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相思子毒素

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This literature on abrin has been reviewed with respect to:the abrin structural characteristics, action mechanism of causing poison of abrin, application prospect in clinical of abrin.

本文综述了有关相思子毒素的分子结构特点,毒性机制和在临床中的应用前景。

Abrin;structural characteristics;immunotoxin;clinical application

相思子毒素;结构特点;免疫毒素;临床应用

Abrin is one of the potent toxins isolated from the beans of plant abrus precatorius.the toxic protein consists of two disulfide-bonded subunits,the a and b chains.the b chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis.after entering the cells,the a chain catalytically inactivates 60s ribosomal subunits by removing adenine position 4324 of 28s r–rna,and thereby inhibits protein biosynthesis.

相思子毒素是从豆科植物(abrus precatorius l。)种子中分离的一种细胞毒性蛋白。它由a,b两条链组成,由一个二硫键相联,b链具有半乳糖凝集活性,可与细胞膜上受体结合,帮助a链进入细胞内,a链进入细胞催化失活60s核糖体亚基,从而使细胞蛋白合成被抑制。

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Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势,并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。

This dramatic range, steeper than the Himalayas, is the upturned rim of the eastern edge of Tibet, a plateau that has risen to 5 km in response to the slow but un stoppable collision of India with Asia that began about 55 million years ago and which continues unabated today.

这一引人注目的地域范围,比喜马拉雅山更加陡峭,是处于西藏东部边缘的朝上翻的边框地带。响应启始于约5500万年前的、缓慢的但却不可阻挡的印度与亚洲地壳板块碰撞,高原已上升至五千米,这种碰撞持续至今,毫无衰退。