相比

Results Punctiform erosion, hemorrhage were observed by nake eyes in each groups. Epithelium cellular necrosis, defluxion, neutrophil being dominant in propria lamina and intact glandular were observed with microscopy. The erosion became severe with the successive stimulate of ethanol. There is no difference between distillate spirit and sodium chloride rats in Guth in 7th day, but Guth in distillate spirit rats was higher than that in sodium chloride rats in 30th day. PGE2, TGF-α contents in gastric mucosa of treated group increased significangly compared with control group. PGE2 showed no difference between each group in 7th and 30th day; TGF-α in gastric mucosa of distillate spirit and sodium chloride rats decreased after 1 month.

结果 茅台组、乙醇组、生理盐水组胃黏膜均肉眼可见程度不同的点状糜烂、出血；光镜下黏膜部分上皮坏死脱落，固有层以中性粒细胞为主炎性细胞浸润，腺体结构基本完整，病变随时间延长有所加重，Guth积分1周茅台组与生理盐水组差异无统计学意义，1月两者相比差异有统计学意义；茅台组、乙醇组胃黏膜组织内PGE2水平与生理盐水组相比明显增高，同时TGF-α表达增强；但PGE2水平各组间1周与1月相比差异无统计学意义；TGF-α表达强度在茅台组、生理盐水组1月后逐渐降低，差异有统计学意义。

Results The GRK5 protein level in Parkinson's disease α-synuclein transgenic mice was increased to different degrees compared with that in non-transgenic littermate control mice, and the protein and mRNA expressions of GRK5 in 9-month old A53T mutant mice were higher than those in NLC mice, but there were no significant changes in the 3 month and 6 month old A53T mutant mice.

结果 各组帕金森病α-synuclein转基因小鼠与阴性对照小鼠相比，GRK5蛋白表达水平均有不同程度的增加，并且随着转入的h-α-syn蛋白表达水平的高低而有所变化。3月龄和6月龄帕金森病转基因模型小鼠与同月龄阴性对照组小鼠相比，GRK5的mRNA和蛋白水平没有变化；而9月龄帕金森病转基因模型小鼠与同月龄阴性对照组小鼠相比，GRK5的mRNA和蛋白水平都有所增加。

The changes of nutrition in milk treated with different technologies are also determined. Results showed that, 1 higher pressure, longer holding time and more alternative times favour a larger destruction of microorganisms; 2 the combined effect of hurdle technology and pressure on the destruction of microorganisms in fresh raw milk is more effective than only using pressure treatment, among which the effect of ε-polylysine on inactivation of microorganism in fresh raw milk is more effective than that of Nisin with the same concentration of 100mg/L; 3 the whole proteins in milk treated by the different types of sterilization have been detected by SDS-PAGE electrophoresis, and comparing with the whole proteins' electrophoretogram of fresh raw milk, we found that the first spectrum band near the negative pole was disappeared and the colours of the second spectrum band was tint in UHT, pasteurism and 500MPa treated milks, which was suggested that some proteins' subunits were dissociated, but the 400MPa treated milk showed the similar eletrophoretogram with the fresh raw milk; 4 the loss of threonine, VA and VC in high pressure treated milk was more less than those in pasteurism treated milk, in particular threonine and VA were almost retained, and the contents of VB1 and VB2 in the former are also more than that in the latter; 5 high pressure treated milk had longer shelf life than pasteurism treated milk, extending the sale semidiameter of milk.

压力越高，保压时间越长，交变次数越多，杀菌效果越好；2）采用栅栏技术对牛乳中的微生物具有更有效的杀菌作用，其中相同浓度的（终浓度100mg/L）ε-聚赖氨酸较Nisin具有更强的杀菌效果；3）利用SDS-PAGE电泳研究了不同杀菌方式对牛乳总蛋白的影响，发现经UHT、巴氏和500MPa交变处理的牛乳与生鲜牛乳相比其总蛋白电泳图谱靠近负极方向第一条谱带消失，第二条谱带颜色变浅，由此推测经上述处理后牛乳中有一些蛋白质的亚基发生了解离，而经400MPa交变处理的牛乳与生鲜牛乳的总蛋白电泳图谱相似；4）超高压牛乳营养成分与生鲜牛乳相比，苏氨酸、VA、VC在超高压处理中受到的破坏明显比巴氏杀菌小得多，特别是苏氨酸和VA几乎完全被保留下来，而VC含量也要比巴氏奶高出25%以上，对于VB1、VB2，检测数据也表明，超高压灭菌对其破坏要比巴氏灭菌小，其含量分别比巴氏杀菌牛乳高出9.5%和2.6%；5）与巴氏杀菌乳相比，超高压杀菌有助于延长牛乳的保质期，扩大牛乳的销售半径。

