砷中毒

Human arseniasis is still the problem which has been paying close attention to so far in the internal and external medical field.

人类砷中毒至今仍是国内外医学界关注的课题。

MATERIALS AND METHODS: Using telomeric repeat amplification protocol assay and ABC immunohistochemical technique, the level of telomerase activation and PCNA expression were evaluated in 29 skin lesions of arseniasis patients and 10 cases of normal skin.

材料与方法：采用端粒重复序列扩增法和免疫组化ABC法检测29例砷中毒患者病损皮肤及10例正常皮肤组织中的端粒酶活性和PCNA表达情况。

Objiective: To explore wether urine porphyrins can be used as an exposure biomarker of endemic arseniasis.

目的：探讨尿中卟啉类化合物能否作为地方性砷中毒暴露性生物标志物并在实际工作中推广使用。

Objective In order to research arseniasis's mechanism on causing poisoning,especially resulting in skin carcinoma and search sensitive,practical monitoring index of DNA damage.

目的 探讨砷中毒的致癌机理及寻找灵敏、实用的DNA损伤监测指标。

Methods PCR-SSCP and PCR product cloning, sequencing were performed to detect mutation of p16 gene exon 2 in peripheral blood of 60 patients with arseniasis caused by coal-burning pollution,at the same time,PCR-based methylation assay was performed to analyze the methylation of p16 gene exon 1. Results No p16 gene exon 2 mutation was found in 60 cases.

采用聚合酶链反应-单链构象多态性分析和PCR产物克隆测序技术对60例砷中毒患者外周血中p16基因第2外显子突变情况进行检测，同时采用甲基化敏感的限制性内切酶方法对p16基因第1外显子甲基化情况进行分析。

In this paper, the distribution, type and geographically epidemic character of arsenism in China were reported.

本文报道我国地方性砷中毒病区的分布、类型和地理流行病学特征。

Objective To explore the influence of drinking water endemic arsenism on congenital deformity.

目的探讨饮水型砷中毒对出生缺陷或先天畸形的影响。

Objective To study the relationship between RBC immunity and lipid peroxidation of arsenism patient.

目的 了解燃煤型砷中毒患者红细胞免疫功能与脂质过氧化关系。

Methods: Genetypes were determined by PCR RFLP approaches in 99 healthy controls and 92 patients with endemic arsenism.

本研究分析了新疆奎屯地区汉族人群中DNA修复基因XPDLys751Gln多态和地方性砷中毒发病风险的关系，现将结果报道如下。

Abstract］ Objective To observe the clinical effect of treatment of endemic arsenism with organic selenium preparation.

摘要］ 目的观察有机硒制剂治疗地方性砷中毒临床效果。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。