研究动物

Objective:To study the content of tyrosinase in the blood and hemorrheology in vitiligo animal pathological pattern.

目的：研究化学脱色法复制白驳风模型动物血液中酪氨酸酶含量及血液流变性指标的变化。

Each medicine used in the study totally has obivious effect on lens sodium-pump. Either on the molecular and cellular level or on the histological and organic level , they all have their distinctive demonstration. 1.Ouabain、Digoxine、DMSO decrease the expression of αsubunit of sodium pump on mRNA level , the cell morphology and ultramicroscopic structure demonstrated destructive effect,it indicates the cause of cataract of the medicines.2.D-thyroxine、Amphotericin B、Vitamin E increase the expression of αsubunit of sodium pump on mRNA level ,from the demonstration of the cell morphology and ultramicroscopic structure ,it indicates the medicines have protective or anti-distructive effect on lens.3.The medicines have isoform-specific action on lens sodium-pump,it indicates exploitting isoform-specific medicine has a promising clinical application.4. Lens sodium-pumps are inhibited probably lead to cataract, so in clinical medication, especially to the cardiovascular doctor, while he is using the sodium-pump inhibitors, he should pay more attention to adjust the dosage and duration of the drug therapy. 5. To creat the animal model of cataract through inhibiting lens sodium-pump, whether it can be a kind of classical method or not, it is worthy of further research.

本研究所选用的药物对晶状体钠泵均有明显的影响作用，在分子水平、细胞水平、组织器官水平均有特异的表现：1、哇巴因、地高辛、二甲基亚砜三种药物可降低晶状体钠泵α亚单位在 mRNA水平的表达，在细胞形态和超微结构上表现为损伤效应，提示了其潜在的导致白内障的可能。2、D甲状腺素、两性霉素B、维生素 E三种药物可升高晶状体钠泵α亚单位在 mRNA水平的表达，从细胞形态和超微结构上的表现，提示了其对晶状体有保护作用或抗损伤效应。3、药物作用于晶状体钠泵具有重整异构特异性，提示了开发出特异的具有重整异构作用的药物是极有临床应用前景的。4晶状体钠泵抑制后可能导致白内障的发生，故临床用药，尤其是心内科医生在使用这些钠泵抑制剂时应注意调整用药剂量及药物疗程。5 通过抑制晶状体钠泵来制作白内障动物模型能否成为一种经典的制作方法，还有待于进一步研究。

"Since DM is a multisystemic disease, it is difficult in humans to uncouple the specific molecular abnormalities which lead to cardiac disease from pathological events in other tissues. The fact that this inducible model develops many of the characteristic features of DM heart disease is remarkable and validates the use of this approach." He added, however, that therapeutic approaches developed in animal models might turn out to be ineffective during human clinical trials.

因为DM是一种多系统性疾病，在人类难以从其他组织的病理解开会导致心脏疾病的特定分子异常，事实上，是这个归纳模式发展出许多DM心脏疾病的特徵，这些是重要且对研究有用的，不过，动物模式发展的治疗方式，可能在转成人体临床试验之后变得无效。

In the past, evolutionary biologists contemplating the absence of wheels in nature agreed that the explanation was not undesirability: wheels would be good for animals, just as they are for us.

从前，研究自然界没有轮子的进化论生物学家都同意不能用无此需要来解释这种现象：轮子对于动物会像对于我们人类一样有好处。

Evolution and Wheels In the past, evolutionary biologists contemplating the absence of wheels in nature agreed that the explanation was not undesirability: wheels would be good for animals, just as they are for us.

从前，研究自然界没有轮子的进化论生物学家都同意不能用无此需要来解释这种现象：轮子对于动物会像对于我们人类一样有好处。

Methods Thirty Japan white rabbits (30days old) were divided into 3 groups in random. Group Ⅰ was unoperated controls, Group Ⅱ was unrepaired controls, Group Ⅲ was repaired with Tennison Triangular. All the animals were sacrificed and measured on the clean skulls directly at 26 weeks postoperativly (30 weeks old).

该研究采用30只(30天龄)日本纯种长耳白兔，随机分成正常对照组(10只)、造裂组(10只)、Tennison法修补唇裂组(10只)，术后26周(30周龄)，处死动物，行头颅测量。

Group Ⅰ was unoperated controls, Group Ⅱ was unrepaired controls, Group Ⅲ was repaired with Tennison Triangular. All the animals were sacrificed and measured on the clean skulls directly at 26 weeks postoperativly (30 weeks old).

该研究采用30只(30天龄)日本纯种长耳白兔，随机分成正常对照组(10只)、造裂组(10只)、Tennison法修补唇裂组(10只)，术后26周(30周龄)，处死动物，行头颅测量。

For small ponds the seasonal dynamics of zooplankton community structure are relatively unstudied, as are any mechanisms underlying these dynamics.

就小型池塘浮游动物群体结构的季节性动力学研究是相对少的，例如这些动力学中潜在的一些机制。

Previous research had shown that laboratory animals given 30 percent to 50 percent less food can live up to 50 percent longer.

以往的研究表明，实验动物给予百分之三十至百分之五十不到食物可以辜负百分之五十更长的时间。

In order to solve the main problem of incomplete of denervation, a new method of proximal gastric vagotomy was designed for experimental observation on mongrel dogs.

本文针对胃近端迷走神经切断术中迷切不完全这一原因，设计一种新的PGV手术，应用于动物实验研究。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新