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Due to the deficiency of cyclin B1 and 〓, spermatogonia and pachytene/diplotene primary spermatocytes in contralateral cryptorchid testis were unable to form MPF, and therefore, they could not accomplish their nuclear division, and became arrested at the transition stage from mitosis to meiosis (G2/M phase). We also found that testosterone could regulate the cyclin B1 expression in spermatogenic cells.

由于cyclin B1和〓的缺失,粗线期/双线期初级精母细胞中的MPF无望形成,从而导致生精细胞分裂停滞在由有丝分裂向减数分裂过渡的G2/M相;(5)睾酮可在翻译水平上调控阴囊内睾丸生精细胞cyclin B1蛋白的表达。

Excessive intra-abdominal temperature is not conducive to sperm production, testicular malignant risk also increased significantly.

腹腔内过高的温度不利于精子的产生,睾丸恶变风险也大大增加。

Within 3 weeks, their ovaries were full of tubelike structures usually found in testicle tissue.

在3周的时间里,它们的卵巢内充满了管状结构,这种结构通常在睾丸组织中才能找到。

Of the 5 patients with available follow-up, 3 were free of disease at 1, 5, and 8 years after orchiectomy (2 necrotic seminomas and 1 germ cell tumor, unclassified). One patient with yolk sac tumor (age 63 y) developed widespread metastases after 15 months and died of disease.

随访了5例患者,其中3例于睾丸肿瘤切除术后1、5和8年任健在且无复发(2例为坏死的精原细胞瘤、1例为未分类的生殖细胞肿瘤)。1例为内胚窦瘤(63岁),15个月后广泛转移,并死于本病。

Boys born with undescended testicles are 60 percent more likely than other boys to be infertile when they grow up. Furthermore, the researchers beliee that poor testicular deelopment in the uterus may lead to later fertility problems een in boys who don't show the genital abnormality at birth.

伴有阴睾的男孩长大后比其他男性多60%可能性患不育症,还发现,在母体子宫内双侧睾丸发育不良的男性会导致长大后不育,即使他们出生时无外生殖器异常。

During the first two weeks after birth, the growth performances were not significant between the mutant mice and the normal ones, but after that, the mutant mice grew much slower. The differences were significant in the indexes of eyes, lungs, thymuses, and adrenal glands between the genders. At the same time, the differences were significant in the organ indexes, such as lungs, adrenal glands, uterine and testicles between the normal phenotype mutant mice and the abnormal ones. And these two kinds of mice showed different amount of hemoglobin and red blood cell.

结果:B6-Co小鼠不育率22%、平均产仔数5.62±2.55只、离乳成活率56.59±41.22显著低于正常的B6小鼠,而胎间隔29.50±10.50天比正常B6小鼠短。B6-Co小鼠出生后2周内生长发育与正常B6小鼠基本一致,2周后,其生长发育慢于正常B6小鼠。B6-Co小鼠雌雄间的眼球、肺、胸腺、肾上腺的脏器指数差异有统计学意义。B6-Co表型异常小鼠与B6-Co表型正常小鼠相比,肺、肾上腺、子宫、睾丸的脏器系数差异有统计学意义。B6-Co小鼠表型异常小鼠在血红蛋白和红细胞数量上异于B6-Co表型正常小鼠。

Results: B6-Co mice showed higher sterile rate, and significant lower average litter size and survival rate at weaning than the normal B6 mice, but the time interval between deliveries was shorter in the mutant population. During the first two weeks after birth, the growth performances were not significant between the mutant mice and the normal ones, but after that, the mutant mice grew much slower. The differences were significant in the indexes of eyes, lungs, thymuses, and adrenal glands between the genders. At the same time, the differences were significant in the organ indexes, such as lungs, adrenal glands, uterine and testicles between the normal phenotype mutant mice and the abnormal ones. And these two kinds of mice showed different amount of hemoglobin and red blood cell.

结果:B6-Co小鼠不育率22%、平均产仔数5.62±2.55只、离乳成活率56.59±41.22显著低于正常的B6小鼠,而胎间隔29.50±10.50天比正常B6小鼠短。B6-Co小鼠出生后2周内生长发育与正常B6小鼠基本一致,2周后,其生长发育慢于正常B6小鼠。B6-Co小鼠雌雄间的眼球、肺、胸腺、肾上腺的脏器指数差异有统计学意义。B6-Co表型异常小鼠与B6-Co表型正常小鼠相比,肺、肾上腺、子宫、睾丸的脏器系数差异有统计学意义。B6-Co小鼠表型异常小鼠在血红蛋白和红细胞数量上异于B6-Co表型正常小鼠。

Results Following orchiectomy 7d,the amount of CGRP-immunoreactive nerve fibers in the AP of the rat increased significantly, with the tortuous varicose fibers more densely distributed than that of NOR and the amount of varicosities increased significantly, while the thick fibers were more thicker than that of NOR,and many thin fibers were sent out from the thick fibers, and the varicosities were more larger.

结果 睾丸摘除7d后,大鼠垂体前叶CGRP免疫反应神经纤维发生了显著变化,表现为膨体型纤维较正常组稠密,分支增多,迂曲成片,盘绕成网,分布更加广泛,膨体数量显著增多;粗纤维较正常组粗,且发出许多迂曲盘绕的细纤维,膨体形态变大。t检验显示,OX组与NOR组垂体前叶内CGRP免疫反应神经纤维的平均面积密度差异显著,OX+V与NOR组差异显著。

Methods: The testis were observed and the spermatic venous plexus were traced 5cm superior to the deep inguinal ring. The vein's origin, composition, branches and distribution were observed and its diameter were measured.

解剖25具正常成人男尸两侧精索静脉,自睾丸向上追踪蔓状静脉至内环上方,观察静脉的走行及属支,并测量其直径。

The reason men get hernias is the spermatic cord has to come from the testicles into the body and then come back out through the penis.

男人得疝气的原因是,精索必须经由睾丸进入体内,然后再回到阴茎内。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。