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The National Cancer Institute, the National Institutes of Health, and Corixa supported this study. Corixa employs one of the authors and has various financial arrangements with several other authors. Some of the authors report potential financial conflicts of interest with GlaxoSmithKline. Two authors receive royalties from patents they jointly hold on anti-CD20 radioimmunotherapy for lymphoma, and they have been expert witnesses in defending these patents.

国家癌症机构、国家卫生研究院及Corixa赞助这项试验;Corixa雇用其中一位研究人员,而且许多其他研究人员接受该公司的资金赞助;某些研究人员表示与葛兰素药厂有潜在资金上的冲突;两位研究人员接受来自病患的专利权费,这两位共同拥有抗CD20放射线免疫疗法治疗淋巴瘤的专利,且他们一直是保护这些病患的专家证人。

The National Cancer Institute, the National Institutes of Health, and Corixa supported this study. Corixa employs one of the authors and has various financial arrangements with several other authors. Some of the authors report potential financial conflicts of interest with GlaxoSmithKline. Two authors receive royalties from patents they jointly hold on anti-CD20 radioimmunotherapy for lymphoma, and they have been expert witnesses in defending these patents.

国家癌症机构、国家卫生研究院及Corixa赞助这项试验;Corixa雇用其中一位研究人员,而且许多其它研究人员接受该公司的资金赞助;某些研究人员表示与葛兰素药厂有潜在资金上的冲突;两位研究人员接受来自病患的专利权费,这两位共同拥有抗CD20放射线免疫疗法治疗淋巴瘤的专利,且他们一直是保护这些病患的专家证人。

Finally, since a lot of valuable achievements in p-y curve model have been made and put into practice in the overseas design of pile foundations on liquefiable grounds whereas the domestic research is still at the start with focuses laid on experiments, some thoughts and understandings on the p-y curves are put forward in this review to elucidate effective technical approaches.

液化土p-y曲线的模型研究国外已取得不少很有价值的科研成果并开始用于桩基设计中,而国内才刚刚起步且以试验研究为主,基于这个事实,提出了对曲线模型研究的若干建议与认识,为曲线模型研究提供一些技术思路。

Based on the spaceflight technology innovation program of"Research on the Testing Method of Reliability----Research on the Fault Diagnostic Expert System and Neural Network"and the Pre-Research Defense Projects of"Research on longevous service and high reliability of Satellites"of the National tenth-five-year plan, taking attitude control system of a satellite as object, the theories and the applications of the neural networks and expert system in the fault diagnosis are studied in this dissertation.

本文以航天技术创新基金项目&可靠性试验方法研究——故障诊断的专家系统神经网络技术研究&和国家武器装备&十五&预研项目&卫星长寿命高可靠性技术&为背景,以卫星姿态控制系统为研究对象,在理论和实践两个方面对神经网络和专家系统相结合的故障诊断技术及其在卫星中的应用进行了研究。

The sort of new drug of TCM,the declare of new drug of TCM and the manufacture of new drug of TCM(including technics research, establishment of quality standard, pharmic research, toxicology research and clinic research) are introduced systematically.

该课程系统介绍中药新药分类、申报和研制的基本知识、技能,主要内容包括中药新制剂工艺研究、质量标准的制定及稳定性试验、药效学研究、毒理学研究、临床研究。

Orange-spotted grouper is a benthic protogynous marine fish with sex inversion. It is one of the most important culturing fish in the southeast of Asia. As in other vertebrates, its growth is mainly controlled by growth hormone . Few data are available concerning the regulation of GH in grouper. In this paper, the regulation of growth hormone release from pituitary of orange-spotted grouper and its mRNA level was determined by radioimmunoassay and RNase protection assay.

中文题名斜带石斑鱼生长激素分泌及其基因表达调控的研究副题名外文题名 Regulation of growth hormone and its gene expression in orange-spotted grouper,Epinephelus coioides 论文作者冉雪琴导师林浩然学科专业水生生物学研究领域\研究方向学位级别博士学位授予单位中山大学学位授予日期2003 论文页码总数140页关键词生长激素基因表达石斑鱼馆藏号BSLW /2003 /Q959 /39 应用分子克隆技术,构建了斜带石斑鱼生长激素(Growth hormone,GH)基因重组质粒,在大肠杆菌细胞中获得高效表达,亲和层析纯化斜带石斑鱼GH融合蛋白做为抗原,免疫家兔制备特异性抗体,通过酶联免疫实验、放射免疫测定、离体脑垂体静态孵育和液相杂交/核糖核酸酶保护试验及化学发光检测技术,研究了斜带石斑鱼GH分泌及其mRNA表达的调控机制,对于斜带石斑鱼的生长、繁殖、人工养殖等具有重要意义。

