硫酮

Firstly, 3-ethylthiobutanal was prepared from crotonaldehyde reacting with ethanehiol in triethylamine with high yield. Secondly, methyl acetoacetate was converted to 6-ethylthiohept-3-en-2-one by three steps via hydrolysis, condensation with 3-ethyltio-butanal and dehydration, then 6-ethylthiohept-3-en-2-one was cycloco ndensed with dimethyl malonate by Michael addition and Claisen condensation, followed by saponification and decarboxylation to give the intermediate of 5-(2-ethylthiopropyl)-cyclohexane-1,3-dione.

首先，以巴豆醛与乙硫醇为原料，在三乙胺的催化作用下高收率制得3-乙硫基丁醛；然后从乙酰乙酸甲酯出发，通过碱水解、与3-乙硫基丁醛缩合、脱水三步反应合成6-乙硫基-3-烯-2-庚酮，接着6-乙硫基-3-烯-2-庚酮与丙二酸二甲酯通过Michael加成和Claisen缩合成环，再通过皂化和脱羧反应生成中间体5-[2-丙基]-1，3-环己二酮；再与丙酸酐反应丙酰化，最后与0-3-氯-2-丙烯基羟胺肟化，得到目标化合物烯草酮。

Synthesis of organic sulfuric compounds in aqueous media is carried out by: using thio-olefin compounds with carbonyl compounds, acetal/keltone, hydrazone, oxime, osazone and enamine to synthesize mercaptal/keltone compounds in aqueous media; using thio-olefin compounds with alpha-hydroxyaldehyde/keltone or alpha-halogenated aldehyde/keltone to synthesize thia-olefin derivatives in a queous media; using thio-olefin compounds with alpha, beta-unsaturated hydroxy compounds, C-C treble bond, C-N treble bond, C-C double bond, N-N double bond, C-N double bond, C-S double bond, epoxy and its derivatives, aziridine and its derivatives, cyclopropane and its derivatives and halogenated carboxy to synthesize sulfoether compounds in a queous media.

含水介质中有机硫化合物的合成方法，本发明属于有机合成方法，用硫缩烯酮类化合物与羰基化合物、缩醛/酮、腙、肟、脎、烯胺在含水介质中合成缩硫醛/酮化合物，与α-羟基醛/酮或α-卤代醛/酮在含水介质中合成噻烯类衍生物，与α，β-不饱和羰基化合物、碳碳叁键、碳氮叁键、碳碳双键、氮氮双键、碳氮双键、碳硫双键、环氧乙烷及其衍生物、氮杂环丙烷及其衍生物、环丙烷及其衍生物、卤代烃等在含水介质，中合成硫醚化合物。

In the first part, five new 4-acyl pyrazolone 4-ethyl-thiosemicarbazones compounds: 1-Phenyl-3-methyl-4-(4-bromo)benzal-pyrazol-5-one N(4)-ethyl-thiosemicarbazone (PM4Br BP-ETSC), 1-Phenyl-3-methyl-4-(4-methyl)benzal-pyrazol-5-one N(4)-ethyl-thiosemicarbaz -one (PM4MBP-ETSC), 1-Phenyl-3-methyl-4-benzal-pyrazol-5-one N(4)-ethyl-thiosemicarba -zone, 1,3-diphenyl-4-benzal-pyrazol-5-one N(4)-ethyl-thiosemicarbazone and 1-Phenyl-3-methyl-4-phenylacetyl-pyrazol-5-one N(4)-ethyl-thiosemi -carbazone have been synthesized and characterized by elemental analyses, IR, 1H NMR spectra and single-crystal XRD.

第一部分合成了五个4-酰基吡唑啉酮缩4-乙基-氨基硫脲化合物：1-苯基-3-甲基-4-（4-溴）苯甲酰基-5-吡唑啉酮缩4-乙基-氨基硫脲(PM4BrBP-ETSC)，1-苯基-3-甲基-4-(4-甲基)苯甲酰基-5-吡唑啉酮缩4-乙基-氨基硫脲(PM4MBP-ETSC)，1-苯基-3-甲基-4-苯甲酰基-5-吡唑啉酮缩4-乙基-氨基硫脲，1，3-二苯基-4-苯甲酰基-5-吡唑啉酮缩4-乙基-氨基硫脲和1-苯基-3-甲基-4-苯乙酰基-5-吡唑啉酮缩4-乙基-氨基硫脲，其中前四个具有光致变色性质。

A higher yield(about 80%) can be obtained when 0.20-0.25 mol/1 of TUPMA is refluxed in 0.5 mol/l of NaOH solution at 75℃for 8h.

该产物的熔点为165.3℃，MS、~1HNMR和IR综合分析的结果确认，该产物的结构是4-二(1，2，4-三唑-5-硫酮基)-1，5-苯二甲酸。

According to the calculated results, a new atomic charge distributions of 2,3-diphenyl-tetrazole-5-thione was proposed with the sulfur atom and tetrazole ring having negative charges and the two phenyl-rings havingpositive charges.

对合成的3种[1，3，4]-噻二唑-2-硫酮-3，5-二取代物，用元素分析、红外光谱和紫外光谱等方法进行了表征，同时得到了其中两种化合物的晶体结构。

However, each of the five chemostats contained a variety of other bacteria capable of growth on IMP but not capable of hydrolyzing parathion, possibly interfering with the detection of FB at still lower abundance in the remaining three cultures.

但是， 每个五chemostats 包含了各种各样的其它细菌有能力在成长上在IMP 但不能水解对硫酮，可能干涉FB 的侦查在更低的丰盈在残余的三文化。

Both chemicals are toxic to medaka, in particular zpt, which also causes teratogenic effects such as spinal cord deformities in embryos at very low, sublethal concentrations.

所有化学物质对于青鳉来说都是有毒的，特别是锌羟基吡啶硫酮，这造成了青鳉的畸形，很低的亚致死的药量都会造成晶胚发育中脊椎的残缺。

Biological effects of the biocide zinc pyrithione, used in anti-dandruff shampoos and antifouling paints and the agricultural insecticide imidacloprid on japanese medaka fish were assessed in experimental rice fields.

用在抗头皮屑的洗发水和防污油漆以及专门用于日本青鳉的农业杀虫剂的有效成分锌羟基吡啶硫酮的生态影响在的水稻实验田接受评估。

The results showed that the dithione R is the most stable tautomer of all the tautomers in the form of isolated or hydrated isomers.

计算结果表明，2，6-二巯基嘌吟无论是孤立分子还是一水合物，其二硫酮式R是最稳定异构体。

This is the group of flatworms that cause schistosomiasis.

美国一个小组发现叫二唑啉硫酮的化合物可以定位血吸虫存活所需要的酶，这是一组引起血吸虫病的扁虫。

I can not make it blossom and suits me

我不能让树为我开花

When temperatures are above approximately 80 °C discolouration of the raceways or rolling elements is a frequent feature.

当温度高于 80 °C 左右时，滚道或滚动元件褪色是很常见的特征。