着丝粒

This may be the performance of the feedback regulation to the drug inducing function to cell cycle checkpoints, and the gene expression regulation of CenpB, an important centromere constitutive protein, may be related to it distinctly.

这可能是细胞周期检验点应对药物诱导作用的反馈调节的体现，而重要着丝粒结构蛋白CenpB蛋白的基因表达调节与之可能有明显的相关性。

To accomplish this, sister chromatids must segregate together during the first meiotic division , which requires that sister chromatid cohesion persists at centromeres.

实现减数分裂，姐妹染色体必须在第一次分裂联会，这过程姐妹染色体在着丝粒结合。

When Tetrahymena, Euglena, Crypthecodinium and Oxyrrhis were stained with the same technique, although all the nuclei gave positive reactions, no precentromeres could be distinguished; within nuclei there were only patches composed of minute fluorescent spots seen.

在对小眼虫和寇氏隐甲藻作制备核骨架的细胞分级抽提处理后，细胞核仍还都呈阳性反应。这表明与高等真核生物的相似，低等真核生物的着丝粒蛋白也是与核骨架紧密结合的。

This experiment works on:1.prepare marrow cell chromosome samples;2.take pictures of chromosome in karyon by lens-check;3.Measure the length of chromosome short arm and long arm,calculate the relative length of frog chromosome and the arm index and the position of centromere,with the leven method of outside-body karyon pattern analysis.

本实验制备了骨髓细胞的染色体标本，并且通过镜检拍下一个细胞核中染色体的照片，用leven方法进行体外核型分析，测量每条染色体的长臂长与短臂长，并计算出青蛙染色体的相对长度，臂指数和着丝粒。

The percentage distance (from the hybridization sites to centromeres) was(51.79±1.24)%.P5CS is widely present in monocot and dicot.

该探针定位于水稻第9染色体的短臂近端点处，信号点距着丝粒的相对距离为(51.79±1.24)%。P5CS基因广泛存在于单子叶和双子叶植物中。

Methods Lymphocytes were obtained from healthy donors of different ages, both sexes, and were treated with cytochalasin B. Binucleated cells were hybridized with chromosome 21 specific probe, and simultaneously, chromosome 21 loss and nondisjunction were detected.

用细胞松弛素B处理不同年龄及性别正常人外周血淋巴细胞获得的双核细胞，以21号染色体近着丝粒特异性探针进行荧光原位杂交，同时检测21号染色体丢失及不分离。

They affect the development of organismal characters such as sex determination,the functional determination of centromeres,the development of Drasophila's eys,the prion pathogenicity and cancer formation greatly.

它对生物体的性状发育如性别决定、着丝粒的功能决定、果蝇复眼发育、朊病毒致病性的获得及癌的发生等等方面有着重要的影响。

The spiny eel , belonging to Perciformes, Osteichthyes, is a kind of little freshwater fish distributed in Southern China. In 1998, Our lab detected XX/XY differentiated sex chromosomes in this specie with karyotypic analysis, and then with chromosomal binding and SC observation, we identified that its two largest metacentric chromosomes were X, Y sex chromosomes in 1999. X, Y chromosomes differ each other not only in the distribution of heterochromatin but also in their shapes, which make them could be recognized directly under the light-microscope without any banding treatment.

刺鳅，属鲈形目、刺鳅科(Perciformes，Mastacembelidae)，是广泛分布于中国南方的小型淡水鱼类。1998年，我室通过核型分析，首次发现该物种具有明显分化的异形性染色体，其性别决定类型为XX／XY型。1999年，本室通过染色体显带、精母细胞联会复合体观察，再次确认刺鳅染色体组中最大的一对中部着丝粒染色体为X、Y性染色体，两者不仅已经出现结构异染色质分布上的不同，同时在外部形态上也存在明显差异，识别特征鲜明，在光镜观察下无需显带即能清晰辨认性染色体。

Formation of SCs starts at zygotene and completes at pachytene.

在粗线期可见28条清晰的SC，在各SC均未见有相当于着丝粒区域的分化结构。

Results Stable Spectral Karytyping method was set up and extraordinary multiplicity of structure, including metathesis、depletion、amplification、rearrangement、equiarm、marker-body and so on were found by this methad.

结果 我们建立了稳定的光谱核型分析方法，发现肿瘤实体瘤染色体异常呈多倍体且结构异常复杂，包括易位、缺失、扩增、重排、双着丝粒、等臂及标记染色体等。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。