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Objective To compare the anterior aqueous humor levels of ofloxacin and tobramycin following topical ocular administered in rabbits.

眼内炎的预防和治疗一直是人们比较关心的问题,寻找一种安全、有效的药物是解决问题的关键之一[1]。

Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome

目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析,并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography,FFA)、吲哚青绿血管造影(indocyanine green angiography,ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例,73.5%),双眼同时患病118例(80.8%);后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%);前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例,98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%);后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障;毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现;炎症活动期FFA典型表现为斑驳状高荧光,ICGA发现脉络膜血管扩张、通透性增高等改变;VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎,随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。

RESULTS: Rapidly progressive crystalline lens opacification occurred in 9 eyes within 4 to 15 weeks after diagnosis of Acanthamoeba keratitis. Three were associated with inflammatory complications, including anterior scleritis (2 eyes) and iridocyclitis (1 eye).

结果:在诊断为棘阿米巴角膜炎后,9只眼在4-15周内迅速发生了晶状体的混浊。3只眼与炎性并发症相关,包括前巩膜炎(2只眼)和虹膜睫状体炎(1只眼)。

2 Treatment method is less than a month treat a little patient to use method of massage drop medicine first, treat 1~2 week, 2~3min is massaged before daily drop medicine, be more than the little patient of a month, if drop medicine treats 1~2 week to did not see,improve to still have apparently weep the person that reach secretion, applied medicaments pressurization rinses lachrymal path, use pinhead of vein of skin of tube head of nylon of self-restrained and different type to grind blunt, make rinse a needle continuously, groovy operation, after syringe needle inserts lachrymal canaliculus, nylon the canal is secured with adhesive plaster at the head, undertake rinsing, 1 / D, with oxygen fluorine to lotion Sha Xing adds loose diluent of rice of ground a place of strategic importance, pressurization rinses 3~4 second, invalid still, undertake probing of groovy tear path is operated.

我科自2000年1月至2006年12月,共治疗新生儿泪囊炎178例、230眼,疗效满足,报告分析如下。1资料和方法1.1一般资料新生儿泪囊炎患儿168例、230眼,男102例,女66例,年龄:2d~3个月,均为本院眼科门诊确诊的新生儿泪囊炎患儿。1.2治疗方法小于1个月的首次就治患儿采用按摩滴药法,治疗1~2周,每日滴药前按摩2~3min,大于1个月的患儿,如滴药治疗1~2周未见明显好转仍有流泪及分泌物者,应用药物加压冲洗泪道,采用自制不同型号尼龙管头皮静脉针头磨钝,制成直的冲洗针,常规操作,针头插入泪小管后,将尼龙管用胶布固定于头部,进行冲洗,1次/d,冲洗液用氧氟沙星加地塞米松稀释液,加压冲洗3~4次,仍然无效的,进行常规泪道探通术操作。1.3治疗标准无流泪、无分泌物、泪道冲洗畅通,反之则无效,结果168例,230眼,治愈166例,228眼,其中按摩治疗49例,冲洗86眼,探通31眼。。。

RESULTS: Rapidly progressive crystalline lens opacification occurred in 9 eyes within 4 to 15 weeks after diagnosis of Acanthamoeba keratitis.

结果:在诊断为棘阿米巴角膜炎后,9只眼在4-15周内迅速发生了晶状体的混浊。3只眼与炎性并发症相关,包括前巩膜炎(2只眼)和虹膜睫状体炎(1只眼)。

The clinical pictures and fluorescein angiograms are presented. The pathogenesis of fundus change in sympathetic ophthalmia is discussed.

本报告揭示交感性眼炎引起视力减退的直接原因在於渗出性视网膜剥离,在发病的各个时期中显现不同的多样化之眼底变化,早期正确诊断和适切的治疗可以避免严重的合并症而保存相当良好的视力。

Results The incidence of sympathetic ophthalmia was high in youth.The perforating injury was the most common exciting factor(88.00%) More wounds were at corneal limbus(59.32%). The latent period in 2 - 8 weeks was more common(47.89%).

结果 交感性眼炎多发生于青壮年,致伤原因多为眼球穿孔伤,占88 0 0 %;受伤部位为角膜缘者最多,占 5 9 3 2 %;潜伏期 9天~ 3 6年,以 2~ 8周者最多,占 47 89%;年龄越小发生后段改变的可能性越高,潜伏期在 8周~ 1年的病例越趋向于发生后段改变。

Aim To compare the effects of different nutritious eyedrops on corneal healing in electric ophthalmitis.

目的 比较不同的眼用营养剂对电光性眼炎患者角膜上皮愈合时间、痛觉和泪膜稳定性的影响。

Objective To study preliminarily the clinical significance of the endogenous pathogenies and prevention,cure and avoidance of recrudesce of uveitis with Blood Rheology.

对血液流变学在眼葡萄膜炎的内源性病因以及预防、治疗和防止复发等方面的临床意义作初步的探讨。

METHODS:The neonatus with obstruction of lacrimal passage and dacryocystisis were given homologous treatment such as extrusion,massage and rinsing lacrimal passage weekly.114 cases(169 eyes) with severe infection and mass purulent secretion underwent bacteria cultivation and selectivity medication combined with rinsing and probing after antimicrobial susceptibility test.

对单纯泪道阻塞及泪囊炎的新生儿采用相应的泪道挤压、按摩及生理盐水每周冲洗泪道。对严重感染冲洗伴有大量脓性分泌物的新生儿做细菌培养加药敏试验后选择用药合并冲洗、探通等方法治疗114例169眼。

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