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We further evaluated the synergistic cytotoxicity of TRAIL in combination with actinomycin D, cisplatin and paclitaxel in A549 cell lines in vitro and in vivo.

本实验选择了人肺腺癌A549细胞瘤株作为我们实验研究的对象,通过TRAIL对人肺腺癌A549细胞诱导凋亡研究,在A549的荷瘤裸鼠的动物模型上研究了其体内的抗肿瘤活性,并进一步研究了TRAIL与化疗药物放线菌素D(actinomycin D,Act D)、紫杉醇和顺铂(cisplatin,CDDP)的联合作用对人肺腺癌A549细胞的体外协同抗肿瘤活性,通过化疗药物协同增强TRAIL抗肿瘤活性作用机制的初步研究,为降低临床化疗药的用药量,减轻其对机体的不良反应提供一定的理论基础。

The introduction is a review of literature, including a review of the research about advertorial in Chinese, a conclusion of the achievements and limitations, and then a proposal of the purpose and problems to be discussed in the thesis.

绪论部分是"软文"研究的综述,回顾了"软文"研究现状,通过对批评性研究和非批评性研究的梳理,总结成果与不足,进而提出本文的研究目标和问题,是本文的起点。

Geological condition is the important factors in study on tunnel excavating disaster inevitably. From the aeolotropy of hard rock of tunnel engineering region, the stress distribution of several kinds of fault to the water gushing of tunnel, the type of geology disaster involved in macrocharacter, main control factors, disaster mechanism and control strategy in tunnel excavating are studied systematically in this thesis.

中文题名隧道开挖地质灾害规律与防治对策研究副题名外文题名 Study on tunnel excavating geology disaster regular and control trategy 论文作者杜炜平导师古德生院士学科专业岩土工程研究领域\研究方向学位级别博士学位授予单位中南大学学位授予日期2001 论文页码总数108页关键词隧道工程地质灾害岩爆馆藏号BSLW /2003 /U45 /1 隧道开挖灾害研究必然以地质因素为其主要研究对象。

It consists of the next three aspects: firstly, we study Murthys' open problem whether the augmented matrix is a Q0-matrix for an arbitary square matrix A , provide an affirmable answer to this problem , obtain the augmented matrix of a sufficient matrix is a sufficient matrix and prove the Graves algorithm can be used to solve linear complementarity problem with bisymmetry Po-matrices; Secondly, we study Murthys' conjecture about positive semidefinite matrices and provide some sufficient conditions such that a matrix is a positive semidefinite matrix, we also study Pang's conjecture , obtain two conditions when R0-matrices and Q-matrices are equivelent and some properties about E0 ∩ Q-matrices; Lastly, we give a counterexample to prove Danao's conjecture that if A is a Po-matrix, A ∈ E' A ∈ P1* is false, point out some mistakes of Murthys in [20] , obtain when n = 2 or 3, A ∈ E' A ∈ P1*, i.e.

本文分为三个部分,主要研究了线性互补问题的几个相关的公开问题以及猜想:(1)研究了Murthy等在[2]中提出的公开问题,即对任意的矩阵A,其扩充矩阵是否为Q_0-矩阵,给出了肯定的回答,得到充分矩阵的扩充矩阵是充分矩阵,并讨论了Graves算法,证明了若A是双对称的P_0-矩阵时,LCP可由Graves算法给出;(2)研究了Murthy等在[6]中提出关于半正定矩阵的猜想,给出了半正定矩阵的一些充分条件,并研究了Pang~-猜想,得到了只R_0-矩阵与Q-矩阵的二个等价条件,以及E_0∩Q-矩阵的一些性质;(3)研究了Danao在[25]中提出的Danao猜想,即,若A为P_0-矩阵,则,我们给出了反例证明了此猜想当n≥4时不成立,指出了Murthy等在[20]中的一些错误,得到n=2,3时,即[25]中定理3.2中A∈P_0的条件可以去掉。

The study has focused on: 1 The research background and the current state of the power measurement were analyzed systematically, and then wavelet-based power measurement algorithm was certified feasible for astable signals; 2 We developed a new method of RMS and power measurement based on Dmeyer wavelet. After that three other wavelet measurement approaches were compared with Dmeyer wavelet-based measurement approach. Then the impact on measurement errors of amplitude frequency property and energy leakage of wavelet filter banks were deeply researched, and some measures were proposed to reduce it; 3 We developed a new strategy of power measurement algorithm based on lifting wavelet, which had calculation advantage compared with the first wavelet, so that it was more suitable for the realization of hardware; 4 The running system of wavelet-based power measurement algorithm based on DSP was proposed, and then it was realized on ICETEK-VC5416-A EVM board; 5 Existing problems and the further research direction of wavelet-based power sub-band measurement algorithm was discussed.

