碳二亚胺

For the advantages of mild reaction conditions,DDC condensation method and acyl chloride esterification method are much more popular.

由于具有反应条件温和的优点，二环己基碳二亚胺脱水缩合法和酰氯酯化法是目前国内外最常用的两种方法。

The result showed that 5-fluorouracil could link to the peanut agglutinin by EDC/NHS crosslinking with high drug ratio.

结果表明碳二亚胺法可成功实现药物与花生凝集素的连接，该法制备得到的结合物其药物结合率高。

Methods GAMP was activated with cyanogen bromide and combined with 1, 6-adipic acid dihydrazide. The prepared polysaccharide derivative GAMP-ADH was coupled to recombinant protein Pep10 with N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride.

GAMP经溴化氰活化后，共价接合己二酰肼手臂，在碳二亚胺催化下与重组蛋白Pep10偶联，制备结合物GAMP-ADH-Pep10。

Two artificial antigens Bz_HS_protein and Bz_SO 2_protein have been synthesized by the succinic anhydride_carbodiimide method and the sulfonyl chloride method separately.

用琥珀酸酐－碳二亚胺法和氯磺化法合成了毕兹的两种人工抗原Bz＿HS＿protein和Bz＿SO2＿protein。

The selectivity of cyclization of carbodiimide 2 with primary amine was studied and the result showed that the anomalous product being cyclized from arylamino group was formed preferencially.

研究了碳二亚胺2与伯胺成环反应的选择性，结果表明优先生成反常的芳氨基成环产物，利用中间体可能的构型解释了实验结果。

Methods: Hapten of dimethoate was synthesized, then it was conjugated to bovine sera albumin and ovalbumin to prepare immunogen and coating antigen respectively by carbodiimide method.

采用生产乐果的中间体硫磷醋与l， 4-二氨基丁烷反应合成乐果半抗原，利用碳二亚胺法，将半抗原与牛血清白蛋白及卵清蛋白偶联，分别制备免疫原和包被原。

Ferrocenecarboxylic-ssdeoxyribonucleic acid probe was made by chemically bounding FCA to terminal 5'-amino of oligonucleotide in the presence of a water-soluble carbodiimide. The hybridization reaction was conducted by immersing the immobilized-ssDNA electrode in FCA-ssDNA probe solution.

在偶联活化剂碳二亚胺的存在下，通过羧基二茂铁上的羧基与DNA分子上的氨基共价键合，将FCA标记在氨基修饰的寡聚核苷酸片段上，制备成FCA-ssDNA探针。

Was synthesized from cyanoacetic acid and diethylamine via DCC coupling under mild conditions.

中间体5 的制备由氰基乙酸在二环己基碳二亚胺作用下经酰胺化一步制得，条件温和，收率较高，避免使用剧毒的氰化钠。

Methods Activate groups A and C meningococcal polysaccharide with cyanogens bromide and prepare into MenAPS-ADH and MenCPS-ADH derivatives by reacting with 1, 6-adipic acid dihydrazine. Mix MenAPS-ADH and MenCPS-ADH derivatives with purified tetanus toxoid at a certain mass ratio, then add l-ethyl-3(3-dimethylaminopropyl)-carbodiimide to prepare bulks of MenAPS-TT and MenCPS-TT conjugates respectively. Mix the two bulks at a certain ratio, add stabilizer and lyophilize to prepare group A+C meningococcal polysaccharide conjugate vaccine.

A群和C群脑膜炎球菌多糖在溴化氰的活化下，以1，6己二酰肼作为连接子，与精制破伤风类毒素在碳二亚胺作用下结合，再按一定的比例将两者混合，制成A+C群脑膜炎球菌多糖结合疫苗原液，加保护剂冻干后，制成A+C群脑膜炎球菌多糖结合疫苗。

Two types of haptens, the earboxylated propyl amino derivative of the acid moiety (HCA1) that is the hydrolyzed product of cyhalothrin, and the carboxylated ethyl carbonyl derivative of the alcohol moiety (HCB2) were synthesized, and conjugated with the carrier proteins bovine serum albumin and ovalbumin respectively by the active ester method and the mixed anhydride method. The polyclonal antibodies were obtained after immuning to the New Zealand rabbits.

通过对氯氟氰菊酯分子结构中的酸部分接4-氨基丁酸(HCA1)和醇部分接丁二酸酐(HCB2)，合成两种不同的半抗原，并通过碳二亚胺法将HCA1和HCB2分别与牛血清蛋白偶联制备了人工抗原HCA1-BSA和HCB2-BSA，通过活泼酯法将HCA1、HCAS和HCB2分别与卵清蛋白偶联制备包被抗原，两种人工抗原通过免疫新西兰大白兔来制备相应的多克隆抗体。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。