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Keratin mutation predisposes to mouse liver fibrosis and unmasks differential effects of the carbon tetrachloride and thioacetamide models.

角蛋白突变诱发小鼠肝脏纤维化,揭示四氯化碳和硫代乙酰胺模型的的差别效应

Methods The model of medically intractable epilepsy was established by kindling of amygdale.

建立慢性杏仁核点燃癫痫模型,筛选出耐药组和有效组,通过侧脑室注射全硫代XIAP反义寡核苷酸,对照组分别注射生理盐水。

In order to solve the problem of produced waternot attaining quality standard and decrease pro cessing costs, the anthors synthesize a new type water processing chemicals and make quali tative analysis and effect test to the produot.

为了解决目前一些油田采出水处理达不到注水水质标准和降低处理费用的问题,我们合成了一种新型水处理药剂——二硫代氨基甲酸盐,并对合成的产品进行了定性分析和效果试验。

The lipid oxidation of the muscles of breast and leg in dry-cured duck during processing was studied by determination of the peroxide value,TBARS value,carbonyl compounds and conjugated dienes.

通过对过氧化值、硫代巴比妥酸值、羰基值和双烯值等氧化指标的测定,研究南京板鸭加工过程中各工艺点板鸭肌肉脂肪的氧化变化。

The application of them as catalysts in the asymmetric ring-opening of epoxides was investigated. Through the screening of the catalysts, we found that some of them demonstrated good asymmetric induction ability in this reaction.

我们对非手性二硫代磷酸在手性Schiff碱和Ti〓的存在下对环氧化合物的不对称开环反应进行了研究,对手性Schiff碱进行了进一步的筛选。

Reverse transcription polymerase chain reaction and western blot were used to detect the COCH and POU3F4/brn4 gene's expression. To investigate in vitro characteristics of COCH gene's expession, two factors were introduced in the culture medium of spiral ligament type Ⅰ fibrocytes respectively. Firstly, phosphorothionate-modified antisense oligodeoxynucleiotides to POU3F4/brn4 mRNA was applied to study the regulation effects of POU3F4/brn4 to COCH gene transcription.

引入人工合成的针对POU3F4/brn4基因mRNA的反义硫代磷酸寡聚脱氧核苷酸,干扰耳蜗螺旋韧带Ⅰ型成纤维细胞POU3F4/brn4的表达,免疫印迹检测反义干扰细胞POU3F4/brn4蛋白条带的强弱,RT-PCR检测反义寡核苷酸干扰细胞COCH基因转录水平的变化,观察POU3F4/brn4对COCH基因的转录调控作用。

RESULTS: At 12 weeks after infusing thioacetamide, pathological section showed that hepatic lobules were destroyed; hepatic cord was disordered; liver cells had adipose degeneration, with few necrotic cells; interstitial fibrous tissues were hyperplastic, and folioles in some fibrous tissues, inflammatory cell infiltration were detected. These were the symptom of hepatic fibrosis.

结果:注射硫代乙酰胺12周时,病理切片显示肝小叶结构破坏,肝索排列紊乱,肝细胞脂肪变性,有少许坏死,间质纤维组织增生,有部分伸入小叶,有炎性细胞浸润,为肝纤维化症状。

Above 98.5% of iron is removed by goethite method. Copper is separated using Na_2S_2O_3 as precipitator.

最后利用硫代硫酸钠从溶液中沉淀铜使镍保留在溶液中。

A novel lead ionselective polyvinyl chloride membrane electrode was prepared using 25,27di(2thiadiazolethiooxyethyl)26,28dihydroxyl5,11,17,23tetraptertbutylcalix[4]arene as the ionophore. The influences of the nature of plasticizers and the amounts of the incorporated ionophore and ionic additive on the response characteristics of the electrode were studied.

制备了以25,27二(2噻二唑基硫代乙氧基)26,28二羟基5,11,17,23四叔丁基杯\[4\]芳烃为载体的聚氯乙烯膜铅离子选择电极;研究了电极膜中增塑剂种类及载体和离子定域体含量对电极性能的影响。

The protein level of NF-kB in nucleus peaks at 8h after stimulating with LBP (200μg/ml). In addition, PDTC, an inhibitor of NF-kB, whose effective concentration for NF-kB inhibition without any toxicity on cells is up to 100μmol/L, can significantly block NO production induced by LBP.

另外,NF-κB抑制剂吡咯烷二硫代氨基甲酸盐作用于RAW264.7细胞90min,然后加入200μg/ml剂量的枸杞多糖对巨噬细胞进行刺激,发现PDTC在各个时间点(6、12、18、24h)都明显抑制枸杞多糖对巨噬细胞释放NO的诱导作用。

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推荐网络例句

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化,但却比去年同期高8%。

However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。