硫酰胺

Firstly, 3-ethylthiobutanal was prepared from crotonaldehyde reacting with ethanehiol in triethylamine with high yield. Secondly, methyl acetoacetate was converted to 6-ethylthiohept-3-en-2-one by three steps via hydrolysis, condensation with 3-ethyltio-butanal and dehydration, then 6-ethylthiohept-3-en-2-one was cycloco ndensed with dimethyl malonate by Michael addition and Claisen condensation, followed by saponification and decarboxylation to give the intermediate of 5-(2-ethylthiopropyl)-cyclohexane-1,3-dione.

首先，以巴豆醛与乙硫醇为原料，在三乙胺的催化作用下高收率制得3-乙硫基丁醛；然后从乙酰乙酸甲酯出发，通过碱水解、与3-乙硫基丁醛缩合、脱水三步反应合成6-乙硫基-3-烯-2-庚酮，接着6-乙硫基-3-烯-2-庚酮与丙二酸二甲酯通过Michael加成和Claisen缩合成环，再通过皂化和脱羧反应生成中间体5-[2-丙基]-1，3-环己二酮；再与丙酸酐反应丙酰化，最后与0-3-氯-2-丙烯基羟胺肟化，得到目标化合物烯草酮。

All of the tripodal schiff base ligands and their complexes were characterized.

以三乙醇胺、巯基苯胺、巯基乙胺为初始原料，设计合成了六个三脚架结构的化合物，其合成路线如下：三乙醇胺与氯化亚砜反应得到三(2-氯乙基)胺(1)，然后与巯基苯胺或巯基乙胺在碱性条件下反应生成三脚架结构的三{[2-(2-氨基苯基)硫代]乙基}胺(2)或三{[2-(2-氨基乙基)硫代]乙基}胺(3)，然后再与水杨醛、2-甲酰基-8-羟基喹啉(8)、2-甲酰基-8-苄氧基喹啉(7)反应得到六种新型的含硫西佛碱化合

ES cells were maintained on gelatin-coated dishes in Iscove's modified Dulbecco medium containing 0.1 mmol/L of nonessential amino acids, 2 mmol/L of L-glutamine, 0.1 mmol/L of monothioglycerol, 15% fetal bovine serum, and 1000 U/mL leukemia inhibitory factor. Embryonic bodies were firstly formed by ES cells with hang drip method in IMDM without LIF. Six-day-old EBs were trypsinized and the cells were resuspended at a concentration of （3-4）×109 L-1 cells per 1 mL of a 1:1 mixture of culture medium and Matrigel?

实验方法：将鼠胚胎干细胞株接种于被覆明胶的培养瓶内，加入含0.1 mmol/L非必需氨基酸、2 mmol/L L-谷酰胺、0.1 mmol/L二羟基丙硫醇、15%胎牛血清、1 000 U/mL白血病抑制因子的IMDM培养液。3 d后采用&悬滴法&使细胞在不含白血病抑制因子的上述IMDM培养液中形成胚胎体，6 d后胰酶消化得到胚胎干细胞，浓度调整为（3~4）×109 L-1，与Matrigel？

Objective To determine the clinical effect of thiopental with the mechanical respiration on the heavily poisoned patients by fluoroacetamide and vccuronium.

目的探讨硫喷妥钠配合机械通气治疗重度毒鼠强和氟乙酰胺中毒的临床疗效。

Since tests prescribed in monographs have been developed using thioacetamide reagent R, if sodium sulphide solution R1 is used instead, it is necessary to include also for methods A and B a monitor solution, prepared from the quantity of the substance to be examined prescribed for the test, to which has been added the volume of lead standard solution prescribed for preparation of the reference solution.

由于专论中的试验描述使用硫代乙酰胺试液，如果用硫化钠溶液R1(0.1ml)代替，方法A和方法B的控制溶液应按照试验中待测供试品要求的数量加入到方法规定体积的标准铅对照溶液中。

Since tests prescribed in monographs have been developed using thioacetamide reagent R, if sodium sulphide solution R1 is used instead, it is necessary to include also for methods A and B a monitor solution, prepared from the quantity of the substance to be examined prescribed for the test, to which has been added the volume of lead standard solution prescribed for preparation of the reference solution.

各论中规定使用硫代乙酰胺试液，因此若要改用硫化钠溶液，无论是方法A还是方法B都应制备控制溶液。控制溶液的制法：取规定量的供试品，加入制备对照溶液所需的铅标准溶液。monograph可以翻译成&各论&，即具体品种的药典标准。

The methods described below require the use of thioacetamide reagent R. As an alternative, sodium sulphide solution R1 (0.1 ml) is usually suitable.

下面方法中所用到的硫代乙酰胺试液，通常也可以用硫化钠溶液R1(0.1ml)代替。

Objection:To investigate the significance of contrast-enhanced ultrasound in quantitative diagnosis of liver cirrhosis. Methods:Rabbits models with liver cirrhosis of different stages were successfully made by feeding them with thioacetamide solution. And a self-comparison method was adopted in the trial. The hepatic artery to vein transit time was taken as the parameter for evaluation.

30只实验兔以1.20 g／L的硫代乙酰胺水溶液作为惟一饮用水的方法建立不同阶段的肝硬化模型，应用Bracco公司生产的声诺维作为造影剂，并用自身前后对照的方法，在肝硬化模型建立前后测量肝静脉内造影剂出现的时间及肝动脉内造影剂出现的时间，两者相减得到肝动静脉渡越时间，比较肝硬化前后数值间的差异。

AIM To observe the formation and effects of nitric oxide and free radicals on acute liver injury induced by thioacetamide.

目的 用硫代乙酰胺诱发大鼠急性肝损伤，观察肝损伤过程中一氧化氮与自由基的变化。

On the basis of the above N-vinylaiton of amides,the Cu-catalyzed intramolecular C-S coupling of thiols was implemented for the first time with CuI (10 mol%) as the catalyst and K_3PO_4·3H_2O2 equiv.

在酰胺氮烯基化研究的基础上，我们进而开展了烷基硫醇分子内烯基化反应研究。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。