石蒜碱

Obserdose of noradrenaline bitartrate or KCl: Sub-maximal constriction of thoracic aorta was induced by 0.1 mmol/L noradrenaline bitartrate or W60 mmol/L KCl, and when constriction curve became stable, DL or nimodipine of different dosage was added.

记录电刺激心室乳头肌时收缩的幅度变化：1次/s，波宽3 ms，阈电压的120％强度电刺激以引发心室乳头肌同步收缩活动，待收缩曲线平稳后，分别用累加法加入二氢石蒜碱或尼莫地平。

RESULTS: Basilar artery, thoracic aorta and ventricular papillary muscle Resting tension of basilar artery was increased by DL but decreased by niof basilar artery and thoracic aorta induced by noradrenaline bitartrate and KCl can be relaxed by DL in a dose dependant manner, and the half-effective concentration was (6.69±3.12)×10-4,(3.41±1.52)×10-3mmol/L for basilar artery, and (1.49±0.59)×10-3,(2.91±0.99)×10-3 mmol/L for thoracic aorta, displaying stronger inhibition on the constriction of basilar artery induced by noradrenaline bitartrate than on the contraction induced by KCl.

重酒石酸去甲肾上腺素、KCl所致基底动脉及胸主动脉收缩，二氢石蒜碱使之呈剂量依赖性松弛，其半数有效浓度值：对基底动脉分别为(6.69±3.12)×10-，(3.41±1.52)×10-3 mmol/L；对胸主动脉分别为(1.49±0.59)×10-3，(2.91±0.99)×10-3 mmol/L。拮抗重酒石酸去甲肾上腺素所致基底动脉收缩作用明显强于KCl。尼莫地平对KCl所致收缩的抑制显著强于对重酒石酸去甲肾上腺素。

Pharmacological effects research has revealed that lycorine and its derivatives have many pharmacological effects, such as anti-inflammation、antivirus、anti-malarial、 heart-blood system protection and tumor cell killing.

生物活性研究表明，石蒜碱及其衍生物具有抗炎、抗病毒、抗疟疾、抑制乙酰胆碱酯酶、保护心血管以及诱导肿瘤细胞凋亡等多种作用。

An overview of the pharmacological effects of lycorine and its derivatives is given, and advice for further research of lycorine and its derivatives is suggested.

综述了石蒜碱及其衍生物的药理作用研究概况，并就开发石蒜碱及其衍生物提出了建议。

In this manuscript, solvent circumfluence was adopt to Abstract lycorine, homolycorine and galanthamine from Lycoris.

研究了溶剂回流法提取石蒜中的石蒜碱、力可他敏和加兰他敏等生物碱。

Lycorine is a kind of alkaloid constituent which is highly-contained in plant medicine Lycoris radiata.

石蒜碱是传统药用植物石蒜中含量较高的生物碱成分。

The linear ranges of the calibration curves for lycorine,lycoramine and galanthamine were 5.0-400 mg/L,respectively.

采用三乙胺水溶液(pH 9.0)-乙腈-甲醇作为流动相对石蒜碱、力可拉敏和加兰他敏进行HPLC测定，方法的线性范围为5.0~400 mg/L，检出限分别为5.0、5.1、10.2 ng，RSD分别为2.2%、5.7%和4.4%。

The linear ranges of the calibration curves for lycorine, lycoramine and galanthamine were 5.0-400 mg/L, respectively. Their detection limits were 5.0, 5.1 and 10.2 ng, respectively and the RSD were 2.2%, 5.7% and 4.4%, respectively.

采用三乙胺水溶液(pH9.0)-乙腈－甲醇作为流动相对石蒜碱、力可拉敏和加兰他敏进行HPLC测定，方法的线性范围为5.0~400mg/L，检出限分别为5.0、5.1、10.2ng， RSD分别为2.2%、5.7%和4.4%。

Lycorine, lycoramine and galanthamine in Lycoris radiata were microwave-assisted extracted and determined by HPLC using triethylamine aqueous solution (pH9.00)-acetonitrile-methanol as the mobile phase.

采用微波辅助提取法提取石蒜中的石蒜碱、力可拉敏和加兰他敏生物碱，建立了微波辅助提取／HPLC测定石蒜中这3种生物碱的分析方法。

The kinetic mechanisms for the extraction of active constituents in dissimilar plants Lycoris radiata and Rhizma polygoni cuspidati by microwave-assisted extraction were investigated. Lycorine, lycoramine and galanthamine in Lycoris radiate, resveratrol and emodin in Rhizma polygoni cuspidati were target constituents.

以鳞茎药材石蒜和根茎药材虎杖作为研究对象，采用微波辅助提取石蒜中的石蒜碱、力可拉敏和加兰他敏以及虎杖中的大黄素和白藜芦醇，研究了提取过程的动力学机理。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。