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硬化的细胞

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Objective To investigate the relationship of atherosclerosis and vascular cell adhesion molecule-1 (VCAM-1) gene expression.

目的 探讨动脉粥样硬化与血管细胞黏附分子-1(VCAM-1)基因表达的关系。

Objective: To study the distribution of mast cells in atherosclerotic lesions of human coronary arteries.

目的:探讨肥大细胞在冠状动脉粥样硬化斑块不同区域的分布情况。

This is a high magnification of the aortic atheroma with foam cells and cholesterol clefts.

高倍显示动脉粥样硬化时的胆固醇结晶和泡沫细胞。

Furthermore, irnmunohistochemistry technique was explored to analyze the expression of CD40 and CD40L in the human aorta atheroma.

细胞内游离钙升高在动脉粥样硬化发生、发展过程中有极其重要的作用。

Aim To explore the effect of auricularia auricula polysaccharide on the proliferation of vascular smooth muscle cells in the formation of atherosclerosis.

在动脉粥样硬化(atherosclerosis,As)发生和发展过程中,血管平滑肌细胞(smooth muscle cell,SMC)的增殖和向内膜下迁移起重要作用。

Sclerostin expression and distances of each osteocyte to the canal surface and cement line were assessed for all osteonal osteocytes in 636 unremodelled osteons chosen from fields ( approximately 0.5mm diameter) with at least one canal staining for alkaline phosphatase (ALP; a marker of bone formation).

我们评估了对636个未重塑的骨单位中所有的骨单位骨细胞的硬化蛋白表达和每个骨细胞到管道表面和粘合线的距离,这些骨单位从至少一个管道碱性磷酸酶(ALP;骨形成标志物)染色的区域选择(直径大约0.5mm)。

Therefore, CRP could mediate E-LDL participating in the early stage of atherogenesis. CRP is an ancient conserved protein whose initial role as a pattern recognition molecule may have been to defend against bacterial infections, but whose present biological role appears quite complex. CRP is protective against a variety of bacterial infections and inflammatory stimuli as an opsonin. It is likely that the activity of CRP in humans is either pro- or anti-inflammatory is dependent on the context in which it is acting.

由于CRP的识别相可以结合被暴露出磷酸胆碱结构的E-LDL,形成E-LDL/CRP复合体,而内皮细胞表面能以高亲和力识别CRP的配体相,从而CRP-相性结构具有结合E-LDL,被内皮细胞捕获,引起脂质沉积和激活补体、触发炎症反应的可能性,这样可以解释早期动脉粥样硬化为何同时存在E-LDL、CRP、补体,而这三种物质在同时、同地出现绝非一个巧合。

ConclusionsRupture or disspearence of internal elastic layer, soakage of inflammation cell, different stage of atherosclerosis, apoptosis of SMC and changes of ECM, and so on are the pathological and morphological base of the occurrence and development of ISA.

内弹力层的断裂或消失、炎性细胞浸润、动脉粥样硬化改变、中膜SMC的凋亡变薄、细胞外基质纤维的排列紊乱、减少等变化是ISA发生发展的病理形态学基础。

Objective Observe the effect of total panax notoginseng on the proliferation and cell cycle of the SD rat's mesangial cells. To investigate the possible mechanism of tPNS's inhibiting effect in prevention and cure the glomerulitis and glomerular sclerosis of the MCs. Methods Extract the MCs from heathy SD rat, culture and passage the cells.

目的:观察三七总皂苷(total Panax Notoginseng Saponins, tPNS)对体外培养的SD大鼠肾小球系膜细胞(Mesangial cells, MCs)增殖以及细胞周期的影响,以探讨tPNS在防治肾小球炎症和硬化中的作用及可能机理。

Among the earliest events in atherogenesis are the binding of monocytes to endothelium and their migration via the junctional spaces between endothelial cells till to the subendothelial spaces.

在高脂血等情况下,血液中的单核细胞不断粘附、进入动脉内膜并在内膜下聚集成为泡沫细胞是动脉粥样硬化发生发展过程中的重要环节。

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