碘化

METHODS The target compound was synthesized from 3,4-dimethoxyphenylacetic acid via halogenation, acylation, cyclization, alkylation and iodine substitution reaction.

以3，4-二甲氧基苯乙酸为原料，经卤化、酰化、环合、烷基化、碘取代等反应制得目标化合物。

The radiochemical purity of radioiodinated 7α-O-IA-DPN is more than 95%, and still greater than 90% kept for 24 h at room temperature. Radiochemical yields is 81%～90%, and specific radioactivity is 83.25 PBq/mol.

研制结果为：碘标记的7α O IA DPN放化纯度大于95%，标记率为81%～90%，比活度高达83.25PBq/mol，室温下放置24h，放化纯度仍大于90%。

Six lateral difluorine substituted tolan -type liquid crystals were synthesized via Sonogashira cross-coupling of 4-alkylphenylacetylene and 4-iodo-2,3-difluoro-1-alkoxybenzene under the protection of argon.

用邻二氟苯为起始原料，在-78℃经过两次选择性"邻位金属化"反应、醚化反应、氧化反应制得2，3-二氟-4-碘-1-烷氧基苯，再与4-烷基苯乙炔在氩气保护下进行Sonogash ira偶联反应，制备出6种侧向二氟取代二苯乙炔类液晶。

Aniline compounds are used as raw material and reacted with anthranilic acid and then phenyl iodide as alkylating agents to give alkylating products followed by cyclizing with concentrated sulphuric acid to give a N-phenyl-acridone(or 3-ethoxyl-N-phenylacridone).The structure of intermediate and target compound are determined by IR and MS.

以苯胺类化合物为原料，先后以邻氯苯甲酸和碘苯为烷基化试剂进行了N 烷基化反应，再用浓硫酸使其环化制得N-苯基吖啶酮和3-乙氧基-N-苯基吖啶酮，并用红外光谱及质谱仪检测了各中间体及目标产物的结构。

Spiral Spirobifluorene acetylated is oxidated by m-chloroperoxybenzoic acid and hydrolyzed by sodium hydroxide ,obtaining 2,2 '- dihydroxy -9,9'- spiral Spirobifluorene .Through nitrification,Reduced by hydrazine hydrate, we may get the 2,2 '- diamino -9,9'- spiral Spirobifluorene which are characterizated by IR, 1H-NMR !

L-酒石酸和乙醇酯化得到酒石酸二乙酯，将保护羧基保护起来，然后用碘甲烷在2，3-位上两个甲基，得到2，3-二甲氧基-酒石酸二乙酯，再用氢氧化钠将其水解，得到2，3-二甲氧基-酒石酸，用五氯化磷将羧基酰化，得到2，3-二甲氧基- 1，4-丁二酰氯，经过与二环己胺反应，得到拆分配体2，3-二甲氧基–N，N，N'，N'-四环己丁二酰胺。

By the optimized condition of Sol-Gel process,the film has good quality was prepared. The performances of the electrode have been tested in the paper. The effects of solution stability,temperature and interferent have also been studied. Cyclic voltammetry was used to investigate formative process of sensitive film.

实验对溶胶和凝胶化过程中Sol储备液的配比、陈化时间、提拉速度及膜的干燥条件等因素对成膜质量的影响进行了优化；测试了Sol-Gel化学修饰碘电极的性能，并研究了待测液的稳定性、温度和共存物等因素对测定的影响。

Xinquan HuTwo new chiral backbones R-- and S--2-amino-2"-hydroxy-4,4",6,6"-tetra methyl-1,1"-biphenyl were synthesized via nitration, diazotation/iodination, Ulhnann coupling, selective reduction, diazotation/hydrolysis, hydrogenation and resolution from 2,4-dimethyl-aniline in seven steps.

以2，4-二甲基苯胺为起始原料，经过硝化反应、重氮化碘代反应、Ullmann缩合反应、选择性双硝基单还原反应、重氮化水解反应、催化氢化反应和拆分，首次合成了--2-氨基-2'-羟基-4，4'，6，6'-四甲基-1，1'-联苯和--2-氨基-2'-羟基-4，4'，6，6'-四甲基-1，1'-联苯两个对映体。

One route was that the amino-groups on the silica gel were transformed to tertiary amines by Eschweiler-clarke reaction that amine-groups react with formaldehyde and methanoic acid to prepare tertiary amines; the silica gel intermediates with tertiary amine groups reacted with chorohydrocarbons to prepare insoluble silica gel quaternary ammonium salt bactericides. Another route was that the amino-groups on the silica gel reacted with excessive chlorohexadecane; the preparing intermediates were quaternized with iodomethane to obtain insoluble silica gel quaternary ammonium salt bactericides.

一条路线是根据埃施韦勒-克拉克(Eschweiler-clarke)胺甲基化反应，进行胺基叔胺化反应，制成带有叔胺官能团的硅胶中间体，此中间体上的叔胺与卤代烷反应生成杀菌活性官能团季铵盐，制成硅胶类水不溶性季铵盐杀菌剂；另一条路线是带有胺反应活性中心的硅胶与过量正氯代十六烷反应，得到的中间体再用碘甲烷季铵化，得到最终产品——水不溶性季铵盐杀菌剂。

The famciclovir was synthesized from purine by a series of steps by Acylation, Decarboxylation, Reduction ,and so on; Derivatives of these intermediates is described from the 6-chloro- 9H- purin-2-amine as raw materials in different conditions when the iodine and bromide were synthesized with the addition of two intermediate 6-bromo-9H-purin-2-amine and 6-iodo-9H-purin-2-amine; There is elaborated from the main part of a acetophenone, urineaminohydrochloride, phenylhydrazine, ethyl acetoacetate as raw material through a series of reactions to synthetic 3-phenyl-4-formylphenyl pyrazole and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-aldehyde two pyrazole aldehyde, and then with 2-amino-6-chlorine-9-(2-methicillin-oxo-co-methyl-4-yl) purine reaction of the two new pyrazole purine Schiff bases.

本论文主是采用以鸟嘌呤为原料，经过一系列的酰基化，脱羧，还原等反应作用下最终得到了产物2-氨基-9-(4-乙酰氧基-3-乙酰氧基甲基丁基)嘌呤；其中的中间体衍生物主要是阐述从以2-氨基-6-氯鸟嘌呤为原料通过在不同的条件下进行溴代与碘代分别合成了另外两种中间体2-氨基-6-溴鸟嘌呤及2-氨基-6-碘鸟嘌呤；还有一部分主要是阐述从以苯乙酮，盐酸氨基脲，苯肼，乙酰乙酸乙酯为原料通过一系列的反应先合成3-苯基-4-醛基吡唑及5-氯-3-甲基-1-苯基-1H-吡唑-4-甲醛这两个吡唑醛，然后再与2-氨基-6-氯-9-(2-甲氧羰基丁酸甲酯-4-基)嘌呤反应得到了两个新型的吡唑嘌呤席夫碱

The results indicated that the resistant starch formed during extrusion resulted in the problems of iodine reactions of worts containing extruded rice.

提出挤压膨化时形成的抗消化淀粉，应是造成挤压膨化大米啤酒辅料糖化醪的碘反应出现问题的原因。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。