睾丸的

It is a complex process involving cell division, differentiation and interaction between cells in the microenvironment of the seminiferous tubule.

睾丸生精小管中的生精细胞先后经过三个阶段的变化：精原细胞的增殖，精母细胞的减数分裂和精子细胞的变态过程，最终产生成熟的精子。

Using the Hprt gene as a positive control, our result suggested that both the testis tissue and the male embryos from which Sry transcription can be detected failed to yield any positive results of Xist. Female embryos at the pronucleus stage and 2-cell failed to produce any positive result of Sry and Xist too.

然后利用实验一确定的PCR条件，以Hprt为阳性对照，用巢式RT-PCR对小鼠早期胚胎进行Xist基因的转录分析，结果发现，转录Sry基因的睾丸组织以及雄性胚胎，从受精卵发育到囊胚的过程中，基本上不转录Xist基因；不转录Sry基因的雌性卵母细胞和雌性胚胎，从出现原核开始，到发育至2-细胞期的过程中，Xist基因一直不转录，但是，从4-细胞期开始，一直到孵化前囊胚阶段，雌性胚胎都转录Xist基因。

In mammals, testosterone synthesized by testis interstitial tissue play an important role in the physiological procedures such as malization of embryo development, production of sperm, male sexual behavior and male sex gland development.

在哺乳动物中，睾丸间质组织合成分泌的睾酮在胚胎发育的雄性化、精子的生成、雄性性行为以及雄性性腺的发育等生理过程中起着重要的作用。

Studies have linked the phthalates or their metabolites, including monoethyl phthalate and mono-n-butyl phthalate, with androgen-lowering activities, abnormal Leydig cell function, a decrease in anogenital distance in male infants, and reproductive tract malformations including hypospadias.

研究联系在一起的邻苯二甲酸盐或其代谢物，包括monoethyl苯二甲酸的和单丁酯邻苯二甲酸，与雄激素降低的活动，不正常的睾丸间质细胞功能，减少肛门生殖器距离的男性婴儿，生殖道畸形包括尿道下裂。

P-gp is expressed in normal biliary canaliculi of the liver, the adrenal cortex and proximal tubules of the kidney, and intestinal epithelia including the columnar cells of the large and small intestines; capillary endothelial cells of brain, testis, and placenta; and in the hematopoietic stem cells of bone marrow.

P-gp表达于正常的肝脏胆小管，肾脏的，肾上腺皮质和近端小管，以及包括大肠和小肠的柱状细胞在内的肠上皮细胞；脑、睾丸和胎盘的毛细血管内皮细胞；以及骨髓的造血干细胞。

But a piece of research just published in the Proceedings of the National Academy of Sciences by Paola Sapienza of Northwestern University, near Chicago, suggests an alternative—that it is not a person's sex, per se, that is the basis for discrimination, but the level of his or her testosterone.

但是靠近芝加哥的西北大学圣保罗分校最近在国家科学院的报告中发布的一些研究让人们对此看法有所改变——人们对一个人的性别并不是基于偏见，而是取决于他睾丸激素分泌的程度。

Well, it might. But a piece of research just published in the Proceedings of the National Academy of Sciences by Paola Sapienza of Northwestern University, near Chicago, suggests an alternative—that it is not a person's sex, per se, that is the basis for discrimination, but the level of his or her testosterone.

嗯，可能吧。但是由芝加哥附近的西北大学Paola Sapienza研究组在美国科学学院报上刚刚发表的一份研究却给了另一个可能的答案，就是歧视的根源不在于本身的性别而是他或她的睾丸素水平。

The results of flow cytometry in normal, B27 single transgenic mice and B27/hβ〓m double transgenic mice were 0.63％, 7. 87％ and 35. 87％ respectively. B27 antigen was also expressed in the cell surface and cytoplasm of colon, skin, testis and eyes of the double transgenic mice by the detection of immunohistochemistry, which was evident on the cell surface. 8 double transgenic mice bearing high copy (7 males, 1 female) developed spontaneous alopecia, psoriasiform dermatosis, joint swelling and nail changes in the rear paw.

免疫组化检测可见转基因小鼠的结肠、皮肤、睾丸和眼睛组织的细胞膜和细胞浆均有B27抗原的存在，尤以细胞膜明显。21只B27/h〓转基因阳性鼠中有8只出现脱毛和皮肤的银屑病样改变，同时伴有后肢的关节肿胀和趾甲变化。8只小鼠均为高拷贝，其中雄性7只，雌性1只。

The sensitive level is different between different day-age Jimpy mice. To induce the BPH model with the 60-70 day-age Jimpy mice, should take the hypodermic Adm-way or add dosage in intragastrica Adm-way.

不同日龄的小鼠对丙酸睾丸酮的敏感程度不同，对60~70日龄的小鼠前列腺增生造模宜采用皮下注射的给药方式或加大灌胃的剂量。

Objective: The aims of our research are ① to filter candidate Wnt genes which are important for maintenance of normal hESCs or resulting in karyotypic change through analysis of Wnt genes of differential expression in human and mouse feeder cells and hESCs during culture of normal or abnormal karyotype hESCs.② to research the function of Wnt9a that RNAi for human Wnt9a were performed.

研究目的：对核型正常和异常的人类胚胎干细胞在体外培养过程中Wnt基因在饲养层和hESCs中的差异表达分析，分别筛选出可能促进hESCs正常增殖和引起核型发生变化的候选Wnt基因，并对其中的Wntga候选基因进行RNAi研究，了解其生理功能；在小鼠睾丸或生殖域中克隆与生精相关的新基因，并对其功能进行初步研究。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。