硬化的细胞

Objective: To investigate the effect of resveratrol on Chemotactic Factors of Monocyte,the Plaque Stabilization of atheromatosis and the effect of antioxidation and the relationship with CD40 Pathway. And to probe the molecular mechanism for resveratrol of action on anti-atherosclerosis .

目的：研究白藜芦醇对单核细胞趋化相关分子的影响、抗氧化、稳定粥样斑块的作用及其与CD40途径的关系，探讨白藜芦醇抗动脉粥样硬化分子作用机制。

More recently, it has become clear that endothelial desquamation is not common and that an intact endothelial cell layer covers developing atherosclerotic lesions.

最近，可以确定的是内皮剥落并不常见，而且，完整的内皮细胞层会覆盖住正在形成的动脉粥样硬化病灶。

The predecessors have studied a lot to the pharmaco-analysis of the puerarin from clinical.They found that the puerarin is a effective medicine for the endeictic of high blood pressure,hyperlipemia,coronary artery disease,angina cordis,cerebral thrombosis,and at the same time,the therapeutic efficacy of puerarin is very effective to preserve the arterial blood vessel endothelial,to treat the disease of artherosclerosis,to prevent the thrombogenesis.

前人多从临床的角度对葛根素进行过药理分析，发现葛根素对于高血压、高血脂、冠心病、心绞痛、脑血栓等症状的治疗效果突出，对保护动脉血管内皮细胞、阻止动脉粥样硬化，防止血栓形成的作用也十分明显。

Objective To observe the Influence of valsartan on the expression of monocyte chemoattractant protein-1(MCP-1) in nephridial tissue of glomerular sclerosis rats,and to study the protection of angiotensin-converting enzyme Ⅱtype-1 receptor antagonist(AT1RA) on kidney.

目的观察缬沙坦对肾小球硬化大鼠肾组织单核细胞趋化蛋白-1(MCP-1)表达的影响，探讨血管紧张素转化酶Ⅱl-型受体拮抗剂(AT1RA)对肾脏的保护作用。

Results Alter 12 weeks of experiment, as compared with the control, the pathologic lesions in aortas were much less severe in the treated group, with the expression of VCAM-1 protein in aortas significantly reduced.

结果 12周末，与去势对照组比较，雌激素可显著减轻主动脉的动脉粥样硬化病理损害，抑制主动脉血管细胞黏附分子－1的蛋白表达。

Objective To investigate the expression of sialic acid-binding immunoglobulin-like lectin-1 (Siglec-1) on peripheral blood lymphocytes, monocytes and neutrophils in patients with coronary heart disease and explore the role of Siglec-1 in coronary atherogenesis.

目的 观察唾液酸黏附素(Siglec-1)在冠心病患者外周血淋巴细胞、单核细胞和中性粒细胞上的表达水平，并探讨其在冠状动脉粥样硬化发病过程中的作用。

Objective To establish a vascular smooth muscle cell model of rat in vitro.

目的 建立大鼠主动脉平滑肌细胞体外培养模型，为动脉粥样硬化等心血管疾病的发病机制的研究提供了重要手段。

Objective: Different subsets of T lymphocytes have different functions in atherosclerosis advancement.

目的：不同的T细胞亚群在动脉粥样硬化进展过程中起不同的作用。

Methods The changes of contents of AGEs in plasma and the abdominal aorta and changes of VSMC of the abdominal aorta were investigated with methods of fluorospectrophotometry, immunohistochemistry, computer image analysis and transmission electron microscopy on streptozotocin-induced diabetic rats. Results From the fourth week, in diabetic rats, the contents of AGEs in plasma and the abdominal aorta increased, the relative area of α-SM-actin in the abdominal aorta decreased, the density of nucleus of VSMC increased, and mitochondria and rough endoplasmic reticules in VSMC increased.

后者在早期主要是血管平滑肌细胞(vascular smooth muscle cell， VSMC)和胶原纤维增多，弹性纤维减少，动脉增厚等，引起动脉的顺应性降低，舒张功能减弱［1～3］；晚期主要表现为动脉粥样硬化和动脉硬化，其中以VSMC的增生和迁移较为突出，其表型也由收缩型转化为合成型［4，5］。

Results: All lesions showed classical features on CT with varying degree of matrix mineralisation, 8 of 10 located at attached bone of vertebral b...

结果：全部10例骨母细胞瘤病灶内部CT表现均为典型的斑点状或沙粒状骨化，10例中有8例位于附件骨，7例表现有周围不连续的硬化带，3例受累骨密度普遍增高，2例出现附近软组织肿胀影。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。