸舍曲林、头孢尼西胺盐、氨曲南、替卡西林、头孢地尼、头孢地嗪钠、阿魏酸钠、胶体果胶泌、2，3-环戊烯并吡啶、哌拉西林酸、头孢他美酸、头孢甲肟盐酸盐、3-TZ、2-脱氧-D-葡萄糖、双脒苯脲、头孢尼西钠、头孢尼西中间体、头孢孟多酯钠、头孢噻吩酸、头孢匹罗中间体、头孢吡肟硫酸盐、头孢吡肟中间体、头孢吡肟母核、头孢匹罗母核、头孢孟多钠、头孢曲松新型活性酯、奥沙利铂、异环磷腺胺，多烯他赛。

Results: The extract of propolis had certain antineoplasm effect and the inhibition rate of propolis extract on tumor is 27.74％ and when combined with cyclophosphamide, the inhibition rate reached to 50.32％, even antagonized leucocytopenia caused by cyclophosphamide.

结果：蜂胶提取物的抑瘤率为27.74％，与环磷酰胺合用的抑瘤率为50.32％，比单用蜂胶提取物及环磷酰胺分别提高22.58％和9.03％(P＜0.05)，并能减轻环磷酰胺所致的骨髓造血功能抑制，使血液白细胞维持在正常水平(P＜0.01)。

Methamidophos affected the mean ratio of ovigerous to non-ovigerous females and the mean mictic rate significantly but had less effect on the total resting egg production, while 17β-estradiol was in adverse.

甲胺磷和17β-雌二醇对实验期间轮虫的平均种群增长率均有显著影响，但对轮虫种群中的混交雌体受精率的平均值无显著影响；甲胺磷对实验期间轮虫种群中的携卵雌体数／非携卵雌体数和混交雌体百分率的平均值均有显著影响，而17β-雌二醇则无显著影响；甲胺磷对实验期间轮虫的休眠卵总产量无显著影响，而17β-雌二醇的影响较显著。

Two types of P Br N contained flame retardant,O (2,4,6 1 trioxo 1 oxyphosphabiscyclooctane 4 methylene) O (2,3 dibromopropyl)phosphoric melamine salt and O (2,4,6 tribromophenyl)phosphoric melamine salt,were synthesized from phosphorus oxychloride,pentaerythritol,2,3 dibromopropanol,2,4,6 tribromophenol and melamine,etc.

以三氯氧磷、季戊四醇、2 ，3 二溴丙醇、2 ，4，6 三溴苯酚及三聚氰胺等为原料合成了两种含磷溴氮阻燃剂，即O (2 ，4，6 三氧杂 1 氧基磷杂双环 [2 。2 。2 ]辛烷 4 亚甲基) O 2 ，3磷酸三聚氰胺盐和O (2 ，4，6 三溴苯基)磷酸三聚氰胺盐。

The results show that 60Co-γ ray radiation has the most remarkable effect on the degradation of organophosphorus pesticides such as fenitrothion, parathion, methyl-parathion, phorate and chlorpyrifos and the maximum degradation rates are over 85%. The degradation rates of methamidophos, acephate, malathion ,dimethoate are slightly inferior to them and the optimum degradation rates is just only 34.70%. At the same time, the contents of soluble total sugars, glucose, fructose, sucrose and total sugars in apple juice decrease unconspicuously, but the total acid content in apple juice and its color value and clarity increase. Based on a comprehensive consideration of the 60Co-γ radiation effect on the actual degradation of organophosphorus pesticides in apple juice and its main chemical and physical indexes, organophosphorous pesticides residue will be decreased to a lower level with radiation dose of about 5 kGy but the main chemical and physical indexes of export apple juice can not be affected.

