硬化组织

Concentration of 2 drugs in sclerotic bone wall were much lower than that in sub-normal bone and dissolved bone wall.

2Ⅰ组中硬化骨结核病变组织的药物浓度仅为各药的最小抑菌浓度水平，远低于亚正常骨结核病变组织和溶解骨结核病变组织。

The surface hardening of 40Cr steel was performed on a surface grinder by transverse feed grinding;the changing trends of microstructure and wear behavior of surface hardened layer were researched.

在平面磨床上采用横向进给磨削方式对40Cr钢进行表面硬化处理，研究了磨削表面硬化层组织与磨损性能的变化趋势。

The experiments show that the remelting hardening layer consists of melting zone, quenching zone and heat affected zone. From surface to internal, the respective microstructures are extremely small hidden-crystal martensite and a few residual austenites, hidden-crystal martensite and carbides and residual austerite, martensite and backfire troostite and ferrite.

实验表明：熔凝硬化层由熔化区、相变硬化区和热影响区组成；由表及里组织分别为极细隐晶马氏体＋少量残余奥氏体、隐晶马氏体＋碳化物＋残余奥氏体、马氏体+回火屈氏体+铁素体。

Research shows : laser treatment, the hardening layer from the melting zone, transformation hardening and the heat-affected zone, organizations to small uniform martensite, have a high density of dislocations, which are high hardness and wear resistance of the main reasons.

研究表明：激光处理后的硬化层由熔凝区、相变硬化区和热影响区，组织为细小均匀的马氏体，产生了高的位错密度，这些是硬度和耐磨性高的主要原因。

Cases healthy subjects served as control. In addition, density of glomerular matrix membrane and quantity of cell in glomeruli were measured with CMIAS image analysis system by computer. Global sclerosis, cellular crescents, fiber or fibrocellular crescents were measured with Memphis scope. Tubulointerstitial lesions were examined with semi-quantitative grades (including O-III grades).Results Compared to normal control, there was a significant increase of urinary TGF-betaK IL-6 and Col-lV levels in patients with IgAN (p. 01). There were also significantly positive correlation between the levels of urinary TGF-betaK Col-IV and density of glomerular matrix membrane ., interstitial fibrosisp.

采用酶联免疫吸附法测定尿TGF-β1(Transforming growth factor-β1)、尿IL-6(interleukin-6)和尿Col-Ⅳ(type Ⅳ Collagen)；采用免疫组织化学法检测肾组织TGF-β1、Col-Ⅳ表达；应用CMIAS多功能真彩色病理图像分析系统对肾小球基质基底膜面密度和细胞个数进行半定量测定；对球性硬化、节段硬化、细胞新月体及纤维或纤维细胞新月体所占肾小球百分数和肾小球IgA沉积免疫荧光强弱的判断采用Memphis法进行评分；肾小管间质病变程度采用光镜下半定量分级法(包括0-Ⅲ级)。

Theurinary IL-6 level positively correlated with density of glomerular matrix membrane, global sclerosis, fiber or fibrocellular crescents and interstitial fibrosis (p. 05). According to the degree of density of glomerular matrix membrane and interstitial fibrosis, urinary Col-IV level had better correlation than urinary TGF-betal and IL-6 levels.In IgAN, Col-IV showed increased expression in diseased renal tissue whereas the site of expression of TGF-betal was mainly localized within the cytoplasm of tubular epithelial cells. Interstial expressionwas also present but glomerular TGF-betal expression was found only in patients with heavy mesangial proliferation. There was a significant correlation between glomerular positivity for Col-IV and severity of histological damage. There was also a significant correlation between positivity for TGF-betal and Col-IV in the tubular epithelial and interstitial lesions. In contrast, there was no ralationship between glomerular positivity for TGF-betal and severity of histological damage.The urinary TGF-betal level paralleled tubular TGF-betal expression.

