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直肠给药

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To the descending colon and rectum , because of the pH increased the activity of proteolytic enzymes increased, so it is generally believed that the ascending colon where is the best delivery site for protein peptide drugs.

至降结肠及直肠等处,由于 pH 值升高,蛋白水解酶的活性明显增强,故一般认为升结肠处为蛋白多肽类药物的最佳给药部位。

Results : The effective and excellent rates of the rectally administered group were 94.9% and 82.1% respectively.

结果:MST直肠给药有效率和显著有效率分别为94 。9%和82.1%。

MST was given orally for the first 5 days and then rectally for the next 5 days.

39例伴有中、重度癌性疼痛的患者先口服MST5天,后改为MST直肠给药连用5天。

Objective To evaluate the analgesic effect of treating cancer pain by MS-contin administered rectally.

目的 观察美施康定直肠给药治疗癌症疼痛的止痛效果。

In a double-blind, placebo-controlled design we randomized 120 children, aged 1-9 yr, undergoing orthopedic or soft tissue surgery, into 3 groups to receive either acetaminophen 60 mg/kg rectally and 40 mg/kg orally, ketoprofen 2 mg/kg IV twice, or the combination of the active drugs.

在这项双盲、安慰剂对照试验中,我们随机抽取了120个一至九岁的行软组织或畸形矫正手术儿童,将他们分成三组,一组为经直肠给扑热息痛60 mg/kg 或口服给药40 mg/kg ,一组为静脉给优布芬2 mg/kg,另一组为联合给药。

It is a safe and effective agent; has a rapid onset and short duration of action; and is easily administered orally, intravenously, rectally, or intramuscularly.

它安全有效,半衰期短易于代谢,口服、静注、经直肠给药或肌注都很方便。

The key point is it acts directly on the rectum with no side effects.

关键的是,它是经直肠给药,没有任何副作用。

The method of proctoclysis of Chinese traditional medicine is a new treatment way of combining clusis and TCM catharsis, by this means, Chinese traditional medicine can be absorbed promptly through rectal mucous membrane and entrance Greater circulation to treating total body or local disease. It has many advantages on treatment for diseases, such as convenient use, spreading easily, becoming effective rapidly and reliable effect, no bad response and ill effect, and so on.

中药直肠滴注法是中医学的&导法&与现代医学的灌肠法相结合而产生的一种新的给药方法,药物可通过直肠粘膜迅速吸收,进入大循环,发挥药效以治疗全身或局部疾病,具有方法简便、易于推广、应用范围广、见效快、疗效可靠、无明显不良反应和毒副作用等优点,该法用于脑出血急性期昏迷患者的抢救取得了好的疗效。

The purpose of the research is to exploring the mechanism of proctoclysis of Tongfuxingshen liquid treating unconscious patients with cerebral hemorrhage and encephaledema, cerebral vessels permeability and expression of HSP70, HO-1mRNA after cerebral hemorrhage in rats by TCM theory and clinical, experiment. Providing the theoretic and clinical, experimental evidence for it, and exploring the new administration ways to treating acute intracerebral hemorrhage.

本文试图从理论、临床和实验研究探讨导师经验方——通腑醒神胶囊直肠滴注治疗出血中风的机理,通过观察对脑出血神昏病人意识状态及对脑出血大鼠脑水肿及脑血管通透性、脑组织HO-1mRNA和HSP70表达的影响,探讨通腑醒神液直肠滴注治疗出血中风的作用机制,为通腑醒神液直肠滴注治疗脑出血提供理论、临床及实验依据,探索抢救脑出血急性期昏迷患者新的给药途径。

Objective To explore the clinical value of rectal administration of clonazepam solution for seizure control in children.

安定溶液直肠给药能及时控制惊厥发作,这对静脉穿刺困难或医院外惊厥发作的现场急救有重要价值。

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