The studies was proceeded on the the supercritical CO2 extraction technique of rotenone from Tephrosia vogelii. The extraction influences of technology conditions were systematically groped, The research results were listed as follows:1 The analysis method applied in this paper has been proved to be suitable to technology research of the studies on the SC-CO: extraction technique of rotenone from Tephrosia vogelii. 3 indexes, extraction ratio of rotenone. extraction ratio of total compounds and rotenone content percent in total compounds weight, were carried out with HPLC quantitatively determination combined with the sample weight loss after extraction. With these 3 indexes. The extraction influences of technology conditions were evaluated by synthesis. Then the best technology conditions were ascertained for different extraction aims.2 The pretreatment of rough material should be needed before extraction. Comminuting the material to 0.28mm size is most fit to SC-CO: extraction.3 Firstly static extracting 20 min then turn to dynamic doing is the better extraction mode than other ones.4 The orthogonal experiment was conduct with 3 factors and 5 levers.

本论文通过对非洲山毛豆SC-CO_2萃取中影响萃取效果的工艺条件的研究,初步得出如下结果:(1)本论文中所采用的萃取效果评价方法适宜于非洲山毛豆中鱼藤酮的超临界流体萃取技术研究,该方法具体为:HPLC定量分析非洲山毛豆SC-CO_2萃取物中的鱼藤酮含量,再结合萃取前后处理样品的重量损失,得出鱼藤酮萃取率、萃取所得粗物质萃取率和粗物质中鱼藤酮含量三个参数,以此三个指标综合评价萃取条件对萃取效果的影响;(2)通过对原料粒度对萃取效果影响的研究,结果表明SC-CO_2萃取非洲山毛豆复叶中的鱼藤酮,原料粉碎成30目粒度叶粉时萃取效果较好;(3)通过对萃取方式与萃取效果之间关系的研究,结果表明SC-CO_2萃取非洲山毛豆中鱼藤酮应采用先静态后动态的萃取方式,静态萃取时间为20min;(4)通过温度、压力和CO_2流量三因素五水平的正交试验,结果表明温度是最主要的影响因素,压力因素对鱼藤酮萃取率的影响程度高于CO_2流量,而对于粗物质萃取率和粗物质中鱼藤酮含量CO_2流量因素高于压力。

Seeing that the basic researches of the method of metal magnetic memory insufficiently, this text has done the following work mainly:(1)Studied the basic theory of the method of metal magnetic memory;(2)Studied the signal of metal magnetic memory of samples both anneals and not anneals in natural magnetic field and drive magnetic field under the drawn loads;(3) Studied the signal of metal magnetic memory of anneals samples in three magnetic fields under the drawn loads.

鉴于其基础研究工作不足,本文主要做了如下工作:(1)系统地研究了金属磁记忆检测技术的基本理论:(2)研究了退火试件和未退火试件在自然磁场和激励磁场环境中进行拉伸的磁记忆信号;(3)研究了退火试件在三种磁场环境中进行拉伸试验的磁记忆信号。

The paper takes the steam turbine valve actutors and control systems as the object of study, and the fast valving of regulating valves in case of electrified wire netting failure plays an important role. The disadvantages of electro-hydraulic control systems for steam turbine available are discussed, and the principle of the new system and its design method are presented, experimental study and theoretical analysis results concerning the steam turbine electro-hydraulic control system based on the new combination principle are reported in this paper.

本文把汽轮机蒸汽阀门电液执行机构及控制系统作为主要的研究对象,尤其是针对于电网故障时,调节汽门快关控制问题进行了深入的研究,指出现有汽轮机电液控制系统存在的问题,在继承和总结前人研究的基础上,提出了汽轮机电液控制系统组成原理的新思想与系统设计的新方法,对基于这种新原理的汽轮机电液控制系统进行了系统的理论分析与试验研究。

In this experiment,nad4 and cox1 genetic variation of cestodes were firstly studied.Genetic variation and DNA polymorphism of mitochondria were carried out from mitochondrial gene.So the effective genetic markers were found which studied molecular taxonomy and Phylogenetic relationship of cestodes.This study have filled in the blank space of research that was related to China\'s cestodes mitochondrial genome research.

本试验首次对绦虫nad4和cox1基因的遗传变异情况进行研究,从线粒体基因的角度,开展绦虫线粒体遗传变异和DNA多态性方面的研究,找到了研究绦虫分子分类学、种群遗传关系有效的遗传标记,填补了我国寄生绦虫线粒体全基因组相关研究的空白。

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