睾丸的

Results showed that TDI induced toxic action on spermatogenic cell,while the chondriosome was its target within the length and concentrations.

结果表明：在本实验染毒时间和染毒剂量范围内，TD I对雄性的生殖毒性主要表现为对各级生精细胞均有一定的毒性作用，作用的靶点是细胞内的线粒体；TD I通过影响各种酶的活性，干扰了睾丸组织的有氧代谢和无氧供能，抑制了细胞对能量的利用，损伤了各级生精细胞，导致生精上皮不可逆的损害，从而造成了其对雄性生殖系统的损伤；TD I对雄性生殖细胞的核酸代谢以及DNA合成有一定影响。

They existed as dosage-effect and time-effect. All of these results proved that Sertoli cell was the first target cell, spermatogenic cell was the second one and mitochondrion was the target. Otherwise, we proved this compound can disturb the development and growth of sperms, influence the activity and amount of sperms and increase the deformation ratio.

结合组织病理和性激素及酶活性的改变，揭示该化合物睾丸毒性的靶细胞是支持细胞，其次是生精细胞，作用的靶点是细胞内的线粒体，此外还证明该化合物干扰精子的生长和发育，影响精子的活力和数目，增加畸形率，是雄性精子畸变的诱导剂。

Peripheral plasma membrane proteins extracted from the spermatozoa from caput,corpus and cauda epididymis as well as vas deferens were probed with four lectins—Arachis hypogaea agglutinin、Canavalia ensiformis agglutinin、Dolichos biflorus agglutinin、Triticum vulgaris agglutinin.The results indicated that the 104 and 95kD AHA binding glycoproteins,and the 117、114、104、87、76、70kD ConA binding glycoproteins were synthesized and modified in the testis;the 120 and 65kD ConA binding glycoproteins,and the 54kD DBA binding glycoprotein were modified or lost during epididymal maturation;the 109kD ConA binding glycoprotein,the 74、70、45kD DBA binding glycoproteins,and the 57kD TVA binding glycoprotein were modified during epididymal maturation.

结果表明：与花生凝集素结合的104kD和95kD糖蛋白，与伴刀豆凝集素结合的117、114、104、87、76、70kD糖蛋白在睾丸中已完成了蛋白合成及修饰过程；与伴刀豆凝集素结合的120kD和65kD糖蛋白，与双花扁豆凝集素结合的54kD糖蛋白在精子附睾成熟过程中被修饰成其它种类的蛋白或被丢失；与伴刀豆凝集素结合的109kD糖蛋白，与双花扁豆凝集素结合的74、70、45kD糖蛋白，以及与麦胚凝集素结合的57kD糖蛋白是在附睾中完成其修饰过程的。

The females incubated at 33 , their ovarium has powerful cortex, the germinal epithlium produce oocyte, its medulla degenerate into ovarian cavity. During sexual differentiation, mitochondria and smooth endoplasmic reticulum in cells of ovary increase in quantity, they disintegrate after sexual differentiation. There are a lot of big grana in cells of ovary before sexual differentiation, in the course of sexual differentiation the quantity of the big grana decrease, while small grana increase and peakafter sexual differentiation. The males incubation at 26 , cortices of their testes degenerate into a thin albuginea. Medulla are formed by testicular cords in which scatter spermatogonium.

33℃下孵化的小龟卵巢皮质发达，由原始生殖细胞产生卵原细胞，髓质退化成为卵巢腔，分化时卵巢细胞的超微结构显示线粒体和内质网的数量大大增加，它们在分化结束后解体，分化前细胞内有较多的大颗粒，在分化中大颗粒减少，小颗粒增多，在分化后小颗粒达到最多。26℃下孵化的小龟精巢皮质退化成为一层薄的白膜，髓质有许多睾丸管构成，管腔内有散落排列的精原细胞。

Results:Expression of elastase mRNA has been found in the endothelial cells,the medial smooth muscle cells and the adventitial fibroblasts of the abdominal aorta,the lymphocytes,monocytes in blood,the tracheal hyaline cartilaginous cells,the glandular cells of the pancreas,the epithelial cells of the parotid gland and submaxillary gland,the hepatoeytes,the endothelial cells of the liver sinusoid wall,the goblet cells of the mucous membrane of the small intestine,the cardiac myocytes,the renal interstitial fibroblasts,the alveolar epithelial cells,the cerebral glial cells,the fibroblasts of the dermis oorium of the skin,the primary spermaocytes,the secondary spermaocytes and sperm in the seminfferous tubule of the testis,the lymphocytes in the spleen and thymus.

结果正常大鼠腹主动脉的内皮细胞、中膜平滑肌细胞以及血管外膜成纤维细胞，血液细胞中的淋巴细胞、单核细胞，气管透明软骨细胞，胰腺的腺细胞、腮腺、颔下腺上皮细胞，肝细胞、肝窦壁的内皮细胞，小肠黏膜杯状细胞，心肌细胞，肾间质的纤维母细胞，肺泡上皮细胞，大脑胶质细胞，皮肤真皮纤维母细胞，睾丸曲精细管内的初级精母细胞、次级精母细胞以及精子，脾脏以及胸腺的淋巴细胞等，均有弹力蛋白酶mRNA的表达。

To reseach the mechanisms of ED wtih DM from the acpects of endocrinology, morphology and molecular biology, using rats from NDM and STZ groups as control, the concentration of testosterone, LH and FSH in sera, the microstructure of testicular tissue, bulbocavernous and ischiocavernous muscle tissue, and penile cavernous tissue, the ultrastructure of penile cavernous tissue, and the expression of nNOS mRNA, the content of nNOS and eNOS, the activity of NOS and the concentration of cGMP in the pathway of LARG-NO-cGMP in penile cavernous tissue from ED rats with DM were reseached or examinated in Group A, B and C.