结果表明： 60Co-γ射线辐照处理对苹果汁中杀螟硫磷、对硫磷、甲基对硫磷、甲拌磷、毒死蜱降解效果最为显著，最高降解率均在85%以上；对苹果汁中甲胺磷、乙酰甲胺磷、马拉硫磷和乐果的降解效果不显著，最高降解率仅为35%；在0～9 kGy辐照剂量范围内降解苹果汁中有机磷农药的同时，会使苹果汁中的可溶性固形物、葡萄糖、果糖、蔗糖及总糖含量轻微降低，苹果汁的总酸度有所增加，苹果汁的色值及透光率提高；综合分析60Co-γ射线辐照对苹果汁中有机磷农药的实际降解效果及对苹果汁主要理化指标的影响，选用5 kGy的辐照剂量已完全使苹果汁中的有机磷农药残留降低到一个很低的水平，又不会对苹果汁出口主要理化指标造成影响。

The company mainly engaged in IHF Chen Fu-chemical pump, IH chemical centrifugal pumps, IS, ISZW, ISW series of single-suction centrifugal pumps, FJX series of forced circulation pump, WB series stainless steel whirlpool pump, LJYA amine-phosphate material pump, FY-liquid pumps, GNF-screw pump, IHG, ISG, SG series of pipeline pump, CQ-magnetic pump, AY-type pumps, CPN not plug the base pumps, YL series dedicated filter pump, ZW, ZWF series without plug Self-suction pumps, DF series dedicated pump starch, FSB fluoride plastic pump, FBR temperature-pressure pump printing and dyeing, AFB series Naifushibeng, LH phosphating solution for pump, CZ series of standard chemical pump, ZH series of self-suction centrifugal pump chemicals , UHB-ZK series of mortar decay resistance wear-resistant products such as pumps, the material is: 1 Cr18Ni9Ti, 1Cr18Ni12Mo2Ti, 304,904,316,316 L, CD4MCu, K alloy, F46, PP, PE, widely used in petroleum, chemical, electric power, Printing and dyeing, environmental protection, metallurgy, food and other industries.

本公司主要经营IHF型化工衬氟泵，IH型化工离心泵，IS、ISZW、ISW系列单级单吸离心泵，FJX系列强制循环泵，WB系列不锈钢旋涡泵，LJYA 型磷胺料浆泵，FY型液下泵，GNF型螺杆泵，IHG、ISG、SG系列管道泵，CQ型磁力泵，AY型油泵，CPN无堵塞碱泵，YL系列压滤机专用泵，ZW、ZWF系列无堵塞自吸泵，DF系列淀粉专用泵，FSB氟塑料泵、FBR型耐温耐压印染泵，AFB系列耐腐蚀泵，LH磷化液专用泵，CZ系列标准化工泵，ZH系列自吸式化工离心泵，UHB-ZK系列耐腐耐磨砂浆泵等产品，材质有：1Cr18Ni9Ti、 1Cr18Ni12Mo2Ti、304、904、316、316L、CD4MCu、K合金、F46、PP、PE等，广泛应用于石油、化工、电力、印染、环保、冶金、食品等行业。

Using heptachlor epoxide as interal standard, the linearity of 28 pesticides were good with 〓 in 0.99～1. 000, except phosphamdon with 〓 at 0.963. The RSD for most pesticide were below 10％.

采用该方法，以环氧七氯为内标，29种农药中28种农药的线性关系良好，〓在0.99～1.000之间（磷胺的〓为0.963），大部分农药的RSD0％。

Tris-(1-aziridinyl)- phosphine oxide and 2-[bis-(2-chloroethyl)-amino]-tetrahydro-1, 3, 2-oxazaphospholidine-2-oxide(Ⅲ, B-518) possess inhibitory action against a variety of animal tumours and have been used clinically. Recently, bis-(1-aziridinyl)-phosphinyl carbamic acid ethyl ester(Ⅱ, AB-100) was found to possess significant activity with low toxicity on experimental animal tumours.

双(2-氯乙基)氨基磷酰二氯与乙烯亚胺在脱水苯或对氧六环中并在三乙胺的存在下进行缩合，生成N，N-双(2-氯乙基)-N′，N-二乙烯基-磷酰胺；与双巯基或双氨基化合物作用，则生成相应的环状磷酰胺、磷酰胺酯以及磷酰胺硫代酯氮芥类化合物。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。