眼炎

Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome

目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析，并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography，FFA)、吲哚青绿血管造影(indocyanine green angiography，ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例，73.5%)，双眼同时患病118例(80.8%)；后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%)；前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例，98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%)；后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障；毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现；炎症活动期FFA典型表现为斑驳状高荧光，ICGA发现脉络膜血管扩张、通透性增高等改变；VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎，随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。

RESULTS: Rapidly progressive crystalline lens opacification occurred in 9 eyes within 4 to 15 weeks after diagnosis of Acanthamoeba keratitis. Three were associated with inflammatory complications, including anterior scleritis (2 eyes) and iridocyclitis (1 eye).

结果：在诊断为棘阿米巴角膜炎后，9只眼在4-15周内迅速发生了晶状体的混浊。3只眼与炎性并发症相关，包括前巩膜炎（2只眼）和虹膜睫状体炎（1只眼）。

2 Treatment method is less than a month treat a little patient to use method of massage drop medicine first, treat 1~2 week, 2~3min is massaged before daily drop medicine, be more than the little patient of a month, if drop medicine treats 1~2 week to did not see,improve to still have apparently weep the person that reach secretion, applied medicaments pressurization rinses lachrymal path, use pinhead of vein of skin of tube head of nylon of self-restrained and different type to grind blunt, make rinse a needle continuously, groovy operation, after syringe needle inserts lachrymal canaliculus, nylon the canal is secured with adhesive plaster at the head, undertake rinsing, 1 / D, with oxygen fluorine to lotion Sha Xing adds loose diluent of rice of ground a place of strategic importance, pressurization rinses 3~4 second, invalid still, undertake probing of groovy tear path is operated.

我科自2000年1月至2006年12月，共治疗新生儿泪囊炎178例、230眼，疗效满足，报告分析如下。1资料和方法1.1一般资料新生儿泪囊炎患儿168例、230眼，男102例，女66例，年龄：2d~3个月，均为本院眼科门诊确诊的新生儿泪囊炎患儿。1.2治疗方法小于1个月的首次就治患儿采用按摩滴药法，治疗1~2周，每日滴药前按摩2~3min，大于1个月的患儿，如滴药治疗1~2周未见明显好转仍有流泪及分泌物者，应用药物加压冲洗泪道，采用自制不同型号尼龙管头皮静脉针头磨钝，制成直的冲洗针，常规操作，针头插入泪小管后，将尼龙管用胶布固定于头部，进行冲洗，1次/d，冲洗液用氧氟沙星加地塞米松稀释液，加压冲洗3~4次，仍然无效的，进行常规泪道探通术操作。1.3治疗标准无流泪、无分泌物、泪道冲洗畅通，反之则无效，结果168例，230眼，治愈166例，228眼，其中按摩治疗49例，冲洗86眼，探通31眼。。。

RESULTS: Rapidly progressive crystalline lens opacification occurred in 9 eyes within 4 to 15 weeks after diagnosis of Acanthamoeba keratitis.

结果：在诊断为棘阿米巴角膜炎后，9只眼在4-15周内迅速发生了晶状体的混浊。3只眼与炎性并发症相关，包括前巩膜炎（2只眼）和虹膜睫状体炎（1只眼）。

One of the most common eye complications in IBD is uveitis, defined as painful inflammation of the uvea—the middle layer of the eye wall.

IBD中最常见的眼部并发症之一是眼色素层炎/葡萄膜炎，它是眼色素层/葡萄膜——眼壁中层——的疼痛的炎症。

TNF and IL-2 in the aqueous humor of this animal model increase, use T cell surfuce differential antigen immunohistochemical methed to check the pathological uvea tissues, many positive cells can be found, indicates the pathological changes of uvea tissues are caused by immuno-hyperactivity.

BSA诱导的兔实验性葡萄膜炎，眼部症状和全身表现类似于脏腑热毒炽盛型葡萄膜炎，选用消炎Ⅰ号方治疗后眼部炎症积分值降低，表明消炎Ⅰ号方有减轻葡萄膜炎炎症的作用。

Too few proteins lead to night blindness, perifollicular hyperkeratosis, xerophthalmia, keratomolacia, increased morbidity and mortality in young children.

维生素不足可导致夜盲、毛囊周角化过度、异物笥眼炎、儿童发病率我死亡率增高等。

According to patients' condition,a great deal of antibiotic and adrenocortical had been given.

对20例外伤性内眼炎患者全身和局部大剂量应用抗生素、激素。

Objective:To explore the efficacy of subconjunctival injection of antibiotic and adrenocortical in treating traumatic endophthalmitis.

张宁目的：探讨球注抗生素、激素治疗外伤性内眼炎的疗效。

Repeated corneal perforation occurred in nine eyes, with primary diseases of herpes simplex keratitis (HSK; four eyes), Mooren ulcer, necrotizing keratitis and scleratitis, bacterial keratitis, and alkali burn. Corneal grafts perforated in 31 eyes, resulting from recurrent HSK, implant autoproteolysis, bacterial infections, recurrent Mooren ulcer, immunologic rejection, trauma, and fungal recurrence.

本研究中有9只眼发生了反复的角膜穿孔，其原发疾病分别为单疱病毒性角膜炎（HSK，4只眼），蚕食性角膜溃疡（2只眼），坏死性角巩膜炎（1只眼），细菌性角膜炎（1只眼）和碱烧伤（1只眼）。31只眼发生了角膜植片穿孔，分别由单疱病毒性角膜炎复发（8只眼），角膜植片自溶（7只眼），细菌感染（6只眼），蚕食性角膜溃疡复发（4只眼），免疫排斥反应（3只眼），外伤（2只眼）和真菌复发（1只眼）引起。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。