碳二亚胺

The cis novel bisoxazoline ligands L1-L4 have been synthesized through the treatment of new cis dihydroxy diamide with p-toluenesulfonyl chloride in the presence of catalytic quantity of 4--pyridine, and the cis dihydroxy diamide could be achieved from the condensation of the amino alcohols and cis cyclopropane dicarbonyl chloride prepared via oxidation and halogenation from cis-2,2-dimethyl-3-formylcyclopropanecarboxylate with DCC.

我们以蒈醛酸内酯为起始原料，经过氧化反应、酰氯化反应得到顺式环丙烷二酰氯，然后在二环己基碳二亚胺的催化下与相应的氨基醇反应合成了顺式二羟基酰胺，再用对甲苯磺酰氯将羟基活化，最后在二甲氨基吡啶的催化下关环合成顺式双噁唑啉配体L1～L4。

A series of 3-naphthyl-2--1,3-thiazolidin-4-ones were synthesized by the three-component one-pot cyclocondensation of naphthylamine, aromatic aldehyde and 2-mercaptoacetic acid using a microwave-assisted method in the presence of DMAP/DCC.

利用微波促进的多组分一锅法，在封管条件下，以萘胺、芳醛和巯基乙酸为原料，4-二甲氨基吡啶/N，N'-二环已基碳二亚胺为催化剂，合成了系列新的噻唑烷酮衍生物，该反应具有时间短、操作简便等优点。

By means of covalent coupling with the activation of 1-ethyl-3-(3-dimethyllaminopropyl) carbodiimide hydrochloride and N-hydroxysulfosuccinimide.

利用自组装技术将三巯基丙酸固定在金电极上，以1-乙基-3-（3-二甲氨基）碳二亚胺盐酸盐和N-羟基硫代琥珀亚胺作为活化剂，将甲基对硫磷抗体以共价键形式固定在三巯基丙酸自组装单分子膜修饰的金电极上，制备了一种免疫传感器。

Further aza-Wittig reactions of iminophosphorane 3 with aromatic isocyanates gave the carbodiimide s 4, which were reacted with secondary amines to give 2-dialkylamino-thieno[2,3-d]pyrimidin-4(3H)-ones 6 in the presence of catalytic amounts of EtO-Na+ in 58%～82%.

应用膦亚胺3与芳基异氰酸酯的氮杂Wittig反应，生成的碳二亚胺4，再与仲胺作用得到中间体5，而后在醇钠的催化下关环制得2-二烷氨基噻吩并[2，3-d]嘧啶-4(3H)-酮衍生物6，产率为58%～82

Tetrachloroterephthalic acid was prepared by chlorinating terephthalic acid, oleumsolvent and iodine catalyst. Tetrachloroterephthalic acid was acylated by sulphurous oxychloride in the presence of DMF to form tetrachloroterephthaloyl chloride. The acyl chloride product was fluorinated by potassium fluoride and esterified by methanol to synthesize dimethyl tetrafluoroterephthalate. The ester was reduced with potassium borohydride and lithium chloride to give tetrafluoroterephthalyl alcohol. The above product was bromated in the hydrobromic acid to obtain 4-bromomethyl-2,3,5,6-tetrafluoro-benzene methanol. 4-Methyl-2,3,5,-6-tetrafluorobenzene ethanol was obtained by reducing the bromide with magnesium. In the exist of DCC and DMAP, tefluthrin was got by the condensation reaction between 4-methyl-2,3,5,6-tetrafluoro-benzene methanol and-(1RS,3RS)- 3-(2- chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl cycolpropanecar-boxylate acid.

对苯二甲酸与氯气在碘存在下以发烟硫酸为溶剂进行氯化制备四氯对苯二甲酸；再以DMF为催化剂与二氯亚砜反应生成四氯对苯二甲酰氯；以氟化钾为氟化剂，环丁砜为溶剂置换氟化，再与甲醇酯化得到四氟对苯二甲酸甲酯；以KBH4-LiCl为还原剂二甲醚为溶剂反应制得四氟对苯二甲基苄醇；以氯苯为溶剂在溴化氢溶液中溴化得到溴化产物；在乙醇溶液中经镁粉还原得到4-甲基-2，3，5，6-四氟苄醇；甲基苄醇与功夫酸在催化剂二环己基碳二亚胺和4-二甲氨基吡啶作用下缩合得到七氟菊酯，总收率达43.6%。

