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The basic pathological change of silicosis is the lung interstitial fibrosis and the formation of silicotic nodule.

矽肺的发病相似,特发性肺纤维化也是以肺成纤维细胞大量增殖为主要特征的肺纤维化疾病。

Methods General and matched follow-up pulmonary function studies lasting for 14 years were performed on 45 retired nickel miners, 37 silicotic patients and 42 control workers.

本文对某镍矿45名退休矿工、37名离尘后定诊矽肺患者和40名对照矿工的肺通气功能进行了14年的追踪与配对追踪观察。

The cell aggregation and cellular nodule were predominant in this group and the collegen increased in these silicotic nodules.

统计 两组中出现5倍量差异的点共有98个,其中,相比正常组,有13个点在IPF组及矽肺组中出现5倍量的增加;而有22个斑点却出现5倍量的减少。

Time constant of pulmonary circulation and mean pressure of pulmonary artery were measured in 21 cases of silicotic emphysema by using improved Simon method.

用改良Simon动脉舒张压力曲线数值拟合法测量21例矽肺肺气肿患者的肺循环时间常数和肺动脉平均压力。

The results indicated that there was lung function loss in the retired miners and the silicotic patients, and the injury of the retired workers seemed to be serious.

长期接触高浓度的矽尘,矿工退休离尘后肺通气功能仍在丧失,损害的严重程度可与矽肺患者相比。

Conclusion]Semen persicae extract inhibited remarkably silicotic fibrosis in rats.

结论]桃仁提取物有延缓矽肺纤维化作用。

GBZ70 - 2002 diagnostic criteria for silicosis and standard chest radiograph for silicotic diagnosis were adopted in diagnosis.

按GBZ70—2002尘肺诊断标准及尘肺诊断标准片阅片,对比观察高仟伏X线胸片与HRCT在矽肺小阴影影像上的差异。

Different content of lung quartz had a direct effect on lung silicotic pathology and the X-ray manifestation of chest, and caused the difference of collagen fibrosis in lung tissue and that in the content of serum ceruloplasmin in individ...

肺石英量的差别导致了个体间肺组织纤维化程度的差异,从而表现为个体间血清铜蓝蛋白含量的差异。研究结果提示,血清铜蓝蛋白含量可作为衡量矽肺病理改变的良好指标之一。

C/EBPβnuclear translocation was observed clearly in the 1-15 days silicotic tissue. There was a significant over-expression of C/EBPβin lung tissue of silica exposed rats as compared with that in the normal ones.

在染尘1-29天(以尘细胞灶和细胞性结节为主)和36-64天(以结节中成纤维细胞明显增生为主)的大鼠矽肺组织中,C/EBPβ表达的程度明显不同,差异有显著性。

The positive expression of TGFβ1, PDGF-B rnRNAs and their proteins were prominent in the proliferative alveolar type Ⅱ cells of experimental group of silicotic models. Weak expression of TGFβ1 mRNA were found only in a part of normal alveolar type Ⅱ cells of control group.

2大鼠矽肺实验组增生的肺泡Ⅱ型细胞明显表达TGFβ1和PDGF-B mRNA和蛋白;对照组仅有部分正常肺泡Ⅱ型细胞TGFβ1 mRNA呈弱阳性。

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