硫醇

The present invention relates to a process for rapid solution synthesis of a peptide, the process comprising repetitive cycles of steps-: a coupling step, using an excess of an activated carboxylic component to acylate an amino component, a quenching step in which a scavenger is used to remove residual activated carboxylic functions, wherein the scavenger may also be used for deprotection of the growing peptide, one or more aqueous extractions and optionally, a separate deprotection step, followed by one or more aqueous extractions, characterised in that the process comprises at least one step, referred to as step, in which an amine or a thiol comprising a free anion or a latent anion is used as a scavenger of residual activated carboxylic functions.

本发明涉及快速溶液合成肽的方法，该方法包括步骤-的重复循环：偶联步骤，使用过量的活化羧基成分酰化氨基成分，淬灭步骤，在该步骤中使用清除剂除去残余的活化羧基官能团，其中该清除剂还可以用于使生长中的肽去保护，一或多个水抽提和任选地，独立的去保护步骤，之后进行一或多次水抽提，其特征在于该方法包括至少一个步骤，称作步骤，在该步骤中包含自由阴离子或潜阴离子的胺或硫醇用作残余活化羧基官能团的清除剂。

Then Doripenem came into the market in the July ,2005. We studied the synthesis of Doripemen.Firstly, we synthesized the chemical 2 from the starting material------o-hydroxylphenylacylamine through Reformastky reaction, alkylation, Diekmann reaction, enolization, esterification and etc. Secondly, we synthesized the chemical 3 from L — hydroxylproline through the protection of carboxyl, amidogen and hydroxyl group, reduction by NaBr, SN_2 substitution and Mitsumobu reaction.

我们以水杨酰胺为起始原料，经Reformatsky反应、烷基化、Diekmann环合、烯醇化、酯化等反应合成双环母核2；再从L-羟基脯氨酸出发，经酯化保护羧基、保护氨基、保护羟基、硼氢化还原酯得醇、Sn2取代和Mitsumobu反应等合成巯基侧链3；最后由化合物3经脱保护、水解得硫醇，和化合物2在二异丙基乙基胺的作用下缩合，最后Pd／C催化脱保护，历经16步反应最终得到产物多尼培南。

Research on techniques for the synthesis of ACR impact modifier with core-shell structure;2. Preparation of polymer-tungsten-silica composite microspheres with multi-layer core-shell structures;3. Organosilicon-acrylate micro emulsion with core-shell structure was synthesized with OP-10,JFC and amyl alcohol nonionic compounded emulsifier by means of seeded emulsion polymerization.

运用种子乳液聚合工艺以OP-10/JFC/戊醇非离子复合乳化剂合成了具有核-壳结构的有机硅-丙烯酸酯微乳液，研究了复合乳化剂类型、丙烯酸酯单体、有机硅单体加入方式和含量、pH值、硫醇对微乳液聚合过程中稳定性和光泽度的影响，通过差示扫描量热仪和透射电镜对微乳液的结构进行了表征。

Organosilicon-acrylate micro emulsion with core-shell structure was synthesized with OP-10,JFC and amyl alcohol nonionic compounded emulsifier by means of seeded emulsion polymerization.

运用种子乳液聚合工艺以OP-10/JFC/戊醇非离子复合乳化剂合成了具有核-壳结构的有机硅-丙烯酸酯微乳液，研究了复合乳化剂类型、丙烯酸酯单体、有机硅单体加入方式和含量、pH值、硫醇对微乳液聚合过程中稳定性和光泽度的影响，通过差示扫描量热仪和透射电镜对微乳液的结构进行了表征。

The hybrid density functional theory is used to study formation of the junction of alkanemonothiol molecules with different terminal groups. The relationship between geometric structures of the molecular junction and the external force is obtained.

利用杂化密度泛函理论，研究了以甲基、醇基、羧基为末端基团的烷烃硫醇分子与金电极形成分子结的过程，得到了分子结的几何结构与外加压力的关系。

It has been demonstrated that the methods are successfully used for QSRR studies of quinazoline derivatives, alkypyridine, haloid alkane, ketone, alcohol, sulfur alcohol compounds.

本文成功地用该方法对喹唑啉类、烷基吡啶化合物、卤代烃、醇、羰基化合物和硫醇化合物的结构保留关系进行了探讨。

This paper describes a removal process for ethanethiol in a packed bed of the immobilized activated sludge pellets.

采用改进聚乙烯醇法制成的固定化活性污泥颗粒填充生物滴滤池，考察在不同的进气流量和进气浓度时，生物滴滤塔对乙硫醇恶臭气体的净化效率、抗冲击负荷能力以及连续运行稳定性。

The polymer particles were prepared by copolymerization of phthalic aldehyde, allyl mercaptan and ethylene glycol dimethacrylate after heating. The fluorescence intensity of the polymer particles was very weak.

利用邻苯二甲醛与烯丙基硫醇、乙二醇二甲基丙烯酸酯在偶氮二异丁腈引发下热聚合制得了一种新型聚合物颗粒。

In the second part, we studied the reactions of tonghaosu analogs with mercaptans alcohols and organic metallic reagent under acid condition. Moreover, we synthesized and determined a natural compound by using this kind of reaction.

第二部分研究了茼蒿素类似物在酸性条件下与硫醇、醇、有机金属试剂发生亲核取代反应，同时通过这类反应合成了一天然产物。

In this experimental study firstly a sulphur-bearing alkanethiol-derivatised gold nanoparticles has been selected and prepared. The alkanethiol-derivatised gold was put in the mud-stone samples bearing terreau. In varies elevated temperature the gas products were collected by foam plastics in a special installation. The measurements on the contents of gold in foam plastics and on the composition of gas phase were carried out and the comparisons for various samples were made.

本项研究选取并制备了作者认为有地质意义的含硫的金的金属有机化合物-烷基硫醇衍生纳米金，将其添加至含有机物质的泥岩样品中，在专门设计的真空装置中用泡塑收集不同温度气相产物，分析所产生气相组成及带出金的含量并与添加氯金酸水溶液的样品进行对比。

They weren't aggressive, but I yelled and threw a rock in their direction to get them off the trail and away from me, just in case.

他们没有侵略性，但我大喊，并在他们的方向扔石头让他们过的线索，远离我，以防万一。

In slot 2 in your bag put wrapping paper, quantity does not matter in this case.

在你的书包里槽2把包装纸、数量无关紧要。