The results of immuhistochemistry show: compared with normal retina, more 3-NT-positive cells and iNOS-positive cells appear in inner nucleus layer of diabetic retina; less eNOS-positive cells appear in inner nucleus layer and vascular endoderm of diabetic retina; less nNOS -positive cells appear in inner nucleus layer of diabetic retina; more ET-positive cells, ETRA- positive cells, ETRB- positive cells appear in inner nucleus layer of diabetic retina; moreα- synuclein- positive cells appear in ocular cone and rod layer of diabetic retina. Conclusions 1. RFDD-PCR is an efficient technique for research diseases genomics as a mass screening to complete gene expression with the identifying of candidate gene related to disease.

免疫组织化学结果显示：13-NT和NOS：与正常视网膜相比，8周糖尿病大鼠视网膜中，INL的3-NT和iNOS免疫阳性细胞明显增多，INL和血管内皮层的eNOS阳性细胞明显减少，INL的nNOS阳性细胞也明显减少；2ET及ETR：与正常视网膜相比，8周糖尿病大鼠视网膜中，ET、ETRA、ETRB免疫阳性细胞明显增多，增多的阳性细胞主要集中于INL，而在血管内皮层增多不明显；3α-synuclein：与正常视网膜相比，8周糖尿病大鼠视网膜中，α-synuclein免疫阳性细胞明显增多，增多的阳性细胞主要集中于视网膜视锥视杆层。

To compare the temperature diversity by collecting and analysing these infrared thermogram data. Results: While the operator just put their hands to the back of the quizzee for 3 minutes, the temperature of Xinshu and Dazhu rised and then descent gradually; But the temperature rised all the same about another 3 minutes while the operater using the vibrating manipulation; The temperature of Laogong and Zhongchong rised gradually, especially in 120 seconds and 90 seconds after using the vibrating manipulation.

结果：三组操作者在空置后3min，心俞穴和大杼穴处温度均出现变化，且与操作前温度有显著差别(P.05)；在空置3min后，被操作者的心俞处以及大杼处的温度呈自然下降趋势；而在行掌振法时，被操作者心俞处以及大杼处的温度变化，不仅发生在3min后，而且可延续到振法停止后的1min到3min内，与操作前温度相比，有显著差别(P.05)；在空振中，高年资医师的劳宫处和中冲处温度呈现逐渐上升趋势，在振法进行到90s时，中冲处温度出现显著变化，与开始温度相比，有显著差别(P.05)，而劳宫处的温度则是在120s时，出现显著变化，与开始温度相比，有显著差别(P.05)。

Objective To examine the value of Edaravone in the treatment of vascular dementia through ethologic and pathologic changes induced by chronic cerebral ischemiaMethods Wistar rats were randomly divided into sham operated group,model group,edaravone group and duxil groupThe chronic cerebral hypoperfusion models were made by permanent bilateral occlusion of both common carotid arteriesThe memory ability and ultramicrostructure of brain tissue were observedResults The escape latencies in model group were more significantly prolonged than that in the other groups (P＜005)But there was no significant difference between edaravone and duxil groupAnd pathologic changes observed by electron microscope in nerve cell of edaravone group and duxil group and model group were fairly light than that in sham operated groupEdaravone group had increased mitochondrium and frontal membranous synaptic vesicle and more productive metabolic activityConclusions Edaravone can lessen injures of hippocampal neurons loss to improve the spatial learning and memory abilitiesAnd it is proved further that edaravone can treat VD

