硬化的细胞

After over expression of EL, the bionomics of endothelial cells is changed, and these changes may participate the pathophysiology of atherosclerosis.

内皮细胞高表达EL后对内皮细胞自身的生物学活性有影响，这可能与动脉粥样硬化的病理生理过程有关。

After over expression of EL, the bionomics of endothelial ce1ls is changed, and these changes may participate the pathophysiology of atherosclerosis.

内皮细胞高表达EL后对内皮细胞自身的生物学活性有影响，这可能与动脉粥样硬化的病理生理过程有关。

Contain HA,pawpaw extract,whitening and moisturizing factor,quickly penetrate into deep skin,soften dear and hard hominess,dissolve dirt from hair follicle,instantly float and seperate impurity and harmful substances,remove dirt after massage,combine nourishing essence,moisture and regenerate epidermic cells,strengthen skin moisture and firmness,inhibit hominess sclerosis as the activating and whitening product with instant effect after use

本品含透明质酸，木瓜精华液，美白保湿因子等，能即时渗透肌肤深层，松软死皮及硬化的角质，溶解毛囊中的诸塞物，令各种杂质和有害物浮现被分离，经过轻柔按摩，即时被清除肌肤外，滋养成分更滋润新生的表皮细胞，增加肌肤的柔嫩度和弹性，减少角质硬化，使立即见效的醒肤美白品

Furthermore, high fat diet induced hyperlipidemia and fatty liver disease are also related to atherosclerosis. The pigments of Opuntia dillenii fruit was found to possess antioxidative activity.

而低密度脂蛋白的氧化修饰以及巨噬细胞所受到的脂质过氧化作用皆在动脉粥状硬化的过程中扮演了重要的角色，另外由高脂质饮食所导致的高血脂症以及脂肪肝现象也被认为和动脉粥状硬化的形成有关。

Domenstic and abroad academicians have disclosed the influence mechanism of these factors from different aspects, including the gene polymorphism and gene mutation in genetics, which are a susceptible factor for cardiovascular complication in type 2 diabetes patients; the dysfunction of endotheliocyte, the metabolic disorder of lipid, and dysfunction of vascular smooth muscle, which can lead to the formation of arteriosclerosis;the formation of immune complex,which can also accelerate the destruction of artery paries;the sctivation of protein kinase C and the dysfunction of platelet, which may ultimately result in the formation of thrombus and influence the function of cadiac muscle cells.

其中主要包括：遗传学方面的基因多态性和基因突变，二者均是2型糖尿病合并心血管疾病的一个易感因素，内皮细胞功能障碍、脂质代谢异常及血管平滑肌细胞功能异常均可导致动脉粥样硬化的形成；免疫复合物的形成可加速动脉壁的破坏；蛋白激酶C的激活及血小板功能受损最终导致血栓形成并影响心肌细胞的功能。

1.To study the expression of in the different glucose concentration with the time changing. 2.To study the effect of different concentration of Hepatocyte Growth Factor on the Integrin-linked kinase in protein and mRNA level by Mesangial Cells in high concentration (25 mmol/L) of glucose. 3.To study the effect of different concentration of HGF on the Fibronectin'secretary by Mesangial Cells. 4.To study latent therapeutic action and possible mechanism of HGF on the glomeruler sclerosis. The difference of ILK's experession on mRNA level in different concentration of glucose and HGF are detected by means of revers transcription-polymerase chain reaction,and by means of immunohistochemistry to detect their difference in protein level;the effection of HGF to the FN's secretary in high glucose are detected by means of enzyme linked innunosorbent assay.

1探讨在不同的血糖浓度下大鼠肾小球系膜细胞中ILK伴随时间变化在蛋白和mRNA水平表达的差异 2探讨不同浓度的HGF对高糖环境下(25mmol/L)大鼠肾小球系膜细胞中ILK在蛋白和mRNA水平表达的影响 3探讨不同浓度的HGF对高糖环境下大鼠肾小球系膜细胞的FN的分泌的影响 4初步探讨HGF对肾小球硬化的潜在的治疗作用及其可能机制采用RT-PCR的方法分析在不同血糖浓度和不同HGF浓度下大鼠肾小球系膜细胞中ILK在mRNA水平表达的差异；采用免疫组织化学的方法直观的观察它们在蛋白水平表达的差异；采用ELISA法分析不同浓度的HGF对高糖环境下大鼠肾小球系膜细胞的FN的分泌的影响。

Cholesterol contributes to the generation and development of atherosclerosis while non sterol isoprenoids play a role in regulation of cell proliferation, signal transduction and ge...

胆固醇在动脉粥样硬化的发生、发展中起重要作用，而异戊二烯则参与细胞增殖调节、信号转导及肿瘤发生过程。目前，该酶已成为一些有效的抗动脉粥样硬化药物治疗的靶点。

The reason Manshen NO.1 prescription can restrain accrementition in intercapillary cells and mesangial region may be due to its adjustment of NO and ET-1's contents in vivo. It is worth of doing further researchs in the future.

1、慢肾1号方对系膜增生性肾炎有良好的治疗作用，改善症状，抑制系膜细胞及基质区的增生，从而阻止肾小管硬化的发展，防止肾功能衰竭的发生，2、肾慢1号方能够提高模型组小鼠血清NO的含量，降低ET-1的含量，使之恢复正常。3、慢肾1号方可能是通过调节体内细胞因子(NO及ET-1)的含量，从而达到抑制系膜细胞及基质增生的目的，值得深入研究。

The hypercholesterolemic rats were selected to imitate early stage of human atherosclerosis The effects and mechanism of n-3 PUFA on endothelium were investigated with the following parameters: the morphological appearance and arrangement of endothelium stained by Ag, in vitro endothelium-dependentrelaxation of aortic ring, endothelial permeability test using Even′s Blue, blood lipid and body weight in one-week intervals, excitative and emissive spectrum of RBC membrane labeled by DPH (1, 6-Diphenyl-1, 3, 5-hexatriene), fluidity of RBC membrane, plasma and RBC membrane LPO

在整体和离体水平，选用大鼠高脂血症模型模拟动脉粥样硬化早期状况。用114只大鼠多指标着重研究n-3多不饱和脂肪酸在高脂血症状态下对内皮的保护作用，以探讨其预防动脉粥样硬化的机理。所采用指标包括：浸银法观察内皮细胞排列与形态；离体血管环观察内皮依赖性舒张；伊文氏蓝染料法观察内皮通透性。为探讨作用机理，进行了血脂和体重的动态监测、DPH(1，6-二苯基-1，3，5，乙三烯)标记红细胞膜的荧光光谱测定、红细胞膜流动性测定、血浆和红细胞膜脂质过氧化物测定。

There were significant differences between all the experimental groups and the control group (F=193.25, P＜0.01). Conclusions IL-1β and TNF-α induce a strong expression of MCP-1 mRNA and protein in HUVECs. Both cytokines may be involved in the atherogenesis by inducing the liberation of MCP-1 by endothelial cells and increasing the recruitment of monocytes into the subendothelial space.

IL-1β和TNFα均能显著增强内皮细胞MCP-1 mRNA和蛋白的表达，提示它们通过诱导内皮细胞产生MCP-1，吸引单核细胞迁入动脉内膜而参与动脉粥样硬化的发生和发展。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。