研究动物

Advance basic research has confirmed that the alkaloids extracted from thunberg fritillary bulb which is widely used in clinical medicine in vitro and in animal experiments have reversed MDR of leukemia. It will increase resistance of acute leukemia cells anticancer drug concentration and lower resistance the expression of Pgp. Pre-Clinical Experimental Research also shows that the conventional chemotherapy combined with the powder of thunberg fritillary bulb for the treatment of acute leukemia. Clinical complete response rate was higher, especially for patients with refractory or relapsed leukemia patients better clinical remission rate. In addition, Caladium particles Slices with chemotherapy in the treatment of RAL Clinical studies also show the Chinese refractory leukemia improve clinical efficacy safe and reliable.

先期基础研究已证实：临床常用的化痰散结中药浙贝母提取的生物碱体外及动物实验均有逆转白血病多药耐药的生物活性，能增加耐药的急性白血病细胞内抗癌药物浓度，降低耐药蛋白Pgp的表达；临床预实验研究也表明，常规化疗方案配合浙贝母粉用于急性白血病临床治疗，其临床完全缓解率明显高于对照组，尤其对难治及复发白血病患者临床缓解率更佳；此外，单药浙贝母颗粒配合化疗治疗RAL的临床研究亦显示中药在提高难治性白血病临床疗效方面安全可靠。

The journal publishes reports on clinical and experimental research in autoimmunity, as well as basic research, molecular, cellular and whole organism levels, in areas such as immunogenetics, immune cell signaling, molecular markers of autoimmune diseases, immune interventions, new animal models, transplantation, stem cell therapy, and gene therapy.

杂志刊载自身免疫的临床和实验性研究报告，以及基础研究，分子，细胞和整个有机体水平的研究，涉及领域包括免疫遗传学，免疫细胞信号，自身免疫性疾病的分子标记，免疫干涉，新动物模型，移植，干细胞治疗，和基因治疗。

Methods: Study the newly found cell with the weak silver carbonate staining method of del Rio-Hortega. Using transmission electron microscopy, compare the newly found cell with the atypical cell found by Marc Lenoir and Philippe Vago, and extend young SD rat model to adult SD rat, young and adult Wistar rat,and extend drug of Neomycin to Amikacin to study the universality.

采用经典的小胶质细胞特殊染色方法——银染法(Hortega氏碳酸银法)对大鼠耳蜗药物损伤后出现的新细胞进行研究；通过透射电镜与Marc Lenoir和Philippe Vago实验动物模型中的"非典型细胞"进行了比较与扩展研究；运用逆转录PCR技术检测耳蜗基底膜上神经干细胞标志物nestin的表达情况，对新细胞的来源及其与神经干细胞或nestin的前体细胞的关系作进一步研究。

Molecular systematics on germplasm resources of oak silkworm, Antheraea pernyi, including genetic diversity, cultivar taxonomy and microevolution within species, were investigated using Random Amplified Polymorphic DNA , mtDNA sequence analysis and population genetic analysis.

中文题名柞蚕种质资源的分子系统学研究副题名外文题名 Molecular systematics on germplasm resources of Antheraea pernyi 论文作者刘彦群导师鲁成向仲怀学科专业特种经济动物饲养学研究领域\研究方向蚕的生物技术与遗传育种学位级别博士学位授予单位西南农业大学学位授予日期2003 论文页码总数143页关键词蚕种质资源柞蚕馆藏号BSLW /2003 /S885 /1 柞蚕业是我国的一项传统产业，在现代国民经济中仍然具有资源配置、经济和生态的合理性，有着广阔的发展前景。

Reproduction is a key process, which highly influences the economic efficiency of pig production. Traditional quantitative genetics plays a very important role in animal breeding. Selection for increased number of piglets born has been employed in pigs with only limited success because of the low heritability, the late expression in life and the sex-limited nature of reproductive traits.

中文题名猪ESR和FSH-β位点对猪繁殖性状的调控及其调控机理的研究副题名外文题名 Regulations of reproductive traits by ESR and FSH-β loci and the mechanisms involved 论文作者李凤娥导师熊远著院士学科专业动物遗传育种与繁殖研究领域\研究方向猪的分子遗传育种学位级别博士学位授予单位华中农业大学学位授予日期2002 论文页码总数115页关键词猪繁殖性状馆藏号BSLW /2003 /S828 /2 繁殖是养猪生产过程中的关键一环，该环节成功与否直接影响整个养猪业的经济效益。

For example, in a study published last year in the Proceedings of the National Academy of Sciences a group of researchers looked at crustaceans (crabs, shrimps, woodlice and so on) over the past 550m years and found far more examples of groups of species evolving towards complexity than in the other direction.

