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Research background: Choroidal neovascularization is a common cause of vision loss in patients, which often resulted from exudative Age-related macular degeneration、 pathologic myopia、 central serous chorioretinopathy、ocular histoplasmosis and angioid streaks, Rarely, CNV is seen in children, usually in association with inherited macular dystrophies. Despite extensive basic and clinical research, our knowledge of the complicated molecular mechanism of CNV is still limited, for these reasons currently used therapeutic approaches are insufficiently effective.

课题研究背景:脉络膜新生血管(choroidal neovascularization,CNV)是导致视力丧失的一种常见原因,多继发于渗出型年龄相关性黄斑变性、近视性黄斑变性、中心性浆液性脉络膜视网膜炎、眼组织胞浆菌病和眼底血管样条纹等眼病,在儿童罕见,主要与遗传性黄斑营养不良有关,尽管近年来进行了大量的基础和临床研究,但对CNV复杂分子机制的认识仍然非常有限,因此目前的治疗措施都不尽如人意。

AbstractLacrimal duct obstruction disease is a common disease in Ophthalmology, its incidence increases these years, its main symptom is epiphora, and it can cause acute or chronic dacryocystitis, and become a potential source of infection in eye, so the treatment of this disease is a hot issue in Ophthalmology.

泪道阻塞疾病是眼科中的常见病,近年来发病率一直呈上升趋势,其主要症状是溢泪,治疗不及时还可能引起急慢性泪囊炎,成为眼部潜在的感染源,因此该病的治疗一直是眼科的热点问题。

The majority of eye disease Beheet performance anterior uveitis necrotizing retinal vascular disease is also common, and hyphema Beheet concentration is a feature of eye disease.

Behcet病大多数的眼部表现是前部葡萄膜炎视网膜的坏死性血管病变亦常见,而前房积脓是Behcet病眼部的一个特征。

Intravitreous injection with combination of vancomycin and aminoglycoside antibiotic is widely used for the treatment of endophthalmitis. Unfortunately, macular infarction was reported as a toxic sequela of aminoglycosides, including gentamicin as well as amikacin which was previously thought to be safe.

感染性眼内炎最常使用的治疗方式之一是经由玻璃体内注射抗生素,目前普遍使用的是 vancomycin加上aminoglycoside,但是,aminoglycoside对视网膜具有毒性,甚至有文献报告产生黄斑部坏死的病例。

In this study,we investigate the efficacy and safety of intraocular use of fluconazole in the treatment of ocular fungal infection. Ten patients with intraocular fungal infections were examined. Among these patients , eight were infected with keratomycosis with intraocular spreading, one had postoperative fungal endophthalmitis after cataract operation with an intraocular lens implant, and another suffered from endogenous fungal endophthalmitis.

为探讨眼球内注射fluconazole用於治疗眼球内霉菌感染之效果以及安全性;我们搜集十位眼球内霉菌感染的病人,其中包括八位严重角膜霉菌感染;两位为霉性眼内炎,这些病人在传统治疗无法有效控制感染后,都曾接受眼球内注射fluconazole的治疗,包括前房灌洗、前房内注射或玻璃体内注射,使用浓度为5-10g/ml。

In Stevens Johnson syndrome the mucosal shedding in the tracheobronchial tree may lead to respiratory failure and ocular sequelae which may include anterior uveitis and corneal ulceration, with blindness that may develop secondary to severe keratitis or panophthalmitis in 3 to 10 percent of patients.

在史蒂文斯强森症候群粘膜脱落,在气管,支气管树可能会导致呼吸衰竭和眼的后遗症,其中可能包括前葡萄膜炎及角膜溃疡,失明的可能发展中严重的角膜炎或panophthalmitis在3至10 %的病人。

Methods Separating the posterior synechia with the help of viscoelastics.36 eyes of 32 patients were extract by means of non cuting pupil dilation,excision of the organized membranes of pupilary occlusion and seclusion.

借助粘弹剂分离虹膜后粘连,并采用非切开的瞳孔扩张成型术及膜闭切除术,对32例( 36眼)伴有虹膜后粘连且瞳孔不能放大的葡萄膜炎并发性白内障,行囊外摘出联合人工晶状体植入手术。

Prompt systemic megadose corticosteroid treatment is effective in the treatment of bilateral optic neuritis following HZO.

眼部带状庖疹后的迟发性双眼视神经炎之可能是起源於免疫调控之发炎反应,所以及时的全身性类固醇治疗可以阻止视神经损伤,进而恢复视力。

The traumatic endophthalmitis result from wax bacillus become had rapidly, and often destroys the eyeball in 24 hours, the vitreous body excision with antibiotic application is the treatment effective method, but the prognosis is not good.

蜡样芽胞杆菌所致外伤性眼内炎发病迅速,常在24小时内破坏眼球,玻璃体切除联合抗生素的应用是治疗的有效方法,但预后不佳。

Some symptoms of uveitis would include one or any combination of the following: squinting, sensitivity to light, third eyelid protrusion, tearing, redness to the white part of the eye, abnormal pupil shape or size, or an altered, muddy or reddened iris color.

一些症状葡萄膜炎将包括一个或任意组合如下:眯眼,敏感性轻,第三眼睑突出,撕裂,发红的白色部分的眼睛,异常瞳孔形状或大小,或改变,泥泞或虹膜颜色变红。

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