CNTs were first pre-treated using acid solution (HNO3) to obtain CNTs functionalized with carboxylic groups. Subsequently, the stearyl alcohol was grafted onto CNT with the assistance of dehydrating agent, N,N'-dicyclohexyl-carbodiimide. Excellent dispersion in organic solvents such as acetone, THF, and chloroform was found for the modified CNTs (CNT-C18). In addition, the PBS/CNTs nanocomposites were then prepared through simple melt-blending. Mechanical properties, thermal behavior, conductivity of resultant polymer/CNT composites were investigated. The results show that excellent dispersion of nanotubes in the PBS matrices was achieved.

为了增加多壁奈米碳管在复合材料中的分散性，将碳管表面进行化学修饰，首先将多壁奈米碳管浸入HNO3溶液中，进行酸化，使碳管表面带有羧酸的官能基，然后再加入十八烷醇，在温和的条件下，藉由N，N'-二环己基碳二亚胺(N，N'-dicyclohexyl- carbodiimide，DCC)脱水剂脱水，使碳管和十八烷醇之间产生酯基的化学键结，改质后的碳管可以分散在acetone、THF、chloroform…等有机溶剂中，结果显示成功的利用DCC脱水剂完成碳管的改质。

In order to improve the stability and mechanical properties in moist state,the gelatin nanofibrous membranes were chemically crosslinked by 1-ethyl-3-dimethyl-aminopropyl carbo-diimide hydrochloride and N-hydroxyl succinimide.

采用1-乙基-(3-二甲基氨基丙基)碳二亚胺和N-羟基琥珀酰亚胺对明胶纳米纤维膜材料进行化学交联处理，改善了材料的耐水性、热稳定性和力学抗拉性能。

The hydrophobic core serves as a reservoir for water-insoluble drugs.Hence,these nanoparticles can be used as carriers for hydrophobic drugs.For the synthesis of cholesterol-modified glycol chitosan conjugates,a carboxyl group was initially introduced to cholesterol molecule using succinic anhydride,and then covalently coupled with the primary amino group of glycol chitosan in the presence of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride and N-hydroxyl succinimide.

本文采用二步反应将胆固醇接枝到乙二醇壳聚糖，首先将胆固醇进行羧基化，将胆固醇与琥珀酸酐反应生成胆固醇半琥珀酸酯，然后用1-乙基-3-(3-二甲基氨丙基)碳二亚胺盐酸盐与N-羟基琥珀酰亚胺作为偶联剂，将胆固醇半琥珀酸酯的羧基与乙二醇壳聚糖主链的氨基进行反应，得到胆固醇疏水改性乙二醇壳聚糖共聚物。

The glycyrrhizic acid antigen is prepared through the process including following steps: dissolving glycyrrhizic acid in N, N-dimethyl formamide, dioxane or dimethyl sulfoxide, heliophobically adding N-hydroxy succinimide, reacting with dicyclohexylcarbodiimide at 0-10 deg.c for 2-5 hr; and reacting with carrier protein at normal temperature for 4-6 hr to obtain glycyrrhizic acid antigen.

本发明所提供的甘草酸抗体，是用甘草酸抗原免疫动物，然后从被免疫动物的血清中分离得到的；所述甘草酸抗原按如下过程制备：先将甘草酸溶解在N，N-二甲基甲酰胺、二氧六环或二甲基亚砜中，避光加入N-羟基琥珀酰亚胺，然后在0-10℃条件下与二环己基碳二亚胺反应2-5小时；接着与载体蛋白常温反应4-6小时，得到甘草酸抗原。

The cyclization of carbodiimides 2 and 6 with phenol or alcohol was studied and the results showed that the cyclization of carbodiimides 2 and 6 with phenol in the presence of solid potassium at room temperature to 40℃, the cyclization of carbodiimides 2 and 6 with alcohol should in the presence of RONa.

进一步研究了碳二亚胺2和6与酚和醇的成环反应，结果表明该碳二亚胺与酚反应在碱(固体K_2CO_3)催化条件下，室温或加热到40℃便可顺利关环，与醇反应需要用到更强的碱醇钠催化才可以顺利关环。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。