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MMPs are usually secreted as latent, inactive proenzymes, which need to be activated (Fig 1 ), and/or are bound to their native inhibitors, the tissue inhibitors of metalloproteinases.8 Activation may involve proteolysis and/or oxidation of the latent enzyme.8 Proteolytic activation of the proenzymes cleaves the propeptide sequence, which masks the active site of the latent enzyme.

金属蛋白酶常以无活性的酶原方式分泌,而后者要么需要被激活要么与附近的或组织中金属蛋白酶抑制物结合。激活作用包括了具有潜在酶的蛋白水解作用或氧化作用。酶原的蛋白水解激活作用能将掩盖活性部位的潜在酶的前肽序列破坏。

The plasminogen/plasmin proteolytic system participates in a wide variety of extracellular matrix degradation.

纤维蛋白溶解系统的胞浆素具有造成细胞间质裂解,产生组织破坏的特性,可能是牙髓致病路径之一。

The relationship between MFs and MTs in the organization of PPB was investigated in garlic root tip cells subjected to treatment with cytochalasin D , latrunculin A and phalloidin .

用微丝特异性解聚药物(细胞松弛素CD和LAT A)以及微丝稳定药物处理大蒜根尖分生组织细胞的实验结果表明:微丝被破坏后,导致了早前期微管带宽度明显增加,Ph处理则对早前期微管带的宽度无影响。

Results: 1. The three-dimension (3D) model reconstructed by Micro-CT scan data objectively reflected the real contour and the pulp cavity figure of the tooth.

实验结果: 1。本研究采用Micro-CT扫描,准确、安全、无创伤、分辨率高,所得到的断层信息可以较清晰的显示牙体组织及根管系统等结构,又不破坏标本的完整性。

A terrible accident occurred, unleashing a mutant tissue-destroying bacterium into the surrounding area.

在一次恐怖的事故中,一种破坏生物组织的突变细菌被释放到周围地区。

Diaspididae is one of important pests in agriculture, forestry and ornamental plants. It not only pierces and sucks plant sap, destroys plant green organizations, but also pollutes the plant of leaf and fruit surface, affects plant of photosynthesis, leads to the plant of deformities, wither and die when it occurred largely.

盾蚧Diaspididae是农林、观赏植物的重要害虫之一,它不仅刺吸植物汁液,破坏植物绿色组织,而且当它大量发生时常污染植物叶面和果实,影响植物的光合作用,导致植物畸形、枯萎、死亡。

MRE, developed at the Mayo Clinic, uses a modified form of magnetic resonance imaging to effectively measure the hardness or elasticity of the liver.

肝脏可由于很多疾病造成其细胞破坏并发展成瘢痕组织或纤维化。MRE是MRI基础上发展而来的,并且可以有效测量肝脏的硬度和弹性。

This would have been enough to form a sizable gendarmerie, but the Home Returning Corps defeated their own purposes by pocketing most of the self-defense funds.

这足够组织一支规模可观的宪兵队了。但是,还乡团把这笔旨在加强防卫的款项的大部分塞到自己的腰包里,从而破坏了他们自己的计划。

For the better part of a week shock troops of the Primeiro Comando da Capital, a prison-based criminal organisation, wrought havoc on S o Paulo, killing policemen, firebombing buses and banks and bringing the city to a virtual standstill. The police struck back with even greater ferocity.

不到一个星期里令人震惊的首都第一司令部的犯罪组织行动给圣保罗造成了极大破坏,杀死警察,焚烧公共汽车和银行,使城市陷入了瘫痪。

We hold these truths to be selfevident, that all men are created equal and independent; that from that equal creation they derive in rights inherent and inalienables, among which are the preservation of life, and liberty and the pursuit of happiness; that to secure these ends, governments are instituted among men, deriving their just powers from the consent of the governed; that whenever any form of government shall become destructive of these ends, it is the right of the people to alter or to abolish it, and to institute new government, laying its foundation on such principles and organizing it's powers in such form, as to them shall seem most likely to effect their safety and happiness.

我们认为下面这些真理是不言而喻的:人人生而平等,造物者赋予他们若干不可剥夺的权利,其中包括生命权、自由权和追求幸福的权利。为了保障这些权利,人类才在他们之间建立政府,而政府之正当权力,是经被治理者的同意而产生的。当任何形式的政府对这些目标具破坏作用时,人民便有权力改变或废除它,以建立一个新的政府;其赖以奠基的原则,其组织权力的方式,务使人民认为唯有这样才最可能获得他们的安全和幸福。

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推荐网络例句

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。