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A castration in adults can become necessary because of testicular cancer and other diseases.

因为患睾丸癌和其他疾病,在成年期切除睾丸则是必要的。

Contralateral testicular blood flow of the 8 patients with one testis resected was normal according to color Doppler ultrasonography.

彩超是睾丸扭转首选检查方法,早期诊断、及时手术探查是提高患者睾丸成活率的关键。

At the 7th day after the operation,the contents of NO,MDA in the cryptorchid was significantly higher than in the control,and the level of T-AOC was predominantly lower.

结果术后第7天,与对侧正常睾丸相比,隐睾侧睾丸发生凋亡的生殖细胞数显著增加(P<0.01);T-AOC显著下降;NO和MDA含量显著上升(P<0.01)。

With western blot analysis and DNA polymerase chain reaction-single strand conformation polymorphism assay,protein product of Rb gene and mutation in exon 5~8 of P_(53) gene were examined in 17 cases of human testicular seminoma.

采用Western印迹和DNA聚合酶链反应-单股构造多态性分析法对17例人睾丸精原细胞瘤组织标本的抗癌基因Rb表达的蛋白产物和P_(53)基因外显子5~8的突变进行检测,发现有3例标本的Rb基因表达的蛋白产物缺失,有4例标本的P_(53)基因有点突变,对照的正常人睾丸组织和视网膜组织均呈Rb基因蛋白产物表达阳性,对照的正常人睾丸组织中未发现P_(53)基因突变。

The changes in the weight, exponential, structure of the tissue, cell apoptosis in testis and epididymis and the changes in the sperm tectology in epididymis were measured on the day 8, 13, 21 and 35 of the treatment,respectively,by the method of morphological examination.

分别在热应激持续到8d、13d、21d和35d时,应用形态学观察法,研究受试鼠睾丸和附睾重量及指数、组织结构、细胞凋亡和附睾精子形态学的变化;应用免疫荧光细胞化学和蛋白质印迹分析的方法,研究睾丸和附睾组织中热休克蛋白70(HSP70)的表达;应用比色法检测睾丸和附睾组织内活性氧和丙二醛、抗氧化物酶(SOD、GSH-Px、CAT)的活力或浓度的变化;应用交配试验,检测雄鼠受精能力及其致孕雌鼠的产仔数的变化,用以揭示热应激对雄鼠生殖机能的影响。

Animals, as material, were used to study the toxicity of outer substance and made sure the estrogen effect of BBP by whole animal experiment, and the chronic toxicity of BBP was studied, designed and valued through several dosages and different exposed time. The result showed that BBP could make testis, epididymis and prostate withdrawl. Tectology changes were observed in testis, epididymis and liver. Especially the atrophy and degeneration of seminiferous tubules, decrease of spermatogenic cell and the turbulence of Sertoli cell and spermatogenic cell of seminiferous epithelium were also observed. The linkage between cells vanished.

明确了BBP的雌激素效应,并分别用多剂量和不同染毒时间来研究、设计、评价BBP在体内的慢性毒性,结果表明:BBP能引起雄鼠睾丸、前列腺、附睾性腺的萎缩和肝脏肿大,改变睾丸、前列腺、肝脏的组织形态学,尤其引起睾丸曲细精管萎缩、变性,各级生精细胞减少,生精上皮内生精细胞和Sertoli细胞结构明显紊乱,细胞间连接结构消失等。

In the present paper, the Sox gene expression analysis of different tissues from the Trionyx sinensis was studied by using RTPCR, and Sox gene fragments of expression from the testicle, brain and spleen were cloned using RTPCR products. The results show that Sox gene has specific expression in the testicle, brain, spleen, cardiac muscle and kindney and hasn't expression in muscle, liver and ovary. The results of clone reveal that the Sox genes of expression in the testicle are TSSox1 and TSSox 4, and those are TSSox2 and TSSox4 in the brain, and that is TSSox4 in the spleen. This suggests that the Sox gene act important role not only on the sex determination, but also on the development of neural system, immunocyte system and the differentiattion of male germ cell.

本文采用RT—PCR技术,研究了中华鳖不同组织Sox基因的表达,并通过PCR直接克隆法,分析了来自睾丸、脑和脾组织中的Sox基因序列结果表明在中华鳖的成体组织中,Sox基因在脑、心肌、肾、脾和雄性的睾丸组织中均有不同程度的表达,而在肌肉、肝脏和雌性的卵巢中则无表达,显示该基因具有组织表达特异性克隆分析显示,在睾丸组织中表达的是TSSox1和TSSox4基因,而在脑组织中表达的是TSSox2和TSSox4基因,脾组织中表达的是TSSox4基因此结果表明Sox基因不仅在性别决定中起作用,还可能在神经系统、免疫系统多种组织中起重要作用

These include a decrease in sperm production by almost 50 percent, a three- to four-fold increase in testicular cancer, an increase in the incidence of cryptorchidism (undescended testes, a condition where the testes are not in their normal location in the scrotum) and hypospadias.

这些还包括:精子产生量下降大约50%,三倍到四倍的睾丸癌发病率,隐睾症发病率增高(没有下降的睾丸,睾丸没有在阴囊中的情况)、尿道下裂。

Results:weijian obviously shortened the latent period of erection in castrational rats after electric stimulus and the latent period of coitus in castrational mice,increased coitus times in castrational mice,increased the appearance rate of sperm suppository in copulated female mice. the acute toxicity tests showed that the half lethal dose(ld50) of weijian was 901.53 mg/kg and 319.60 mg/kg, the long-term toxicity tests showed that large dose of weijian slightly increased the level of glutamic pyruvic transaminase and decreased the glucose,triglyceride and cholesterol of blood, while had no effects on other biochemical factors.

结果: 伟剑能明显缩短去睾丸大鼠的电刺激阴茎勃起潜伏期,明显缩短去睾丸小鼠的性交潜伏期,并增加去睾丸小鼠的性交次数,增加交配后雌性小鼠的精栓出现率;急性毒性试验测得伟剑的口服半数致死量(ld50)为901.53 mg/kg,腹腔注射的ld50为319.60 mg/kg;长期毒性试验研究表明该药在大剂量时可轻度升高谷丙转氨酶,轻度降低血糖、总胆红素及胆固醇,而对其他血液生化指标无影响。

Methods Bilateral spermatic veins and testis volume of 73 men with varicocele and 30 normal men were detected by Color Doppler Ultrasound,and analysed about the correlation between the spermatic vein diameter and testis volume,and the correlation of the bilateral spermatic veins;the volume change of left testis and diameter change of left spermatic vein of 23 men in the case were retrospectively analysed.

采用彩色多普勒超声对30例正常人及73例精索静脉曲张患者的双侧精索静脉及睾丸体积进行检测,分析双侧精索静脉内径之间、患侧精索静脉内径与睾丸体积之间的相关性;回顾分析其中23例患者左侧精索静脉内径及左侧睾丸体积的变化。

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