举个例子，去年美国国家科学院公布的一项研究里，一群研究人员对生活在过去5.5亿年里的诸如螃蟹、虾、节肢动物有树虱之类的甲壳纲动物进行了研究。他们发现，更多的物种群体是朝着复杂而不是别的方向进化的。

The 12940 bp nucleotide sequence of the mitochondrial genome of a brachyura dacapod, Eriocheir japonica sinesis, was determined. The arrangement of 27 genes of the mitochondrial DNA differs from that of the mitochondrial DNA in all other arthropods studied.

中文题名中华绒螯蟹线粒体基因组与16S rDNA遗传标记研究副题名外文题名 The mitochondrial genome of the mitten crab，Eriocheir japonica sinensis(Crustacea：Decapoda：Brachyura) and genetic marker from mitochondrial 16S rDNA 论文作者孙红英导师周开亚教授学科专业动物学研究领域\研究方向学位级别博士学位授予单位南京师范大学学位授予日期2002 论文页码总数80页关键词蟹中华绒螯蟹线粒体基因组遗传标记馆藏号BSLW /2003 /Q959 /30 测定了短尾类十足目动物中华绒螯蟹的线粒体基因组12940 bp的核苷酸序列。

The achievement of this project can be briefly summed up as following:(1)the carbon contributing to karst processes mainly comes from ecological system itself under the condition of existence of vegetation and soil covers;(2)results indicates that the depositing processes of rainfall to CO2 is an important "sink" to global carbon cycle;(3)owing to the differences of vegetation and surface covering, the adjusting effect of ecosystem to environmental humidity, temperature and CO2 concentration near surface air which indicates different benefit of preventing water and soil from lose is marked;(4)the preponderant species of vegetation in the karst ecosystems which have different kinds of carbonate rocks are obviously variant, and this situation results to the clearly differences of the micro － habitat , structure of surface cover and water holding capacity;(5) the relevant study showed that the carpophagous animals and birds make a important role in the spreading of vegetation seeds. The designed experience for the study of seed reservoir was not able to obtain a satisfactory result.

主要研究成果包括：通过对表层系统碳库的研究，认为在有土壤和植被覆盖时，岩溶作用过程中的碳主要来自生态系统本身而不是母岩；降雨对大气碳具有重要&沉淀&作用，是碳的一个重要汇；不同植被类型表层岩溶系统对系统水份、空气湿度、气温、土温和近地表 CO2浓度等具有明显调节作用，具有不同的水土保持效益；不同母岩的岩溶生态系统的植被优势种、属差异明显，由此形成的小生境、地被物及其持水性差异巨大；对典型岩溶表层系统种子库的试验研究没有取得满意结果，但食果动物、鸟类对种子传播起到一定作用。

This article explains the reoxygenation injury problems in immature myocardial at home and abroad literature,through the reoxygenation injury in cell-biology research and a large number of animal model of test,medical research and clinical research,recognize that the reoxygenation injury is the rootstock of postoperative heart and lung disorders in cyanotic congenital heart disease.

本文就未成熟心肌再氧合损伤的问题结合国内外文献，通过再氧合损伤的细胞生物学研究和大量的动物模型试验研究和医学临床研究，认识到再氧合损伤是发绀型先天性心脏病术后心肺功能紊乱的根源。

The fragments of mtDNA COI gene were sequenced for 11 species from 3 subfamilies of Cypraeidae, and the homologous sequences of another 17 species of Cypraeidae were downloaded from GenBank.

首先，本研究对腹足纲部分类群的分子系统学研究进展及宝贝科动物系统进化研究中存在的若干问题进行了较为系统的评述。

By the time of its fall, most of the prisoners were writers who had written against the corruptions of the government.

到它被攻陷的时候，里面多数的犯人是写了反对政府贪污文章的作家。

The most obvious variation to ovum morphological character was that the color was changed from light green to sepiaceous in embryonic development, and all the ovums were almost hatched after 96h.

在胚胎发育过程中卵的形态特征最明显的变化是颜色从淡绿到深褐色，卵在发育96h后卵基本全部孵化。