本实验利用第一部分所建立的DM性ED模型，采用NDM及STZ大鼠作对照，通过对A组、B组及C组DM性ED大鼠血清中睾酮、LH及FSH浓度的测定，睾丸组织形态结构的研究从内分泌方面探讨DM性ED的发病机理；通过对阴茎海绵体组织显微及超微结构和球海绵体肌及坐骨耻骨肌显微结构的研究，首次从形态学方面探讨DM性ED的发病机理；通过对阴茎海绵体组织L-ARG-NO-cGMP通路中nNOS mRNA表达、nNOS及eNOS含量、NOS活性及cGMP浓度的检测，从分子生物学方面探讨DM性ED的发病机理。

The results indicated that (1) the 147Pm, 141Ce and 147Nd had strong adsorptivity in soil, so they were hard to transfer and easily accumulated in soil or sediment;(2) all the organisms (5 aquaties and 4 eatable plants) tested showed apparent 147Pm concentrating capabilities;(3)the residues of 147Pm, 141Ce and 147Nd were unevenly distributed in the animal's viscera and tissues, higher residues were found in bone, marrow, eye, brain, heart, adipose and testis, showing selective accumulation;(4) with intraperitioneal dosing of Nd or Ce 200mg ·kg -1 apparent inhibition to gonadial hormone secretion in mice was found and with 200 and 800mg·-1 of Ce added in feed, the malformation rate of spematozoon showed higher.

综合研究结果表明： 14 7Pm、14 1Ce和14 7Nd在土壤中具有强的吸附性，而且难以迁移，易于在土壤和底泥中积累；( 2 )供试的 5种水生生物、4种陆生食用植物对14 7Pm均具有明显的富集性；( 3) 14 7Pm、14 1Ce、14 7Nd在动物体内脏器和组织间呈不均匀分布，在骨骼、骨髓、眼、大脑、心脏、脂肪和睾丸中残留量较高，表现了明显的选择性蓄积；( 4 )一次性腹腔注射2 0 0mg·kg-1的Ce和Nd对小鼠性腺激素的分泌有明显的抑制作用，以 2 0 0和80 0mg·-1的Ce随饲料摄入对雄性小鼠精子畸形率明显升高。

With stimulation of the high-speed spiral massage on the relative reflexive areas(for example,gonad,pituitary gland,adrenal gland,testicle, prostate gland,ovary and the like),the endocrine system will promote the secretion of gonadotrophin,uch as testosterone and oestradiol.

通过对应的反射区的高速螺旋循环刺激，如对生殖腺、脑垂体、肾上腺、睾丸、前列腺、卵巢等反射区的刺激，可增加人体内分泌系统中的性腺激素如：睾酮、雌二醇的分泌量，对男性前列腺炎、肥大及男、女功能障碍（阳痿、早泄、阴道干涩、无高潮、性冷淡等）均有一定程度的改善，进而可提高夫妻性生活质量、维持家庭的和谐幸福。

To study the effects on the body of animals after incorporation of 3H-TdR and its mechanism, the laws of distribution A retention and absorbed dose in blood , thymus, spleen, femur, heart, lung,kidney, liver, brain , spermary , small intestine and muscle were detected by liquid scintillation counter after 3H-TdR was injected into the tail vein of mouse; the process of dynamic incorporation of in the lymphocytic cell nucleus of blood , thymus , spleen and the nucleus of femur was monitored; the absorbed dose in the cell nucleus was estimated; the influence to RNA"s synthesizing and cell"s survival was observed using the technology of CLSM; A segment of Egr-1 gene was cloned with reverse transcriptase- polymerase chained reaction, the influence to the expression of Egr-1 gene in the spleen cells was observed.

为了探讨有机结合氚内污染对生物机体的影响及其作用机理，本课题应用均相液体闪烁测量技术研究了氚标记胸腺嘧啶核苷(~3H-TdR)经尾静脉注入小鼠机体后，在血液、脑、胸腺、心脏、肺脏、肝脏、脾脏、肾脏、小肠、睾丸、肌肉和股骨共12种组织器官的生物动力学分布规律及其吸收剂量；应用纸片法液体闪烁测量技术研究了~3H-TdR内污染在外周血、胸腺和脾脏淋巴细胞及骨髓细胞的动态滞留规律，估算了细胞核的吸收剂量；应用共聚焦显微镜观察了~3H-TdR内污染对脾细胞核酸合成及其存活率的作用，应用反转录PCR技术研究了~3H-TdR内污染对脾细胞早期生长反应基因-1(Egr-1)转录表达的影响。

Meanwhile, Lubo Penev, the star of the team, was diagnosed with cancer of the testicles that kept him one year away from football, but from which he fortunately recovered completely. A very young Gaizka Mendieta started to play his first matches as well. He had signed up coming from Castellón and has become the big star of the present Valencia. Another personal tragedy happened in Valencia in September of 1993: the Panamanian forward Rommel Fernández, on loan to Albacete, was killed in a car accident.

在这个时候，队中球星Lubo Penev被诊断出患有睾丸癌而离开足球一年，幸运的是在这段时间里他获得了痊愈。aizka Mendieta，一位非常年轻的运动员开始了他的第一场比赛，他是从Castellón签过来的，后来成了瓦伦西亚队的巨星。1993年九月，另一个个人悲剧降临到瓦伦西亚：被租借到阿尔巴塞特队的巴拿马前锋Rommel Fernández在一场车祸中丧生。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。