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In order to optimize technological parameters of arecoline extraction from areca nut using supercritical carbon dioxide extraction technique, the effects of extraction temperature, extraction pressure and extraction time on arecoline extraction were explored by second-order regression general rotation design.

为了优化超临界CO2萃取槟榔碱的工艺参数,通过三元二次通用旋转组合设计实施试验,考察了萃取温度、萃取压力和萃取时间因素对槟榔碱萃取量的影响。

Aim To study the absorption characteristics of berberine and its influence on glucose absorption.

目的 研究小檗碱的吸收特性和对肠道葡萄糖吸收的影响,探索小檗碱抗糖尿病作用机制。

Methods The plasma balance dialysis was used. HPLC was performed for the quantitative determination of brucine, and then the protein binding rate of brucine in rats plasma was calculated.

采用大鼠血浆平衡透析法,HPLC法测定透析袋两侧溶液中马钱子碱的质量浓度,计算马钱子碱的血浆蛋白结合率。

On the basis of all the experimental results and the molecular modelling study, it is considered that Jatrorrhizine and Berberine binds to the site I and site II mainly by hydrophobic interaction and there are hydrogen bond and electrostatic interactions.

荧光竞争实验以及分子对接研究表明药根碱和小檗碱的结合区域分别位于蛋白质的亚结构域ⅡA和亚结构域ⅢA中,主要通过疏水作用结合,但还包括静电作用力、氢键。

Alkaloid A might be gelsemine. 4 Actue toxic test of total gelsemium on mice. Its intraperitoneal LDsotmedian lethel value of total gelsemium was 7.38mg/kg(the confident limit on 95 per cent level was 6.67mg/kg ~ 7.94mg/kg).Main clinical symptoms of acute toxified mice were reducing activities, crouching, depression on low dosage (5mg/kg).

小鼠急性中毒的主要临床症状是:在低剂量(〈5mg/kg)作用下呈现活动减少、静伏、精神沉郁;在中高剂量(〉5mg╱kg)作用下呈现为呼吸困难、惊厥、阵发性痉挛甚至死亡。5、钩吻总碱的亚慢性毒性试验:生理盐水对照组和各钩吻总碱处理组1/50LD_

The results showed that K.sieversiana could grow under high salt-alkaline conditions even when the salinity reached 500mmol and pH10.51. It was proved that K.sieversiana was a halophyte species with great tolerance to salinity and alkalinity.

结果表明:碱地肤幼苗在盐度为500mmol,pH10.51的高盐高碱条件下还能生长,证明了它是既高度耐盐又高度抗碱的盐生植物。

Objective To study the hypoglycemic activity of jatrorrhizine and compare the effects of Jat, berberine, Huanglian Decoction, and compounds-mimic prescription on blood glucose level in mice.

目的研究药根碱的降血糖作用,并比较Jat、小檗碱、黄连煎剂及模拟方对小鼠血糖水平的影响。

The nitrocellulose filters are then placed on wet filter paper containing alkali, which denatures the DNA.

再将硝酸纤维素滤膜置于含碱的湿滤纸上,碱的作用是使DNA变性。

Our study results demonstrated significantly increase in ocular bioavailability of pilocarpine due to the therapy with micron emulsion.

用微乳滴眼剂后6 h,房水中仍可测出毛果芸香碱的浓度,而用滴眼液后3 h,房水中已测不出毛果芸香碱的浓度。

Objective: To determine the content of matrine in matrine suppositories.

目的:测定苦参碱栓中苦参碱的含量。

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