目的 观察依达拉奉对慢性缺血致血管性痴呆大鼠行为学及形态学的影响，探讨依达拉奉在治疗VD中的应用价值。方法实验分假手术组、模型组及都可喜对照组及依达拉奉治疗组，应用双侧颈总动脉结扎方法制备慢性脑缺血大鼠痴呆模型，观察各组大鼠的记忆功能及脑组织超微结构改变。结果缺血组水迷宫表现同对照组、都可喜组及依达拉奉组相比有显著差异(P＜005)，依达拉奉组与都可喜组相比未见显著差异。同时电镜观察结果也发现依达拉奉组及都可喜组与模型组及假手术组相比神经细胞病理改变较轻，且依达拉奉组线粒体及前膜突触小泡增多，代谢活动较都可喜组旺盛。结论依达拉奉可能通过减轻海马神经元的损伤来改善慢性脑缺血大鼠空间学习记忆障碍，证明依达拉奉对慢性缺血致VD大鼠具有治疗作用。

The lumbar were cut and stined with Masson Golder Trichrome for bone histomorphomemetric analysis. Result: The QiangGuYin group ovariectomized rats' in 1.5m, 4.5m, 6m, Tb. Th compared with Fosamax group with statistical significance; in 4. 5m, 6m, compared with control group in Tb. sp with statistical significance.

结果：强骨饮组1.5月、4.5月、6月骨小梁厚度与福善美组数据相比具有统计学意义，4.5月，6月骨小梁间距与福善美组相比具有统计学意义，强骨饮组和福善美组数据与空白组相比骨体积分数、骨小梁厚度、骨小梁间距都具有统计学意义。

RESULTS: The results showed that the water extract of phellodendron and one of its main components increased the cell membrane fluidity in the inactive state, but the other two components, berberine and jatrorrhizine, decreased the cell membrane fluidity.

结果：在无ConA刺激时，黄柏的水提物可提高小鼠脾细胞膜的流动性，6.25%的浓度与对照组相比有极显著性差异；小檗碱与药根碱可降低脾细胞膜的流动性，与对照组相比均有显著性差异；巴马汀可提高脾细胞膜的流动性，与对照组相比有极显著性差异。

RESULTS: The results showed that the water extract of phellodendron and one of itsmain components increased the cell membrane fluidity in the inactive state, but the other two components, berberineand jatrorrhizine, decreased the cell membrane fluidity.

结果：在无ConA刺激时，黄柏的水提物可提高小鼠脾细胞膜的流动性，6.25％的浓度与对照组相比有极显著性差异；小檗碱与药根碱可降低脾细胞膜的流动性，与对照组相比均有显著性差异；巴马汀可提高脾细胞膜的流动性，与对照组相比有极显著性差异。

The expression changes of relating-apoptosis gene proteins (bcl-2, bax) were detected by immunohistochemistry before and after treating with the Agaricus Blazei Murill extract to explore the possible mechanisms of inducing apoptosis for MGC-803 cells in vitro. Results: The Agaricus Blazei Murill extract significantly inhibited the proliferation of gastric cancer cells in vitro and the inhibitive effects were depended on the medicine concentration and treating times. After treating 24 hours on the gastric cancer cells with the morphologic changes of apoptosis with chromatin margination, karyopyknosis, karyorrhexis were found by the light.

结果：(1)通过细胞培养和MTT法，表明长白山姬松茸在体外对MGC-803细胞株有明显的抑制作用，加药组与对照组相比其生长抑制率有显著性差异(P＜0.01)，而且这种抑制作用呈现浓度和时间的依赖性；(2)通过集落形成率的测定结果表明，加药组与对照组相比其集落形成率和集落形成抑制率有明显差异(P＜0.01)，说明长白山姬松茸对MGC-803胃癌细胞株有明显抗增殖作用；(3)光镜观察结果表明，加药组可见细胞脱水浓缩伊红染色增强，胞体缩小，内含高度浓缩的胞核呈深蓝色等典型细胞凋亡形态；经AO／EB荧光染色观察结果表明，当终浓度为1.0mg／ml的姬松茸提取物作用于MGC-803胃癌细胞24h后，其凋亡率和破膜率与自然凋亡率与破膜率相比，均有显著性差异，其凋亡率86.3％(P＜0.001)，破膜率为41.6％(P＜0.01)，说明姬松茸确实有诱导MGC-803胃癌细胞凋亡的作用，同时也有细胞毒作用，但以诱导细胞凋亡为主；(4)免疫组化结果表明，用药前后凋亡相关基因的BCl-2、Bax蛋白均有显著性的改变(P＜0.001)。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。