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硬化

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Objective: To investigate the relationship between blood lipid,apolipoprotein and carotid atherosclerosis in type 2 diabetes mellitus.

目的:探讨2型糖尿病颈动脉粥样硬化与血脂及载脂蛋白的关系。

Objective:To investigate the relationship between hyperglycemia and carotid atherosclerosis in Tibetan population.

目的:探讨藏族人群高血糖症与颈动脉粥样硬化的关系。

Results: In the 23 cases of disease group, 16 cases were unilateral and 7 cases were bilateral. X-ray examination showed local prominence between ischium and pubis in all cases. Lamellar changes of the bone inhomogeneous in density with round translucence were found in 8 cases accompanied with intact cortex. Mild osseous hyperplasia was found in 8 cases without changes of periosteum and soft tissues. CT examination of 8 cases presented with local prominence between iscbium and pubis, translucence, cataclasm, discontiguous osteal cortex with irregular ends, sclerotic medullary cavity of honey surroundings, but no sequestration and changes of periosteum and soft tissues. The above-mentiooed X-ray features appeared in 14 cases among normal group, bilateral in 3 cases.

结果:病变组23例中,16例为单侧,7例为双侧。X线表现为坐骨耻骨结合处局限性骨膨隆,8例有层状改变,病变区内密度不均,有类圆形低密度透光影,骨皮质完整,8例周围骨质轻度增生,未见骨膜反应和软组织改变。8例CT表现为坐骨耻骨结合处局部膨大,其内有低密度透光区,有碎裂,骨皮质连续性中断,断端边缘欠整齐,邻近的髓腔轻度硬化,无明显的死骨和骨膜反应,邻近的软组织正常;正常组中14例出现上述X线改变,其中3例为双侧性。

Mondini dysplasia may occur in association with anomalies in other organs. A 26-month-old boy died of congenital heart disease. His temporal bone was harvested within 15 hours after death, processed and embedded in celloidin.

本科报告病例为26个月的小男孩,是因先天性心脏病去世,经死后15小时尸体解剖,且取出颞骨,经固定、脱钙、中和、脱水、赛璐锭包埋、硬化后,以20μ的厚度,水平方位连续切片。

Methods Monocytes were isolated from peripheral blood of coronary heart disease cases by FicollHypaque density gradient centrifugation.

目的 建立人单核源性泡沫细胞的疾病模型,为动脉粥样硬化的发生发展机制及其防治研究提供新途径。

Antigangliosides GM1 antibody and cephalin antibody in serum (n=28) and cerebrospinal fluid (n=18) were examind in MS patients with ELISA assay.

采用ELISA方法测定多发性硬化患者活动期血清(28例)和脑脊液(18例)的GM1抗体、脑磷脂抗体和髓鞘碱性蛋白。

Results We found GM1 antibody in 36% and cephalin antibody in 43% of MS patients in serum,GM1 antibody in 11% and cephalin antibody 18% in cerebrospinal fluid.The levels of antibody in serum of treated_MS patients were significantly lower than those in active MS patients.The levels of myelin basic protein in serum and cerebrospinal fluid in MS were significantly higher than those in control group.

结果 多发性硬化患者血清GM1抗体阳性率 36%,脑磷脂抗体为43%;脑脊液GM1抗体为11%,脑磷脂抗体为18%,与对照组比较差异均有显著性;血清和脑脊液的髓鞘碱性蛋白增高亦有意义。

Results We found GM1 antibody in 36%and cephalin antibody in 43%of MS patients in serum,GM1 antibody in 11%and cephalin antibody 18%in cerebrospinal fluid.The levels of antibody in serum of treated_MS patients were significantly lower than those in active MS patients.

结果 多发性硬化患者血清GM1抗体阳性率为36%,脑磷脂抗体为43%;脑脊液GM1抗体为11%,脑磷脂抗体为18%,与对照组比较差异均有显著性;血清和脑脊液的髓鞘碱性蛋白增高亦有意义。

To perform large-scale multiplex analysis of antibody responses to lipids in multiple sclerosis, we developed microarrays composed of lipids present in the myelin sheath, including ganglioside, sulfatide, cerebroside, sphingomyelin and total brain lipid fractions.

我们采用微列阵技术对多发性硬化脂质反应性抗体进行大规模多重分析,微列阵组成包括髓鞘中的脂质,其中包括神经节苷脂、脑硫脂、脑苷脂、鞘磷脂、总的脑脂质。

Objective To investigate the molecular mechanism and marker proteins of multiple sclerosis in human cerebrospinal fluid.

目的 探讨多发性硬化发病的分子机制并寻找其脑脊液蛋白质标志物。

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