硬化的细胞

Then test of film cell growth by high sugar, LPS, high sugar plus LPS was done with the result showing that FANG KIDNEY capsule can restrain the growth of film cell and composition of external base, it can be concluded that it has obvious effect in preventing the hardening of kidney small cell.

为进一步探讨糖肾胶囊的作用机制，还采用国内外经典细胞培养方法，成功地培养出肾小球系膜细胞，在此基础上进行高糖、LPS、及高糖加LPS诱导细胞膜增生，结果发现糖肾胶囊能抑制系膜细胞增生及细胞外基质胶原合成，证明其对防止肾小球硬化有明显作用。

Puente Navazo MD, Daviet L, Ninio E,et al. Identification on human CD36 of a domain (155-183) implicated in binding oxidized low-density lipoproteins.

动脉粥样硬化最早可见的症状是负荷脂类的巨噬细胞在血管内壁形成，这类细胞称为泡沫状细胞［25～27］。

PPARγ expression in PAN-treated rats at 12 weeks was present in podocytes and in mesangial cells in segmentally sclerotic glomeruli, with occasional parietal epithelial cell staining.

给予PAN后，PPARγ可以在节段硬化小球的足细胞和系膜细胞上表达，部分在壁层上皮细胞表达。6周后给予吡咯列酮治疗，可以减少系膜区的PPARγ染色，但足细胞上的染色明显增强，伴有小球硬化明显减轻。

Methods: Effect of SKI, a herbal preparation for lowering adverse Qi, despelling turbidness, supplementing Qi and activating circulation, and Benazepril were observed by cultured glomerular mesangial cell technique in vitro.Results: SKI could inhibit the fibronetin, laminin, and type Ⅳ collagen of ECM, and the action was dose-dependent.

肾小球硬化是多种原因引起肾小球损伤后出现的共同转归，是慢性肾功能衰竭的主要病理基矗近年来，随着对肾小球硬化机制认识的不断深入，肾小球系膜细胞、细胞外基质及各种细胞因子在肾功能进行性减退过程中所起的作用倍受关注。

Objective To study the mechanism of monocyte recruitment in atherogenesis and to clarify the effect of monocyte chemotactic protein-1 (MCP-1) in this process.

目的 了解动脉粥样硬化发病过程中单核细胞粘附并进入动脉内膜的机制，分析单核细胞趋化蛋白-1（MCP-1）基因表达对单核细胞粘附动脉内膜的作用。

It is mainly inhibited as glomerular sclerosis, renal interstitial fibrosis and intrarenal vascular sclerosis.

目前，肾保护的研究主要从防治肾小球硬化、肾间质纤维化和肾内血管硬化等方面进行，其中减少细胞外基质过度积聚是其核心环节。

Osteopetrotic osteocyte lacunae had lower alignment than osteopenic and osteoarthritic lacunae as indicated by their lower degree of anisotropy.

骨质疏松症和骨质硬化症骨细胞陷窝排列的各向异性程度较低，提示骨质硬化症的骨细胞陷窝排列整齐度较前二者为低。

These indicated that endothelial cells of the mural coronary artery are free from atherosclerosis due to higher shear stress caused by myocardial bridge. The intima of the section proximal to mural coronary artery was likely to be sclerosed due to the lower and oscillatory shear force.

提示 壁冠状动脉内皮细胞受到心肌桥压迫导致血流切变力增高产生适应性反应，对内皮细胞有保护作用，而其近段内皮细胞由于切变力较低容易被损伤，成为动脉粥样硬化发生的基础。

All patients were postmenopausal (median age 61.0 y; range, 45-76). Squamous cell hyperplasia was identified in 1 case and lichen sclerosus in 1 case. The invasive squamous cell carcinoma was of keratinizing type in 3 cases and basaloid in 1 case.

这4名患者均为绝经后女性（中位年龄61.0岁，范围：45-76岁）。1名患者确认有鳞状细胞增生，其他3名有硬化性苔藓。3名患者的浸润性鳞状细胞癌为角化型，另一名为基底细胞样。

Moreover, in order to make clear whether IV infection touches off the cause and its pathogenesis of artherosclerosis inflammatory reaction. The study also uses IV of type A1 and A3 to infect repeatedly Jimpy mice with E gene defect, to observe AS histology change of Jimpy mice aorta and detect the change of IV antibody and inflammatory reaction medium (eg.TNF-α, IL-1) in Jimpy mice serum and express of monocyte chemotactic factor( MCF-1) and nuclear factor kB in Jimpy mice aorta tissue .

另外，为了弄清流感病毒感染是否是触发动脉粥样硬化炎症反应的发生原因及其机理，本研究还用A1、A3型流感病毒反复感染载脂蛋白E基因缺陷小鼠，观察小鼠主动脉的动脉粥样硬化组织学改变，并检测小鼠血清中流感病毒抗体、炎症反应介质（如TNF-a、IL-1等）变化情况以及小鼠主动脉组织中的单核细胞趋化因子-1（MCP-1）和核转录因子kB表达情况。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。