破伤风

Several antigens of pathogenic microorganisms, such as C subunit of tetanus toxin and the Brucella abortus ribosomal protein L7/L12, were successfully expressed in Lactococcus lactis.

破伤风毒素片段C、布氏杆菌L7／L12蛋白等多种病原微生物抗原已成功在乳酸乳球菌中表达，并已证明部分重组乳酸乳球菌作为黏膜免疫疫苗可以同时刺激局部黏膜免疫应答和系统免疫应答。

Tetanus toxoid with or without tetanus immunoglobulin, as appropriate, should accompany wound treatment postdisaster.

灾难后的伤口处理，应予以注射破伤风疫苗（适当选择有或没有破伤风免疫球蛋白的疫苗）。

Further study was aimed at improving the stability of tetanus toxoid in microspheres by co-encapsulation of various additives known for their stabilizing effect on protein conformation and activity.

接下来的工作是考察破伤风类毒素的稳定性，以及在微球中共同包载能够稳定蛋白质构象和活性的附加剂，提高微球中破伤风类毒素的稳定性。

Moreover, the formulation composed of a mixture of different microspheres provided an immune response very similar to that of the three-dose of soluble tetanus toxoid.

微球引起的抗体显著高于破伤风类毒素溶液一次免疫的抗体水平，与破伤风类毒素溶液3次免疫的效果相似。

The antibody levels elicited by different formulations, including individual and mixture of microspheres, soluble tetanus toxoid and aluminum hydroxide adsorbed tetanus toxoid, in mice and guinea pigs for 1 year were examined. And anamnestic responses to a low dose booster 1 year after priming to mice were also examined.

考察了单独的微球和混合的微球、破伤风类毒素溶液及氢氧化铝吸附的破伤风类毒素，这几种不同的制剂在小鼠和豚鼠体内的免疫效果。

Infectious and contagious diseases like polio, malaria, neonatal tetanus, diphtheria, measles, rubella, mumps, whooping cough and dengue have been eradicated; others like tetanus, meningococcal meningitis, hepatitis B, leprosy, hemophilus meningitis and tuberculosis are fully controlled.

象 脑灰质炎、疟疾，新生破伤风、白喉、麻疹、风疹、腮腺炎、百日咳和登革热一样的传染病已经被根除；象破伤风、流行性脑脊髓膜炎、B肝炎、麻疯病、流行性脑脊髓膜炎、血友症（一种出血不止的病症——译者注）和肺结核一样的其它疾病也完全被控制。

Early diagnosis and treatment for malaria in malaria-endemic areas (within 24 h of onset of fever, using artemisinin-based combination therapy for falciparum malaria).

正确清洁和护理伤口。灾难后的伤口处理，应予以注射破伤风疫苗（适当选择有或没有破伤风免疫球蛋白的疫苗）。

Experiencing tetanus does not itself produce immunity to a second infection. People who have had tetanus should still be immunised when they have recovered.

在经历了破伤风本身并不产生免疫力的第二个感染的人谁曾破伤风仍应该免疫时，他们已康复。

The invention provides a human McAb to tetanus toxin, being a human antibody, which consists of an antibody variable region and an antibody constant region or not, having the ability of neutralizing the tetanus toxin, with the variable region gene and protein sequence indicated as the sequence table 1. The invention is characterized in that the antibody can not induce obvious allergic reaction, has higher titer and longer effect without any animal virus pollution, and can be produced in an unlimited quantity, which also provides the relating biological functions, the testing methods, the manufacturing method and the application.

A 本发明提供一种人源抗破伤风毒素单克隆抗体，其为人源抗体，包括抗体可变区，该抗体包括或不包括抗体的恒定区，该抗体具有中和破伤风毒素的能力，抗体可变区的基因和蛋白质序列如序列表1所示；其具有不会诱发明显的过敏反应，有较高的效价且长效，产品无动物病毒污染，可以无限量地生产；本发明还提供了其生物功能、测定方法、生产制造方法及其应用。

Although 91% of subjects 6 to 11 years old had protective levels of both diphtheria and tetanus antibody, this proportion declined with advancing age, and was only 30% among persons 70 years old.

虽然有91％的年龄在6到11岁的被研究者存在足够预防白喉和破伤风发生的保护性抗体浓度，但是这个比例随著被研究者年龄的增加而逐渐降低，到了70岁只有30％的人体内含有可以预防白喉和破伤风发生的抗体浓度。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。