硫代

Methods 4-Hydroxybenzonitrile (2) as the starting material was transformed to 4-hydroxy-thiobenzamide (3) via thioformylation. And ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (4), which was synthesized via cyclization from 3, was treated with hexamethylenetetramine to generate the intermediate ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (5). The target compound febuxostat (1) was obtained from 5 by etherification, cyanidation, hydrolysis.

以羟基苯腈为原料，经硫代甲酰化得到对羟基硫代苯甲酰胺(3)，3经环合得到2-（4-羟基苯基）－4-甲基－噻唑－5-羧酸乙酯(4)，4与乌洛托品反应，得到中间体2-（3-甲酰基－4-羟基苯基）－4-甲基－噻唑－5-羧酸乙酯(5)，之后再经醚化、氰化、水解得到目标产物(1)。

Chapter 4 describes the synthesis, structural characterization and properties of anovel organic-inorganic hybrid compound, F〓〓BEDT-TTF =bis(ethylenedithiotetrathiafulvalene, which has been synthesized through thereaction of the pre-intercalate Fe〓PS〓〓(phen = 1.10-phenanthroline) with〓 Compared with the pristine FePS〓, the lattice spacing isexpanded by about 4.0〓, indicating that the molecular ring plane of BEDT-TTF isarranged parallel to the layer of the host.

通过红外光谱推测客体BEDT-TTF在层间以中性状态存在。X-线光电子能谱揭示在夹层化合物Fe〓PS〓〓中磷原子和硫原子在硫代亚磷酸根负离子簇中各存在两种化合价态，其中一种价态与纯主体或预夹层化合物〓〓中的磷原子和硫原子价态一致，而另一种价态却比纯主体FePS〓或预夹层化合物Fe〓中的磷原子和硫原子价态高。

Diallyl trisulfide was synthesized with a yield of 76.4% based on sodium thiosulfate, allyl bromide and sodium sulfide. And diallyl tetrasulfide was synthesized by the reaction of sulfur monochloride with ally1 mercaptan with a yield of 81.0%.

以硫代硫酸钠、烯丙基澳和硫化钠为原料，合成了二烯丙基三硫，产率为76.4%；以一氯化硫和烯丙硫醇为原料合成了二烯丙基四硫，产率为81.0%。

In the seventh chapter, the reaction of sodium hydrogen selenide with thiocarbamates and dithiocarbamates in ethanol as a selenium-containing reagent with good nucleophilic and reductive property were studied.

第七章进行了硒试剂NaHSe与硫代氨基甲酸酯和二硫代氨基甲酸酯的反应研究，并提出了反应的可能机理。

Company sulphur, sodium thiosulfate for the main field, sulphur, sales of 60000-80000 tons of sodium thiosulfate in sales of 8,000 tons, and annual sales of 67 million yuan, is the Northeast regional sales sulfur professional firms .

公司以硫磺、硫代硫酸钠为主营领域，硫磺年销售量为60000-80000吨，硫代硫酸钠年销售量8000吨，年销售额为人民币6700万元，是东北地区销售硫磺的专业公司。

Chemical method that is used chlorine sodium thiosulfate, the proportion of water per 10 kg plus 1 gram of sodium thiosulfate, stirring dissolved, you can use.

化学法即用硫代硫酸钠除氯，其比例为每10公斤水加1克硫代硫酸钠，搅拌溶解后，即可使用。

According to the reducibility of sodium thiosulfate ,the interference of sulfite is eliminated by formaldehyde and sodium thiosulfate is determined by indirect iodimetry with addition of excessive iodine.

根据硫代硫酸钠的还原性，以甲醛消除亚硫酸盐的干扰，加过量碘，间接法测定硫代硫酸钠。

By neutralizating, evaporating and crystallizing by-product sodium thiosulfate could be prep.

氧化后液的主要成分为硫代硫酸钠，通过中和、浓缩和结晶，可以副产出硫代硫酸钠。

In this paper, a series of 4,5-dithiacrown ether annulated 1,3-dithiole-2-thiones 8a~8d were prepared via condensing 4,5-bis-1,3-dithiole-2-thione (7) with 1,ω-dimercapto polyglycol derivatives in high dilution. The obvious template effect was found during the synthesis of 8c-8d.

在高度稀释条件下，经4，5-二溴甲基-1，3-二硫杂环戊烯-2-硫酮(7)和多缩乙二醇的1，ω-二巯基衍生物的缩合反应，方便地合成了4，5-位带二硫杂冠醚残基的2-硫代-1，3-二硫杂环戊烯的衍生物8a~8d，中间体硫杂冠醚8c~8d的合成中有明显的&模板效应&。

In this paper, a series of 4,5-dithiacrown ether annulated 1,3-dithiole-2-thiones 8a~8d were prepared via condensing 4,5-bis-1,3-dithiole-2-thione (7) with 1,ω-dimercapto polyglycol derivatives in high dilution. The obvious template effect was found during the synthesis of 8c-8d.

在高度稀释条件下，经4，5-二溴甲基-1，3-二硫杂环戊烯-2-硫酮(7)和多缩乙二醇的1，ω-二巰基衍生物的缩合反应，方便地合成了4，5-位带二硫杂冠醚残基的2-硫代-1，3-二硫杂环戊烯的衍生物8a~8d，中间体硫杂冠醚8c~8d的合成中有明显的&模板效应&。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。