硫利达嗪

In this study, we investigated the enationmerization reaction of thioridazine, a commonly prescribed phenothiazine neuroleptic drug, in dynamic capillary zone electrophoresis.

中文摘要本篇论文以毛细管区带电泳法探讨抗精神病药物硫利达嗪对掌异构物间的动态学。

Enantiomeric separation of promethazine and thioridazine, unstable at room temperature, was performed at temperatures down to 3℃ on a lab-built-up CE instrument.

研究了手性药物异丙嗪和硫利达嗪的低温手性毛细管电泳分离，利用实验室自制的低温毛细管电泳仪，成功拆分了它们的混合物。

The fluorescence intensity measured was linear proportional with the concentration of free thioridazine hydrochloride in mixed solution over the range from 1×10-5 to 2×10-4 mol/L with the detection limit of 6×10-6 mol/L.

利用流动注射在线氧化结合在线透析采样技术建立了荧光法测定血浆中游离盐酸硫利达嗪的新方法，并将其应用于盐酸硫利达嗪与牛血清白蛋白作用机制的研究。

And we also proposed new methods to the study of thioridazine hydrochloride-BSA binding and methotrexate in dissolution testing based on dialysis sampling and flow injection on-line filtration, dilution techniques.

将方法应用于片剂中盐酸硫利达嗪含量的分析，测定结果与药典法一致。结果表明该方法具有检出限低、线性范围宽、精密度好以及分析速度快等特点。

In this thesis, we used this principle coupled with flow injection solid phase reactor on-line oxidation, solid phase extract and dialysis separation technology to establish the on-line oxidizing fluorometric method for determination thioridazine hydrochloride and methotrexate in table and plasma samples, respectively.

第二章：研究报告一、流动注射在线氧化荧光法盐酸硫利达嗪分析体系研究流动注射在线氧化荧光法测定药物中盐酸硫利达嗪含量本方法根据盐酸硫利达嗪的氧化产物具有强荧光这一性质，在磷酸介质中利用二氧化铅固相反应器在线氧化盐酸硫利达嗪并通过乙醇对其的增敏作用，建立了流动注射在线氧化荧光法测定盐酸硫利达嗪含量的新方法。

According to the fluorescence measurement results from mixed solution, the association constant estimated for thioridazine hydrochloride-BSA binding and the number of the binding site with Scatchard analysis were 1.2×104 L/mol and 0.98, respectively.

将盐酸硫利达嗪与牛血清白蛋白以不同比例混合并在37 ℃下培养，以流动注射透析采样技术从混合液中分离出游离盐酸硫利达嗪，在线氧化为强荧光化合物后测定其浓度；应用Scrathard方程分析所测数据，求得盐酸硫利达嗪和牛血清白蛋白的结合常数为1.2×104 L/mol，结合位点数为0.98；根据热力学参数推断，盐酸硫利达嗪与牛血清白蛋白之间以疏水作用力为主；进一步基于荧光猝灭现象和Fster非辐射能量转移理论，得到盐酸硫利达嗪小分子与牛血清白蛋白之间的能量转移效率( E =0.497)和结合距离( r 0=3.27 nm)。

Thioridazine hydrochloride is determinated by flow-injection system in which thioridazine hydrochloride is on-line oxidized into a strongly fluorescent compound firstly with a lead dioxide solid-phase reactor and the fluorescence intensity is measured with a fluorescence detector λex

三流动注射氧化荧光法结合在线透析采样研究盐酸硫利达嗪与牛血清白蛋白结合作用根据上述所建立的盐酸硫利达嗪含量测定方法，结合在线透析采样技术将蛋

Are the main products are: yellow phosphorus, phosphoric acid, sodium salt (one, two, three, four, five, six sodium), formic acid, sodium, a potassium, dispersants, S Lida triazine and more than 300 chemical reagent Products.

现主要产品有：黄磷、磷酸、磷酸钠盐（一、二、三、四、五、六钠）、甲酸、甲酸钠、甲酸钾、分散剂、硫利达嗪和300多个化学试剂产品。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。