碳粒

Pharmacodynamic action ; Xiaochaihu Oral Liquid ; Radix Bupleuri ; acute liver function damage of rat ; fever reaction of rabbit ; carbon particle clearance of mice ; delayed anaphylaxis reaction

昆明种小鼠；生理盐水；小剂量；碳粒廓清速率；小柴胡汤口服液；四氯化碳；鸡红细胞；迟发性过敏反应；角叉菜胶；药理作用

In This paper, the variation history of spray, Combustion and Soot in diesel engine under different swirl ratio were studied using flame image and shadowgraph taken synchronously.

采用双成象技术研究了不同进气涡流比时直喷式柴油机喷雾、燃烧和碳粒变化历程。

Methods: Mice bearing in vivo transplanted tumor-H22 hepatic carcinoma were used to evaluate the drug"s activity of anti-tumor and GAPSGF"s efficacy enhancing effect by calculating the ratio of antitumor and q. HE dyeing was applied to observe the tumor"s morphological changes after the anti - tumor drug. It is observed the change of theperipheral white blood cells in serum and the body weight to analyze the GAPSGF"s toxicity reducing effect on the anti - tumor drug-Cytoxan. Applying ELISA method to observe the change of IL-2 in serum ,Applying carbon clearance method to test the function of uninuclear phagocyte,took the weight of the spleen and thoracic gland, analyzed the mechanism — efficacy enhancing and toxicity reducing of GAPSGF.

构建体内动物移植性H_(22)肝癌模型，通过计算抑瘤率与q值来分析药物的体内抗肿瘤活性，判断树舌多糖GF注射液的增效作用；采用瘤组织常规HE染色观察药物作用下的肿瘤细胞形态变化；观察外周血WBC数和体重改变来分析树舌多糖GF注射液对环磷酰胺抗肿瘤的减毒作用；采用ELISA法测定血清IL-2、小鼠碳粒廓清法测定单核吞噬细胞功能、取胸腺与脾脏称重测定脏器指数等以分析树舌多糖GF注射液增效减毒的作用机制。

Methods The drymeal of Andrias daridianus was po for 28 days, and the ratio of immuno-organs index, the content of serum hemolysin, antibody-producing cells, carbon clearance index and ear-swelling extent were detected.

纯大鲵粉小鼠灌胃，检测免疫器官指数、血清溶血素含量、脾抗体细胞生产数、碳粒廓清指数、耳肿胀度，研究对小鼠免疫功能的影响。

Determination of total hydroxybenzene, extractive technology by orthogonal design and immuneological effect in way of hemolysin and carbon particle clearance determinations of Caesalpinia Sappan L.were studied for the first time.

本研究中，有关苏木中总酚含量的测定方法、苏木提取工艺的正交优选法以及采用溶血素法和碳粒廓清法对苏木提取物进行的药效学研究，至今未见报道。

The immuneological functions of watery extract, sixty-five and ninety-five percent of ethanol extracts of Caesalpinia Sappan L. in mice were studied. It was reviewed that extracts had effects on the production of hemolysin antibody by CRBC and meshy endothelium phagocytosis function in mice.

利用水、65%、95%乙醇提取物进行了免疫药效学的动物实验研究，考察了上述提取物对红细胞所致的小鼠溶血素抗体生成的影响以及小鼠网状内皮系统对血流中惰性碳粒的吞噬功能的影响。

Under inhibit tumor fall increment andalert confession The objective of this experiment is to prove the antitumor effect and its mechanism in vivo of Erysimum cheiranthoides. In this study we observe the ratio of inhibitory of mice bearing S180 and the effect of prolonging lives of mice bearing H22;the effect on immune function of mice bearing S180;the phagocytosis of MO cells; measuring serum TNF of mice bearing S180 with ELISA; the expression level of p53 in tumor tissue with ICH and the change of tumor cells shape with pathology test.

实验采用S_(180)、H_(22)两种瘤株，以昆明利，小鼠为研究对象，对体内的抑瘤作用、生命延长作用进行研究；对S_(180)荷瘤小鼠免疫功能影响的研究；采用碳粒廓清法研究该药对巨噬细胞吞噬功能影响的研究；采用ELISA法检测S_(180)荷瘤小鼠外周血TNF含量；采用免疫组化法测定S_(180)小鼠瘤组织中p53蛋白的含量并观察瘤细胞的病理形态。

METHOD: The following tests were made:①test with of hemopoietic inhibition induced by cyclophosphamide on mice,②Carban particles clearance test,③Erythrolysin formetien test,④Swimming test,⑤Hypoxia test,⑥Sedation test,⑦Hypnosis test.

①由环磷酸胺引起的小鼠造血系统抑制模型；②小鼠碳粒廓清试验；③小鼠溶血素形成试验；④小鼠游泳试验；⑤小鼠耐缺氧试验；⑥小鼠旷野活动试验；⑦由戊巴比妥钠引起的小鼠催眠模型。

ResultsCompared with model group, the clearance rate K of charcoal particles, phagocytic index a, thymus and spleen index and ear swelling degree of 80 mg/kg.bw Fortunella crassifolia flavonoid dose group were significantly improved(P.05), and a very significant effect (P.01) was made to the HC50 value at this dose.

结果与模型对照组相比，金橘黄酮80 mg/kg·bw 剂量时，小鼠碳粒廓清指数K、吞噬指数a、胸腺和脾脏指数、耳肿胀度有显著提高（P0.05），血清溶血值（HC50）有极显著提高（P.01）；金橘黄酮160 mg/kg·bw 剂量对全部试验参数的影响具有极显著性（P.01）。

MethodsThe immunosuppressed mice were induced by cyclophosphamide and Fortunella crassifolia flavonoid was taken orally. The immunodulatory effects were measured by clearance rate K of charcoal particles, phagocytic index a, thymus and spleen index, ear swelling degree, HC50 value and so on.

方法环磷酰胺诱导小鼠免疫功能低下，予金橘黄酮，观察小鼠碳粒廓清指数K、吞噬指数a、胸腺和脾脏指数、耳肿胀度、血清溶血值（HC50）等指标的变化。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。