结果 ①IgAN患者尿TGF-β1、IL-6、Col-Ⅳ水平较健康人明显增高(P＜0.01)，该变化与血中的浓度无关(P＞0.05)；②尿TGF-β1水平与小管间质TGF-β1阳性表达呈正相关(P=0.000)，而与小球TGF-β1阳性表达无关(P＞0.05)，尿Col-Ⅳ水平与小球和小管间质Col-Ⅳ阳性表达均呈良好的相关性(P＜0.01)，还与小管间质TGF-β1阳性表达呈正相关(P＜0.05)：③小球Col-Ⅳ阳性表达与肾组织慢性病变密切相关(P＜0.05)，小管间质Col-Ⅳ和TGF-β1阳性表达均与肾小管间质病变呈良好的相关性(P＜0.01)，而小球TGF-β1阳性表达与肾组织损伤无关(P＞0.05)；④尿TGF-β1、Col-Ⅳ水平与肾小球基质基底膜面密度、小管间质病变呈正相关(P＜0.01)，与小球内细胞数呈负相关(P＜0.05)，该结果与其在组织中的表达一致；尿IL-6水平浙江大学硕士学位论文尿TGF一B一、IL一6和Col一IV在IgA肾病中的应用价值与基质基底膜面密度、球性硬化、纤维或细胞纤维新月体所占肾小球百分数及小管间质病变均有显著的相关性(F.05)；在轻度肾病理损伤时，尿'l'G卜pl、I卜6、Col一IV水平即升高，而尿Col一W在反映细胞外基质积聚和间质纤维化程度上比尿TGF一pl和IL一6有更好的相关性。

The results of the micro-structures showed that the cells of fresh and calcium-hardened carrots are isodiametrical and polyhedral and the cell walls are smooth. When heated at 110℃ and 121℃ for 10 mm, the cells of calcium-hardened carrots were still maintained. The intercellular spaces of carrots without calcium-hardening were lost when they were cooked at 121℃ for 30 min and the structure completely collapsed.

在微细构造方面：新鲜及钙硬化之胡萝卜细胞呈多角形且细胞壁平顺少有皱摺，在110℃及121℃烹煮10 min仍可维持完整细胞形状；未钙硬化之胡萝卜於121℃烹煮30min后细胞间隔消失，组织完全崩塌。

Fluvastatin not only can decrease lipid and 24-hour urinary protein excretion in adriamycin-induced nephropathic rats, but also retard chronic progressive kidney damage by increasing expression of MMP-9 in renal tissues.

结论在阿霉素肾病大鼠肾小球硬化模型中，氟伐他汀具有降血脂、减少尿蛋白的作用外，还可以通过上调MMP-9在肾组织的表达和减少ECM积聚，延缓肾小球硬化的进展。

As regards to age,gender andhistopathological characters,the 33 cases were as follows:①age,27-67years old(Median 45 years old);②gender,28 males and 5 females;③themaximum diameter of lesions,1.0-12.5cm(Mean5.9cm);④the histology,trabecular type 18 cases(18/33,54.5%),pseudoglandular 4(4/33,12.1%),compact 7(7/33,21.2%)and scirrhous 4(4/33,12.1%);⑤Edmondson-Steiner classification,gradeⅠ3 cases(3/33,9.1%),Ⅱ14(14/33,42.2%),Ⅲ 12(12/33,36.4%)and Ⅳ 4(4/33,12.1%).

年龄、性别及组织病理学方面结果如下：①年龄，27-67岁(Median 45岁)；②性别，男性28例，女性5例；③肿块最大径，1.0-12.5cm(Mean5.9cm)；④组织学类型，小梁型18例(18/33，54.5％)，假腺管型4例(4/33，12.1％)，致密型7例(7/33，21.2％)及硬化型4例(4/33，12.1％)；⑤Edmondson-Steiner分级，Ⅰ级3例(3/33，9.1％)，Ⅱ级14例(14/33，42.2％)，Ⅲ级12例(12/33，36.4％)及Ⅳ级4例(4/33，12.1％)。

Effect of tungstic electrode argon arc hardening parameters on microstructure and mechanical properties of boron cast iron surface was investigated.

采用氩弧重熔技术在硼铸铁表面进行表面硬化改性处理，研究了钨极氩弧硬化工艺参数对硼铸铁表面组织和性能的影响。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。