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Objective To understand the distribution of state of endemic arsenism in Jilin province.

目的 查清吉林省地方性砷中毒病区的病情情况。

Objective To clinically study the effect of Ginkgo leaf on hepatic damage resulting from coal- burning arsenism and its mechanism.

目的观察银杏叶片对燃煤型砷中毒慢性肝损害的临床疗效,并探讨其作用机制。

The preserve method of micro whole-blood samples has also be put into practice in disease area of endemic arsenism.

随后,在本实验室已经建立的微量末梢血样SCGE分析方法的基础上,探索了微量血液样品的保存方法,并对此方法在地方性砷中毒病区进行了实践。

The decrease of the mRNA expression of MT in the patients with coal-burning arsenism may be related to the arsenism mechanism.

MMP-3 mRNA表达降低和TIMP-3 mRNA表达升高,可能是燃煤型砷中毒发病机制之一。

Methods Gastrocnemius muscle and sural nerve biopsy were made in 4 patients with middle or severe coal-burning arsenism.

目的探讨燃煤型砷中毒所致神经肌肉损害的临床病理特征。

It was found that Arsenism patients has higher degree of DNA damage than control person by micro-whole-blood-sample SCGE technique; v.

砷中毒病人的DNA损伤程度明显高于非病人,微量血样SCGE可以检测出这种差别的存在;5。

Objective: To study the relationship and the coordinating roles between cytokine levels and anti lipid peroxidation ability in arsenism patients.

目的: 探讨地方性砷中毒患者细胞因子水平与抗氧化能力的相关性。

DNA damage could be a biomarker of endemic arsenism, and SCGE was a sound technique to test this biomarker.

将DNA损伤作为地方性砷中毒的生物学标志具有可行性,SCGE是一种有效地检测这种生物标志的方法。

Methods DNA was extracted using the Phenol-Chloroform method from leukocytes of 51 patients suffered from coal-burnt arsenism and 52 healthy volunteers.

方法分别采集燃煤型砷中毒患者与正常人群外周血标本各51例和52例,采用酚一氯仿法提取DNA。

Results There were 28(32.3%) patients performed as neuropsychic disturbance which were classified into three types:the neurologic(13 patient;46.4%),the mental(6 patients;21.4%),the mixed of two(9 patients;32.2%).

结果在急性砷中毒的87例患者中出现神经精神障碍28例(占32.2%),其中对出现神经精神障碍的患者按临床表现分为:神经型13例(占46.4%)、精神型6例(占21.4%)和混合型9例(占32.2%)。

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