硫酰胺

It is especially suitable to deal with the complicated nonlinear problem-complex structure and property relations. In this paper it is applied to solve the fungicidal activity of aseries...

用该法处理硫代磷酰胺酯类衍生物杀菌作用的构效关系，并与逐步回归和偏最小二乘法作比较，模型的复相关系数R和剩余标准差Sy都较好。

Effect of Common Goldenrod Herb on rats Gastrelcosis Caused by Indocin;2. Animal Model of Helicobacter pylori Infection in BALB/c Mice with Gastrelcosis ;3. AIM To study the synthesis of zinc chlorin e 4 (1), its experimental antigastrelcosis activity as well as the protection against acute liver injuries.

蚕沙叶绿素粗品经酸碱降解反应制得二氢卟吩e6(3)，3经吡啶回流降解制得二氢卟吩e4 (2 )，2与醋酸锌络合制得 1；并测定 1对消炎痛诱发的大鼠胃溃疡的保护作用及对硫代乙酰胺、四氯化碳所致小鼠急性肝损伤的防治作用。

Objective:To observe the effect of Jiawei Zhenwu Tang on rat model of hepatorenal syndrome.

目的：研究加味真武汤对硫代乙酰胺所致肝肾综合征模型大鼠肝肾功能的影响。

Methods: The rats were injected with thioacetamide 600mg/kg twice at same time for two days to induce the model of acute hepatic failure rat except the normal group injected with the normal saline hypodermically.

按600mg/kg的剂量经皮下注射硫代乙酰胺1次，24小时后按相同剂量重复注射1次，造成大鼠急性肝衰竭模型，于实验前3天至实验结束分别给予各组大鼠生理盐水，不同剂量丹黄方及促肝细胞生长素，观察造模后48小时内大鼠病死率，并于造模48小时后经腹主动脉采血测定ALT、AST、TBil、TNF-α、IL-6，取肝组织作病检。

Results Eleven compounds were obtained and identified as sarcodonin A, scabronine B, 3β-hydroxy-5α, 8a-epidioxyergosta-6, 22-dien,(22E, 24R)-ergosta-7, 22-diene-3β, 5α, 6β-triol,(22E, 24R)-ergosta-7, 22-diene-3β-ol, benzoic acid, 4-hydroxylben-zaldehyde, 4-monopropanoylbenzenediol, ethy1-β-D-glucopyranoside, thioacetic anhydride,(2S, 2'R, 3S, 4R)-2-(2-hydroxyoctadecanoylamino) docosane-1, 3, 4-triol.

结果共分离鉴定了11个化合物，分别是：sarcodonin A、scabronine B、3β羟－5α，5α-过氧麦角甾－6，22-二烯－3β-醇、(22E，24R)-麦角甾－7，22-二烯－3β，5α，6β三醇、(22E，24R)-麦角甾－7，22-二烯－3β-醇、苯甲酸、对羟基苯甲醛、对羟基苯甲酸乙酯、乙基－β-D-吡喃葡萄糖苷、硫代乙酸酐、（25，2'R，3S，4R）-2-（2-羟基－十八碳酰胺）二十二碳烷－l，3，4-三醇。

Thioamide was refluxed with sodium hypophosphite and ppt-Ni prepared beforehand from NiCl〓·6H〓O and Zn powder in a mixture of dioxane and water to give amines in 60-98% yields (12 examples).

催化剂Ni-Zn是用氯化镍和锌粉反应制成，为合金型固体粉末，次磷酸钠作为氢供体，对12种硫代酰胺进行脱硫还原，收率60-98%。

The structural assignment of Ⅱwas supported by spectral data and was confirmed by the identification of the compound as the product obtained by synthesis from triethyl orthoacetate and 2- cyanot hioacetamide.

结构的指定得到由光谱数据的支持，确认结构是通过原乙酸三乙酯和2-氰基-硫代乙酰胺合成得到的化合物。

Results:It is suggested that the drug significantly protectes liver from CCl4,thioacetamide and galactosamine in mice and rats,lowers the activity of enzyme ALT in serum,shorten the sleep duration of CCl4-damaged mice induced by embuter,inhibites HBsAg in vitro,and potentiates non-specific immunity in mice and rats.

结果：研究表明，该药对四氯化碳、硫代乙酰胺和氨基半乳糖引起小鼠及大鼠的急性肝损伤有明显的保护作用，能降低谷丙转氨酶；缩短CCl4肝损伤小鼠戊巴比妥钠的睡眠时间；抑制体外乙肝病毒表面抗原；对非特异性免疫有一定增强作用。

Keratin mutation predisposes to mouse liver fibrosis and unmasks differential effects of the carbon tetrachloride and thioacetamide models.

角蛋白突变诱发小鼠肝脏纤维化，揭示四氯化碳和硫代乙酰胺模型的的差别效应

RESULTS: At 12 weeks after infusing thioacetamide, pathological section showed that hepatic lobules were destroyed; hepatic cord was disordered; liver cells had adipose degeneration, with few necrotic cells; interstitial fibrous tissues were hyperplastic, and folioles in some fibrous tissues, inflammatory cell infiltration were detected. These were the symptom of hepatic fibrosis.

结果：注射硫代乙酰胺12周时，病理切片显示肝小叶结构破坏，肝索排列紊乱，肝细胞脂肪变性，有少许坏死，间质纤维组织增生，有部分伸入小叶，有炎性细胞浸润，为肝纤维化症状。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。