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The mouse embryonic stem cells cDNA library was screened by yeast two-hybrid assay,some candidate molecules were get,including DDX39 DEAD (Asp-Glu-Ala-Asp box polypeptide 39, BAT1A(HLA-B-associated transcript 1A), NAC1 ( nucleus accumbens-1 ), BicD2 (bicaudal D homolog 2)、MLL3 (myeloid/lymphoid or mixed-lineage leukemia 3). NAC1 and MLL3 were associated with regulation of gene transcription. DDX39 andBAT1A were associated with pre-mRNA processing and mRNA export from nucleus to cytoplasm. BicD2 was associated with the regulation of Golgi body.

通过利用酵母双杂交方法,以小鼠全长Plk1作为诱饵蛋白筛选小鼠胚胎干细胞cDNA文库中与其相互作用的蛋白,获得了DDX39DEAD(Asp-Glu-Ala-Aspbox polypeptide 39、BAT1A(HLA-B-associated transcript 1A)、NAC1(nucleus accumbens-1)、BicD2(bicaudal D homolog 2)、MLL3(myeloid/lymphoid or mixed-lineage leukemia 3)等几个候选蛋白,其中NAC1、MLL3与基因的转录调控有关,DDX39、BAT1A与mRNA前体的剪切、加工及mRNA从细胞核转运到细胞质紧密相关,而BicD2与高尔基体的调控紧密相关,提示我们Plk1与基因转录、mRNA前体的剪切、加工、mRNA的运输及胞质分裂中高尔基体的调控有关。

Through image digitalization and digital image frame analysis, the dynamic change of arc state and droplet motion before and after its detachment from wire tip can be quantitively described. The kinematical and kinetical parameters of droplet motion can be solved. The development of the system provides a new way for the study of metal transfer mechanisms and the interaction between droplet transfer and weld pool.

该系统通过对高速摄影图象的数字化处理及时间图象序列分析,可以对熔滴过渡过程中电弧变化的动态过程及熔滴脱落前后的运动过程进行定量分析,并可提取出熔滴运动的各种运动学和动力学参数,为进一步的熔滴过渡机理及熔滴与熔池相互作用的研究提供了新的研究手段。

This paper describes the distribution of potentials and current densities and the chemical changes in the presence of cathodic protection,the mechanism of cathodic protection against crevice corrosion,the mechanism of microbiologically influenced corrosion of pipeline steel beneath disbonded coatings.

综述了在有阴极保护的条件时剥离涂层下缝隙内电位电流的分布和化学环境的变化、阴极保护防止缝隙腐蚀的机理、微生物腐蚀的机理以及前人提出的关于剥离涂层下微生物腐蚀与阴极保护相互作用的规律,并展望了对于解决剥离涂层下微生物腐蚀难题需进一步的实验研究

On the basis of an integrated analysis of the geochemical features of these volcanic rock associations,this paper concludes that thebasalts originated mainly from interaction between mantle-derived magma and low-crustal materials, and rhyolitic volcanic rocks resulted from thermal and chemical interaction between basaltic magma and the upper part of crustal materials.Basalts and rhyolites in different cycles have different source regions,and they are products of multiperiodic pulsive layer partial melting.

根据对火山岩地球化学特征的综合分析表明,玄武岩主要为幔源岩浆与下部地壳岩石相互作用的产物,而流纹岩则为玄武岩浆与上部地壳物质进行热及成分交换的结果,不同旋回的玄武岩和流纹岩有不同的源区,为多次脉动分层部分熔融的产物。

Ordosica biomass and density was dependant on that of soil moisture, and in particular, there existed a significant positive correlation between the biomass and the moisture, indicating that on semifixed dune, soil moisture played a decisive role in the spatial heterogeneity of plant population.

由于沙丘地形对降水量的再分配在土壤湿度分布中的作用,土壤湿度和油蒿种群空间异质性相互作用的结果为地形的缀块性→土壤湿度分布的缀块性→油蒿种群分布的缀块性→油蒿生物量和密度的缀块性。

We proposed that π-interrupted spiro framework is an effective tool to tune the intermolecular interaction of chromophore moieties, which has been confirmed by single crystal X-ray diffraction analyses.

另外,我们设想螺桥是调制光电功能基团超分子作用的有效工具,设计了一个含螺桥的氧化噻吩寡聚物,这是一个有效的讨论螺桥是如何通过自身的参与来有效地调制光电功能基团的相互作用的模型。

Based on the p rinci ple of system, a basin,taking water as a intermediary,is regarded as a open and complicated system through the interacti on between mankind and nature, and a su stainable development model of the basin system proposed.

从系统的观点出发,把流域看成为一个以水为媒体,人与自然相互作用的开放的复杂巨系统,提出了一种流域系统可持续发展的模式,分析和研究了流域系统的运行机制及测度指标体系,进而提出一种层次分析方法和神经网络方法相结合的综合测度方法。

The tanglesome problem,which includes the coupling of detonation of highexplosives,propagation of blast wave and interaction of explosion wave and shellstructures,is resolved by a staged calculation procedure.A numerical simulation tothe elasto-plastic structural response of the double-walled explosion containmentvessels closed with flat head,which has not been reported by other literatures before,was performed.The simulated results are in good agreement with that of theexperiment.The characteristics of the dynamic response of the vessels weresummarized.Some noticeable new phenomena were pointed out.

在数值分析方面,本文对一个包含有装药爆炸、爆炸波传播、爆炸冲击波与结构相互作用的复杂耦合问题,提出了分段解耦的计算方法,并首次完成了带平板封头的双层圆柱形爆炸容器弹塑性结构响应的数值模拟,得出了与实验基本一致的结果,总结了圆柱形爆炸容器弹塑性结构响应的基本特点,并发现了一些值得注意的新现象和新问题。

The structure models of zirconium sulfate tetrahydrate and silica have been built. The binding morphology, charge distribution and energy change were also studied. It is deduced that the strong interactions between the active composition and support through hydrogen binding and dehydrate mode promise that zirconium sulfate tetrahydrate can disperse uniformly on the surface of support.

在对硅胶表面结构单元和四水硫酸锆单体空间模型结构参数进行优化的基础上,依据四水硫酸锆与硅胶载体表面的成键状态、电荷布居及能量变化,从理论上分析了四水硫酸锆与载体表面之间静电和脱水的相互作用的合理模型及硅胶负载型硫酸锆的结构稳定性,阐明了硫酸锆在载体表面的分散趋向于单分散的特征。

The linear relationship between boiling temperature and salt concentration was verified by the experimental results and thermodynamical theory.

实验结果和热力学基本原理确证了体系的沸点与加入盐浓度间的线性关系,计算了各双液组成下体系的盐效应常数,分析了实验中产生&异常&现象的原因,探讨了溶液内部粒子相互作用的规律,通过用相律、盐效应理论、静电理论、溶剂化理论的解释,得到了一些具有理论价值的结论。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。