本文对基于小波变换的功率测量算法展开深入的分析研究,主要内容有:1)系统地分析了功率分解测量的研究背景、国内外的研究现状,并从能量守恒的角度验证了小波功率分频带测量算法在非平稳信号条件下的可行性;2)首次提出了Dmeyer小波变换有效值与功率的测量方法,进而通过对该方法与3种已经提出的小波测量方法的对比分析,深入研究了小波滤波器组的幅频特性和能量泄漏特性对测量误差的影响,并针对电网谐波的特点提出了减小影响的相关措施;3)首次提出了二代小波功率测量算法,对比一代小波功率分频带测量算法,它大大减少了算法实现的运算量及内存的需求量,从而更适合于硬件的实时实现;4)提出了小波功率分频带测量算法的DSP实现方案,并在ICETEK-VC5416-A EVM板上进行了实现;5)探讨了小波功率分频带测量算法目前仍存在的问题,并提出了进一步的研究方向。

Based on the analysis of the mechanism of robot manipulators, a trajectory tracking controlling research model is first built up with ADAMS, and its mathematical model is formulated through the study of robot kinematics and dynamics. After the modeling errors are analyzed in practical robotic systems, a conception of centralized error is brought forward according to the theory of weighting functions. In the case of modeling errors' exist, the robotic uncertain model is derived by introducing an auxiliary control variable into inverse dynamic analysis. The control strategy of robust exponential convergence is applied to the robotic uncertain model, the applicable conditions and the applicable controller with this application are presented. The stable control effect under three main model uncertainties (parametric errors, joint disturbs, joint frictions) are systematically studied on the previously built research model. The problems of robust exponential convergence controller which often results in unstable output and so produces a large relative error when the input trajectory is in a small range are resolved by adjusting the control parameters based on the controller's structure.

本文在机械手的机械结构分析基础上,利用ADAMS建立了用于机械手轨线跟踪控制研究的机械手模型;通过对机器人运动学和动力学问题的研究,建立了机械手研究的数学模型;分析了机器人系统中模型误差的主要来源,根据加权函数法分析,提出了模型集中误差的概念;在存有模型误差的情况下,采用逆动力学结构并引入辅助控制量,由机器人误差模型推导了机器人非确定性模型;提出了采用鲁棒指数收敛法对上述机器人非确定性模型进行鲁棒镇定的控制策略,并给出了对机器人进行鲁棒指数收敛控制时系统不确定因素应满足的匹配条件;针对机械手研究模型,深入研究了鲁棒指数收敛控制器对机器人系统中常见的模型参数误差、关节扰动、关节摩擦等不确定因素的镇定控制效果;针对鲁棒指数收敛控制器易产生控制量振荡的问题以及在小范围内系统轨线跟踪的稳态误差过大问题,本文分别提出了基于控制器结构的控制参数调整法和基于轨线跟踪范围大小的控制参数分段切换法。

And then compare the different research methods those researchers have taken in their studies, which aims at finding deficiencies and drawing experiences from the past. And basing on that, I point out some research directions in this field.

全文分六部分,内容如下:第一部分介绍了国内外信息界在信息服务价格问题上已取得的研究成果,并对国内外学者在这个问题上的研究方式和方法进行对比分析,目的在于吸取借鉴国内外学者研究过程中的成功经验,发现研究的不足之处,并找到该领域今后的研究方向。

ChapterⅡreviewed the thoughts with utilitarian style of two great thinkers——Bentham and Beccaria, the representatives of classical school of crime. Although their research can not be considered modern economic research, their thoughts contained the essence of economics of crime, and their studies have laid a solid theoretical foundation of modern deterrent theory for the subsequent economic research on deterrence.

本章首先回顾了具有浓厚功利主义风格的两位古典犯罪学派代表人物贝卡里亚和边沁的研究,他们的研究尽管不能被认为是现代经济学的研究,但他们深刻的思想却包含着经济学的很多精髓,而且,他们的研究为后来的犯罪经济学理论研究尤其是威慑理论奠定了坚实的理论基础,也是现代经济学威慑理论的思想源头。

Namely, we should define the equivalence which we can make a comparative study of or a cross-cultural study of on the basis of methodology by building a platform of researching the equivalences of different nations so that we can make the study of national psychology there.

本文从跨文化研究出发,介绍了民族心理学研究的跨文化研究以及研究中的功能等值、概念等值、语言等值以及公制等值四方面等值的确定,以期引起学者们对跨文化研究中研究等值确定的重视。

Gravity wave and ozone are two interesting topics in the middle and upper atmosphere. In this dissertation, they are studied by numerical simulation and instrument development respectively.In section one, by using FICE scheme and TIME-GCM, a model of trace gases and OH airglow affected by gravity wave is set up, then the propagation of nonlinear gravity wave and the effect on trace gases and OH airglow are analyzed. The result shows gravity wave excited by tropospause forcing can propagate stably to the mesosphere through the stratosphere so that energy and momentum can be transferred from one region to another. In this process, gravity wave undergoes growth, overturning, convection and breaking. And the no-isothermal structure can accelerate the breaking of gravity wave in mesospause, and the breaking of gravity wave is an important source of convection and small-scale waves.

中文题名气辉的非线性重力波研究及臭氧总量探测仪的研制副题名外文题名 The study of airglow by nonlinear gravity wave and the development of the total ozone spectrometer 论文作者王咏梅导师刘振兴王英鉴学科专业空间物理学研究领域\研究方向学位级别博士学位授予单位中国科学院空间科学与应用研究中心学位授予日期2003 论文页码总数88页关键词臭氧气辉重力波馆藏号BSLW /2003 /P421 /7 重力波和臭氧是中高层大气中研究的两大热门课题,本文分别从理论模式和仪器研制两方面对它们进行了研究。

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