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Abstract] Objective To assess the endothelium-dependent relaxation in patients with essential hypertension or hypertension smokers by color Doppler flow imaging.Methods With intermittent ultrasound imaging and power Doppler imaging,we measured endothelium-dependent relaxing function in 72 subjects 24 of whom with essential hypertension,24 of whom with both hypertension and smokingand the others as normal control.We measured the diameter of the superficial femoral and brachial arteries at rest,during reactive hyperaemia,re-test and after sublingual glyceryl trinitrate for evaluating the endothelium-independent dilatation in subjects.The level of plasma NO,ET,PGI2,and TXB2 were determined.

摘要] 目的探讨原发性高血压及高血压合并吸烟患者血管内皮依赖性舒张功能的改变方法采用彩色普勒高频超声的间歇成像和能量多普勒成像,对24例原发性高血压患者、24例高血压合并吸烟患者及24例正常血压无吸烟史者的血管内皮依赖性舒张功能,包括静息时血管内径、增加流量引起的血管舒张、硝酸甘油引起的血管舒张等,以及对血浆氧化氮、内皮素、血栓素B2(TXB2)和列腺环素(PGI2)等血管活性物质进行检测并比较分析。

Glyceryl trinitrate induced dilatation: GTN, high sensitive C reactive protein, tHcy, serum folate, red cell folate and lipids.

干预前、后分别检测血管内皮功能、血管平滑肌功能(硝酸甘油介导的血管平滑肌舒张GTN)、高敏C反应蛋白、血浆总高半胱氨酸、血浆红细胞叶酸盐和血脂。

Glyceryl trinitrate induced dilatation: GTN, high sensitie C reactie protein, tHcy, serum folate, red cell folate and lipids.

干预前、后分别检测血管内皮功能、血管平滑肌功能(硝酸甘油介导的血管平滑肌舒张GTN)、高敏C反应蛋白、血浆总高半胱氨酸、血浆红细胞叶酸盐和血脂。

Methods 30 patients with primary hypercholesterolemia administered with simvastatinfor 8 weeks.The changes of brachial artery intemal diameter under the reactive hyperaemia situation or after taking nitroglycerin were evaluated by CDFI before and after treated with SVT respectively.

对30例原发性高胆固醇血症患者给予辛伐他汀治疗8周,用CDFI测定治疗前后反应性充血时和含服硝酸甘油后肱动脉内径的变化。

Objective To investigate the effect of 17β-estrogen(E2), simvastatin and verapamil-nitrogtycerin solution on the synthesise of NO in human umbilical vein cells. Methods HUVECs were treated with 17β-E2, simvastatin and V-G solution for 30 min, 60 min and 120 min, respectively.

目的 观察17β雌二醇(E2)、辛伐他汀和异搏定一硝酸甘油复合溶液在短时间内对体外培养的人脐带静脉内皮细胞合成一氧化氮功能的影响。

In a sub-study, during week 3 of each dietary period, the ascular responses of 15 subjects to glyceryl-trinitrate and salbutamol were also studied.

亚组研究中,在每一饮食期第3周,研究15例受试者口服硝酸甘油和沙丁胺醇的脉管反应。

These include calcium antagonists, reserpine, tolazoline, and the artery widening drug nitroglycerine in ointment form.

这些措施包括钙离子拮抗剂,利血平, tolazoline ,以及动脉扩大药物硝酸甘油软膏形式。

The height, weight, blood pressure, fasting plasms glucose, fasting serum insulin, glycosylated hemoglobin (HbA1c), triglyceride, total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, and serum nitric oxide were measured before and after the therapy. The body mass index and homeostasis model assessment-insulin resistant index were calculated. The flow-mediated dilatation and endothelium independent dilatation were measured by high-resolution ultrasound.

治疗前后均检测身高、体质量、血压、空腹血糖、血浆胰岛素、糖化血红蛋白(HbA1c)、甘油三脂、胆固醇、低密度脂蛋白、高密度脂蛋白数(homeostasis model assessment-insulin resistant index, HOMA-IR),并用高分辨超声技术检测肱动脉血流介导的内皮依赖性舒张(flow-mediated dilatation, FMD)和硝酸甘油介导的非内皮依赖性舒张(endothelium independent dilatation, EID)。

Controlled hypotension was induced with nitroglycerin and esmololto maintain mean arterial pressure at 55-65 mmHg, which was stopped after the main surg...

手术开始时用硝酸甘油+艾司洛尔进行控制性降压,维持平均动脉压(60±5)mmHg。

Objective To investigate the effects of Thomas solution in combination with nitroglycerine of different concentrations on rat cardiac preservation for 8 h.

目的 探讨在托马斯液中加入不同浓度硝酸甘油对大鼠离体心脏保护8 h的效果。

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